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Items: 1 to 20 of 89


A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors.

Antoku S, Saksela K, Rivera GM, Mayer BJ.

J Cell Sci. 2008 Sep 15;121(Pt 18):3071-82. doi: 10.1242/jcs.031575.


Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals.

Antoku S, Mayer BJ.

J Cell Sci. 2009 Nov 15;122(Pt 22):4228-38. doi: 10.1242/jcs.054627. Epub 2009 Oct 27.


c-Abl phosphorylates Dok1 to promote filopodia during cell spreading.

Woodring PJ, Meisenhelder J, Johnson SA, Zhou GL, Field J, Shah K, Bladt F, Pawson T, Niki M, Pandolfi PP, Wang JY, Hunter T.

J Cell Biol. 2004 May 24;165(4):493-503. Epub 2004 May 17.


Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II.

Zvara A, Fajardo JE, Escalante M, Cotton G, Muir T, Kirsch KH, Birge RB.

Oncogene. 2001 Feb 22;20(8):951-61.


Abl family kinases and Cbl cooperate with the Nck adaptor to modulate Xenopus development.

Adler CE, Miyoshi-Akiyama T, Aleman LM, Tanaka M, Smith JM, Mayer BJ.

J Biol Chem. 2000 Nov 17;275(46):36472-8.


Phosphorylation of c-Abl by protein kinase Pak2 regulates differential binding of ABI2 and CRK.

Jung JH, Pendergast AM, Zipfel PA, Traugh JA.

Biochemistry. 2008 Jan 22;47(3):1094-104. Epub 2007 Dec 28.


Crk family adaptor proteins trans-activate c-Abl kinase.

Shishido T, Akagi T, Chalmers A, Maeda M, Terada T, Georgescu MM, Hanafusa H.

Genes Cells. 2001 May;6(5):431-40.


Interaction of crk with Myosin-1c participates in fibronectin-induced cell spreading.

Oh H, Kim H, Shin B, Lee KH, Yeo MG, Song WK.

Int J Biol Sci. 2013 Aug 15;9(8):778-91. doi: 10.7150/ijbs.6459. eCollection 2013.


Essential roles of Crk and CrkL in fibroblast structure and motility.

Park TJ, Curran T.

Oncogene. 2014 Oct 23;33(43):5121-32. doi: 10.1038/onc.2013.453. Epub 2013 Oct 28.


The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas.

Roselli S, Wallez Y, Wang L, Vervoort V, Pasquale EB.

Cell Signal. 2010 Nov;22(11):1745-52. doi: 10.1016/j.cellsig.2010.06.015. Epub 2010 Jul 24.


Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes.

Kain KH, Klemke RL.

J Biol Chem. 2001 May 11;276(19):16185-92. Epub 2001 Jan 19.


Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

Sparks AB, Rider JE, Hoffman NG, Fowlkes DM, Quillam LA, Kay BK.

Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1540-4.


Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling.

Heikkinen LS, Kazlauskas A, Melén K, Wagner R, Ziegler T, Julkunen I, Saksela K.

J Biol Chem. 2008 Feb 29;283(9):5719-27. doi: 10.1074/jbc.M707195200. Epub 2007 Dec 28.


Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B.

Rivera GM, Antoku S, Gelkop S, Shin NY, Hanks SK, Pawson T, Mayer BJ.

Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9536-41. Epub 2006 Jun 12.


Abl kinase interacts with and phosphorylates vinexin.

Mitsushima M, Takahashi H, Shishido T, Ueda K, Kioka N.

FEBS Lett. 2006 Jul 24;580(17):4288-95. Epub 2006 Jul 5.


Crk adaptor protein-induced phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration.

Watanabe T, Tsuda M, Makino Y, Konstantinou T, Nishihara H, Majima T, Minami A, Feller SM, Tanaka S.

Cell Res. 2009 May;19(5):638-50. doi: 10.1038/cr.2009.40.


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