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Items: 1 to 20 of 114

1.
2.

Regulation of the MtrC-MtrD-MtrE efflux-pump system modulates the in vivo fitness of Neisseria gonorrhoeae.

Warner DM, Folster JP, Shafer WM, Jerse AE.

J Infect Dis. 2007 Dec 15;196(12):1804-12. doi: 10.1086/522964.

PMID:
18190261
3.

A novel mechanism of high-level, broad-spectrum antibiotic resistance caused by a single base pair change in Neisseria gonorrhoeae.

Ohneck EA, Zalucki YM, Johnson PJ, Dhulipala V, Golparian D, Unemo M, Jerse AE, Shafer WM.

MBio. 2011 Sep 20;2(5). pii: e00187-11. doi: 10.1128/mBio.00187-11. Print 2011.

5.

Decreased azithromycin susceptibility of Neisseria gonorrhoeae due to mtrR mutations.

Zarantonelli L, Borthagaray G, Lee EH, Shafer WM.

Antimicrob Agents Chemother. 1999 Oct;43(10):2468-72.

6.

Loss-of-function mutations in the mtr efflux system of Neisseria gonorrhoeae.

Veal WL, Yellen A, Balthazar JT, Pan W, Spratt BG, Shafer WM.

Microbiology. 1998 Mar;144 ( Pt 3):621-7.

PMID:
9534233
7.

A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection.

Jerse AE, Sharma ND, Simms AN, Crow ET, Snyder LA, Shafer WM.

Infect Immun. 2003 Oct;71(10):5576-82.

8.

Characterization of the MacA-MacB efflux system in Neisseria gonorrhoeae.

Rouquette-Loughlin CE, Balthazar JT, Shafer WM.

J Antimicrob Chemother. 2005 Nov;56(5):856-60. Epub 2005 Sep 14.

PMID:
16162665
9.
10.
11.

MtrR modulates rpoH expression and levels of antimicrobial resistance in Neisseria gonorrhoeae.

Folster JP, Johnson PJ, Jackson L, Dhulipali V, Dyer DW, Shafer WM.

J Bacteriol. 2009 Jan;191(1):287-97. doi: 10.1128/JB.01165-08. Epub 2008 Oct 31.

12.

Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3:6:3.

Janganan TK, Bavro VN, Zhang L, Matak-Vinkovic D, Barrera NP, Venien-Bryan C, Robinson CV, Borges-Walmsley MI, Walmsley AR.

J Biol Chem. 2011 Jul 29;286(30):26900-12. doi: 10.1074/jbc.M111.246595. Epub 2011 May 24.

13.
14.

Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon.

Rouquette-Loughlin CE, Zalucki YM, Dhulipala VL, Balthazar JT, Doyle RG, Nicholas RA, Begum AA, Raterman EL, Jerse AE, Shafer WM.

MBio. 2017 Apr 11;8(2). pii: e00449-17. doi: 10.1128/mBio.00449-17.

15.

Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system.

Hagman KE, Pan W, Spratt BG, Balthazar JT, Judd RC, Shafer WM.

Microbiology. 1995 Mar;141 ( Pt 3):611-22.

PMID:
7711899
16.

Differential regulation of ponA and pilMNOPQ expression by the MtrR transcriptional regulatory protein in Neisseria gonorrhoeae.

Folster JP, Dhulipala V, Nicholas RA, Shafer WM.

J Bacteriol. 2007 Jul;189(13):4569-77. Epub 2007 May 4.

17.

The MtrR repressor binds the DNA sequence between the mtrR and mtrC genes of Neisseria gonorrhoeae.

Lucas CE, Balthazar JT, Hagman KE, Shafer WM.

J Bacteriol. 1997 Jul;179(13):4123-8.

18.

Mutations causing in vitro resistance to azithromycin in Neisseria gonorrhoeae.

Johnson SR, Sandul AL, Parekh M, Wang SA, Knapp JS, Trees DL.

Int J Antimicrob Agents. 2003 May;21(5):414-9.

PMID:
12727073
19.

Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner.

Janganan TK, Zhang L, Bavro VN, Matak-Vinkovic D, Barrera NP, Burton MF, Steel PG, Robinson CV, Borges-Walmsley MI, Walmsley AR.

J Biol Chem. 2011 Feb 18;286(7):5484-93. doi: 10.1074/jbc.M110.187658. Epub 2010 Nov 29.

20.

Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump.

Janganan TK, Bavro VN, Zhang L, Borges-Walmsley MI, Walmsley AR.

Mol Microbiol. 2013 May;88(3):590-602. doi: 10.1111/mmi.12211. Epub 2013 Apr 9.

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