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Items: 1 to 20 of 195

1.

An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.

Fujita N, Hayashi-Nishino M, Fukumoto H, Omori H, Yamamoto A, Noda T, Yoshimori T.

Mol Biol Cell. 2008 Nov;19(11):4651-9. doi: 10.1091/mbc.E08-03-0312. Epub 2008 Sep 3.

2.

Atg4B(C74A) hampers autophagosome closure: a useful protein for inhibiting autophagy.

Fujita N, Noda T, Yoshimori T.

Autophagy. 2009 Jan;5(1):88-9.

PMID:
19104152
3.

The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy.

Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T.

Mol Biol Cell. 2008 May;19(5):2092-100. doi: 10.1091/mbc.E07-12-1257. Epub 2008 Mar 5.

4.

Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation.

Mauthe M, Jacob A, Freiberger S, Hentschel K, Stierhof YD, Codogno P, Proikas-Cezanne T.

Autophagy. 2011 Dec;7(12):1448-61.

5.
6.

Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection.

Kuang E, Okumura CY, Sheffy-Levin S, Varsano T, Shu VC, Qi J, Niesman IR, Yang HJ, López-Otín C, Yang WY, Reed JC, Broday L, Nizet V, Ronai ZA.

PLoS Genet. 2012;8(10):e1003007. doi: 10.1371/journal.pgen.1003007. Epub 2012 Oct 18.

7.

Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis.

Nakatogawa H, Ishii J, Asai E, Ohsumi Y.

Autophagy. 2012 Feb 1;8(2):177-86. doi: 10.4161/auto.8.2.18373. Epub 2012 Feb 1.

PMID:
22240591
8.

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation.

Polson HE, de Lartigue J, Rigden DJ, Reedijk M, Urbé S, Clague MJ, Tooze SA.

Autophagy. 2010 May;6(4):506-22. doi: 10.4161/auto.6.4.11863. Epub 2010 May 16.

PMID:
20505359
9.

Vaccinia virus leads to ATG12–ATG3 conjugation and deficiency in autophagosome formation.

Moloughney JG, Monken CE, Tao H, Zhang H, Thomas JD, Lattime EC, Jin S.

Autophagy. 2011 Dec;7(12):1434-47.

10.
11.

A role for Atg8-PE deconjugation in autophagosome biogenesis.

Nair U, Yen WL, Mari M, Cao Y, Xie Z, Baba M, Reggiori F, Klionsky DJ.

Autophagy. 2012 May 1;8(5):780-93. doi: 10.4161/auto.19385. Epub 2012 May 1.

13.

Atg4 plays an important role in efficient expansion of autophagic isolation membranes by cleaving lipidated Atg8 in Saccharomyces cerevisiae.

Hirata E, Ohya Y, Suzuki K.

PLoS One. 2017 Jul 13;12(7):e0181047. doi: 10.1371/journal.pone.0181047. eCollection 2017.

14.

Autophagosomes in GFP-LC3 Transgenic Mice.

Mizushima N, Kuma A.

Methods Mol Biol. 2008;445:119-24. doi: 10.1007/978-1-59745-157-4_7.

PMID:
18425446
15.

The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation.

Tanida I, Yamasaki M, Komatsu M, Ueno T.

Autophagy. 2012 Jan;8(1):88-97. doi: 10.4161/auto.8.1.18339. Epub 2012 Jan 1.

PMID:
22170151
16.

Visualization of Atg3 during autophagosome formation in Saccharomyces cerevisiae.

Ngu M, Hirata E, Suzuki K.

J Biol Chem. 2015 Mar 27;290(13):8146-53. doi: 10.1074/jbc.M114.626952. Epub 2015 Feb 2.

17.

The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers.

Kumanomidou T, Mizushima T, Komatsu M, Suzuki A, Tanida I, Sou YS, Ueno T, Kominami E, Tanaka K, Yamane T.

J Mol Biol. 2006 Jan 27;355(4):612-8. Epub 2005 Nov 28.

PMID:
16325851
18.

The evolutionarily conserved interaction between LC3 and p62 selectively mediates autophagy-dependent degradation of mutant huntingtin.

Tung YT, Hsu WM, Lee H, Huang WP, Liao YF.

Cell Mol Neurobiol. 2010 Jul;30(5):795-806. doi: 10.1007/s10571-010-9507-y. Epub 2010 Mar 5.

PMID:
20204693
19.

Differing susceptibility to autophagic degradation of two LC3-binding proteins: SQSTM1/p62 and TBC1D25/OATL1.

Hirano S, Uemura T, Annoh H, Fujita N, Waguri S, Itoh T, Fukuda M.

Autophagy. 2016;12(2):312-26. doi: 10.1080/15548627.2015.1124223.

20.

E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I.

Gao W, Chen Z, Wang W, Stang MT.

PLoS One. 2013 Sep 4;8(9):e73229. doi: 10.1371/journal.pone.0073229. eCollection 2013.

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