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Items: 1 to 20 of 92

1.

COX-2 from the injury milieu is critical for the initiation of periosteal progenitor cell mediated bone healing.

Xie C, Ming X, Wang Q, Schwarz EM, Guldberg RE, O'Keefe RJ, Zhang X.

Bone. 2008 Dec;43(6):1075-83. doi: 10.1016/j.bone.2008.08.109. Epub 2008 Aug 16.

2.

Periosteal progenitor cell fate in segmental cortical bone graft transplantations: implications for functional tissue engineering.

Zhang X, Xie C, Lin AS, Ito H, Awad H, Lieberman JR, Rubery PT, Schwarz EM, O'Keefe RJ, Guldberg RE.

J Bone Miner Res. 2005 Dec;20(12):2124-37. Epub 2005 Aug 8.

3.

Periosteal BMP2 activity drives bone graft healing.

Chappuis V, Gamer L, Cox K, Lowery JW, Bosshardt DD, Rosen V.

Bone. 2012 Oct;51(4):800-9. doi: 10.1016/j.bone.2012.07.017. Epub 2012 Jul 28.

PMID:
22846673
4.

Osteopenia and impaired fracture healing in aged EP4 receptor knockout mice.

Li M, Healy DR, Li Y, Simmons HA, Crawford DT, Ke HZ, Pan LC, Brown TA, Thompson DD.

Bone. 2005 Jul;37(1):46-54.

PMID:
15869929
5.

Expression of endogenous BMP-2 in periosteal progenitor cells is essential for bone healing.

Wang Q, Huang C, Xue M, Zhang X.

Bone. 2011 Mar 1;48(3):524-32. doi: 10.1016/j.bone.2010.10.178. Epub 2010 Nov 5.

6.

COX-2 is necessary for venous ligation-mediated bone adaptation in mice.

Stevens HY, Meays DR, Yeh J, Bjursten LM, Frangos JA.

Bone. 2006 Jan;38(1):93-104. Epub 2005 Aug 24.

PMID:
16122997
7.

Osteoblast-Specific Loss of IGF1R Signaling Results in Impaired Endochondral Bone Formation During Fracture Healing.

Wang T, Wang Y, Menendez A, Fong C, Babey M, Tahimic CG, Cheng Z, Li A, Chang W, Bikle DD.

J Bone Miner Res. 2015 Sep;30(9):1572-84. doi: 10.1002/jbmr.2510.

8.

Biglycan modulates angiogenesis and bone formation during fracture healing.

Berendsen AD, Pinnow EL, Maeda A, Brown AC, McCartney-Francis N, Kram V, Owens RT, Robey PG, Holmbeck K, de Castro LF, Kilts TM, Young MF.

Matrix Biol. 2014 Apr;35:223-31. doi: 10.1016/j.matbio.2013.12.004. Epub 2013 Dec 25.

9.

Structural bone allograft combined with genetically engineered mesenchymal stem cells as a novel platform for bone tissue engineering.

Xie C, Reynolds D, Awad H, Rubery PT, Pelled G, Gazit D, Guldberg RE, Schwarz EM, O'Keefe RJ, Zhang X.

Tissue Eng. 2007 Mar;13(3):435-45.

PMID:
17518596
10.

A novel murine segmental femoral graft model.

Tiyapatanaputi P, Rubery PT, Carmouche J, Schwarz EM, O'keefe RJ, Zhang X.

J Orthop Res. 2004 Nov;22(6):1254-60.

11.

Thrombospondin-2 influences the proportion of cartilage and bone during fracture healing.

Taylor DK, Meganck JA, Terkhorn S, Rajani R, Naik A, O'Keefe RJ, Goldstein SA, Hankenson KD.

J Bone Miner Res. 2009 Jun;24(6):1043-54. doi: 10.1359/jbmr.090101.

12.

Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4.

Xie C, Liang B, Xue M, Lin AS, Loiselle A, Schwarz EM, Guldberg RE, O'Keefe RJ, Zhang X.

Am J Pathol. 2009 Aug;175(2):772-85. doi: 10.2353/ajpath.2009.081099. Epub 2009 Jul 23.

13.

Reduced COX-2 expression in aged mice is associated with impaired fracture healing.

Naik AA, Xie C, Zuscik MJ, Kingsley P, Schwarz EM, Awad H, Guldberg R, Drissi H, Puzas JE, Boyce B, Zhang X, O'Keefe RJ.

J Bone Miner Res. 2009 Feb;24(2):251-64. doi: 10.1359/jbmr.081002.

14.

Activation of the Hh pathway in periosteum-derived mesenchymal stem cells induces bone formation in vivo: implication for postnatal bone repair.

Wang Q, Huang C, Zeng F, Xue M, Zhang X.

Am J Pathol. 2010 Dec;177(6):3100-11. doi: 10.2353/ajpath.2010.100060. Epub 2010 Oct 22.

15.

Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice.

Sheng MH, Zhou XD, Bonewald LF, Baylink DJ, Lau KH.

Bone. 2013 Jan;52(1):133-44. doi: 10.1016/j.bone.2012.09.027. Epub 2012 Sep 29.

PMID:
23032105
16.

Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair.

Zhang X, Schwarz EM, Young DA, Puzas JE, Rosier RN, O'Keefe RJ.

J Clin Invest. 2002 Jun;109(11):1405-15. Erratum in: J Clin Invest 2002 Oct;110(8):1211.

17.

MCP/CCR2 signaling is essential for recruitment of mesenchymal progenitor cells during the early phase of fracture healing.

Ishikawa M, Ito H, Kitaori T, Murata K, Shibuya H, Furu M, Yoshitomi H, Fujii T, Yamamoto K, Matsuda S.

PLoS One. 2014 Aug 18;9(8):e104954. doi: 10.1371/journal.pone.0104954. eCollection 2014.

18.

The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice.

Long T, Zhu Z, Awad HA, Schwarz EM, Hilton MJ, Dong Y.

Biomaterials. 2014 Mar;35(9):2752-9. doi: 10.1016/j.biomaterials.2013.12.039. Epub 2014 Jan 3.

19.

The spatiotemporal role of COX-2 in osteogenic and chondrogenic differentiation of periosteum-derived mesenchymal progenitors in fracture repair.

Huang C, Xue M, Chen H, Jiao J, Herschman HR, O'Keefe RJ, Zhang X.

PLoS One. 2014 Jul 2;9(7):e100079. doi: 10.1371/journal.pone.0100079. eCollection 2014.

20.

Role of donor and host cells in muscle-derived stem cell-mediated bone repair: differentiation vs. paracrine effects.

Gao X, Usas A, Proto JD, Lu A, Cummins JH, Proctor A, Chen CW, Huard J.

FASEB J. 2014 Aug;28(8):3792-809. doi: 10.1096/fj.13-247965. Epub 2014 May 19.

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