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Items: 1 to 20 of 95

1.

The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.

Hansson Petersen CA, Alikhani N, Behbahani H, Wiehager B, Pavlov PF, Alafuzoff I, Leinonen V, Ito A, Winblad B, Glaser E, Ankarcrona M.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13145-50. doi: 10.1073/pnas.0806192105. Epub 2008 Aug 29.

2.

Further evidence on mitochondrial targeting of β-amyloid and specificity of β-amyloid-induced mitotoxicity in neurons.

Tillement L, Lecanu L, Papadopoulos V.

Neurodegener Dis. 2011;8(5):331-44. doi: 10.1159/000323264. Epub 2011 Feb 11.

PMID:
21311166
3.

Chronic exposure to sub-lethal beta-amyloid (Abeta) inhibits the import of nuclear-encoded proteins to mitochondria in differentiated PC12 cells.

Sirk D, Zhu Z, Wadia JS, Shulyakova N, Phan N, Fong J, Mills LR.

J Neurochem. 2007 Dec;103(5):1989-2003. Epub 2007 Sep 13.

4.

Mitochondrial import and degradation of amyloid-β peptide.

Pinho CM, Teixeira PF, Glaser E.

Biochim Biophys Acta. 2014 Jul;1837(7):1069-74. doi: 10.1016/j.bbabio.2014.02.007. Epub 2014 Feb 18. Review.

5.

Amyloid-β and the failure to form mitochondrial cristae: a biomimetic study involving artificial membranes.

Khalifat N, Puff N, Dliaa M, Angelova MI.

J Alzheimers Dis. 2012;28(1):33-48. doi: 10.3233/JAD-2011-110389.

PMID:
21987591
6.

Aging promotes amyloid-β peptide induced mitochondrial dysfunctions in rat brain: a molecular link between aging and Alzheimer's disease.

Sinha M, Behera P, Bhowmick P, Banerjee K, Basu S, Chakrabarti S.

J Alzheimers Dis. 2011;27(4):753-65. doi: 10.3233/JAD-2011-110686.

PMID:
21876248
7.

Interaction between NH(2)-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deterioration.

Amadoro G, Corsetti V, Atlante A, Florenzano F, Capsoni S, Bussani R, Mercanti D, Calissano P.

Neurobiol Aging. 2012 Apr;33(4):833.e1-25. doi: 10.1016/j.neurobiolaging.2011.08.001. Epub 2011 Sep 29.

PMID:
21958963
8.

Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/Bcl(XL)-regulated mitochondrial apoptotic pathway.

Zeng KW, Wang XM, Ko H, Kwon HC, Cha JW, Yang HO.

Eur J Pharmacol. 2011 Dec 15;672(1-3):45-55. doi: 10.1016/j.ejphar.2011.09.177. Epub 2011 Sep 29.

PMID:
21978835
10.

Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein.

Pavlov PF, Wiehager B, Sakai J, Frykman S, Behbahani H, Winblad B, Ankarcrona M.

FASEB J. 2011 Jan;25(1):78-88. doi: 10.1096/fj.10-157230. Epub 2010 Sep 10.

PMID:
20833873
11.

Protein import into mitochondria.

Paschen SA, Neupert W.

IUBMB Life. 2001 Sep-Nov;52(3-5):101-12. Review.

12.

Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death.

Cha MY, Han SH, Son SM, Hong HS, Choi YJ, Byun J, Mook-Jung I.

PLoS One. 2012;7(4):e34929. doi: 10.1371/journal.pone.0034929. Epub 2012 Apr 13.

13.

Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure.

Rhein V, Giese M, Baysang G, Meier F, Rao S, Schulz KL, Hamburger M, Eckert A.

PLoS One. 2010 Aug 24;5(8):e12359. doi: 10.1371/journal.pone.0012359.

14.

Effect of β-amyloid (25-35) on mitochondrial function and expression of mitochondrial permeability transition pore proteins in rat hippocampal neurons.

Ren R, Zhang Y, Li B, Wu Y, Li B.

J Cell Biochem. 2011 May;112(5):1450-7. doi: 10.1002/jcb.23062.

PMID:
21321998
15.

Intracellular localization of amyloid-β peptide in SH-SY5Y neuroblastoma cells.

Zheng L, Calvo-Garrido J, Hallbeck M, Hultenby K, Marcusson J, Cedazo-Minguez A, Terman A.

J Alzheimers Dis. 2013;37(4):713-33. doi: 10.3233/JAD-122455.

PMID:
23948913
16.
17.

Mortalin overexpression attenuates beta-amyloid-induced neurotoxicity in SH-SY5Y cells.

Qu M, Zhou Z, Xu S, Chen C, Yu Z, Wang D.

Brain Res. 2011 Jan 12;1368:336-45. doi: 10.1016/j.brainres.2010.10.068. Epub 2010 Oct 23.

PMID:
20974113
18.

Biogenesis of the protein import channel Tom40 of the mitochondrial outer membrane: intermembrane space components are involved in an early stage of the assembly pathway.

Wiedemann N, Truscott KN, Pfannschmidt S, Guiard B, Meisinger C, Pfanner N.

J Biol Chem. 2004 Apr 30;279(18):18188-94. Epub 2004 Feb 20.

19.

Mitochondria and Alzheimer's disease: amyloid-beta peptide uptake and degradation by the presequence protease, hPreP.

Alikhani N, Ankarcrona M, Glaser E.

J Bioenerg Biomembr. 2009 Oct;41(5):447-51. doi: 10.1007/s10863-009-9244-4. Review.

PMID:
19798557
20.

Amyloid precursor protein and amyloid beta-peptide bind to ATP synthase and regulate its activity at the surface of neural cells.

Schmidt C, Lepsverdize E, Chi SL, Das AM, Pizzo SV, Dityatev A, Schachner M.

Mol Psychiatry. 2008 Oct;13(10):953-69. Epub 2007 Aug 28.

PMID:
17726461

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