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Items: 1 to 20 of 148

1.

Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer.

Bernard-Pierrot I, Gruel N, Stransky N, Vincent-Salomon A, Reyal F, Raynal V, Vallot C, Pierron G, Radvanyi F, Delattre O.

Cancer Res. 2008 Sep 1;68(17):7165-75. doi: 10.1158/0008-5472.CAN-08-1360.

2.

PPAPDC1B and WHSC1L1 are common drivers of the 8p11-12 amplicon, not only in breast tumors but also in pancreatic adenocarcinomas and lung tumors.

Mahmood SF, Gruel N, Nicolle R, Chapeaublanc E, Delattre O, Radvanyi F, Bernard-Pierrot I.

Am J Pathol. 2013 Nov;183(5):1634-1644. doi: 10.1016/j.ajpath.2013.07.028. Epub 2013 Sep 17.

PMID:
24051013
3.

Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer.

Yang ZQ, Streicher KL, Ray ME, Abrams J, Ethier SP.

Cancer Res. 2006 Dec 15;66(24):11632-43.

4.

A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes.

Garcia MJ, Pole JC, Chin SF, Teschendorff A, Naderi A, Ozdag H, Vias M, Kranjac T, Subkhankulova T, Paish C, Ellis I, Brenton JD, Edwards PA, Caldas C.

Oncogene. 2005 Aug 4;24(33):5235-45.

PMID:
15897872
5.

Comprehensive profiling of 8p11-12 amplification in breast cancer.

Gelsi-Boyer V, Orsetti B, Cervera N, Finetti P, Sircoulomb F, Rougé C, Lasorsa L, Letessier A, Ginestier C, Monville F, Esteyriès S, Adélaïde J, Esterni B, Henry C, Ethier SP, Bibeau F, Mozziconacci MJ, Charafe-Jauffret E, Jacquemier J, Bertucci F, Birnbaum D, Theillet C, Chaffanet M.

Mol Cancer Res. 2005 Dec;3(12):655-67.

6.

Genomic and expression analysis of the 8p11-12 amplicon in human breast cancer cell lines.

Ray ME, Yang ZQ, Albertson D, Kleer CG, Washburn JG, Macoska JA, Ethier SP.

Cancer Res. 2004 Jan 1;64(1):40-7.

7.

Chromosome 8 BAC array comparative genomic hybridization and expression analysis identify amplification and overexpression of TRMT12 in breast cancer.

Rodriguez V, Chen Y, Elkahloun A, Dutra A, Pak E, Chandrasekharappa S.

Genes Chromosomes Cancer. 2007 Jul;46(7):694-707.

PMID:
17440925
8.

Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progression.

Yao J, Weremowicz S, Feng B, Gentleman RC, Marks JR, Gelman R, Brennan C, Polyak K.

Cancer Res. 2006 Apr 15;66(8):4065-78.

9.

Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer.

Dahl E, Kristiansen G, Gottlob K, Klaman I, Ebner E, Hinzmann B, Hermann K, Pilarsky C, Dürst M, Klinkhammer-Schalke M, Blaszyk H, Knuechel R, Hartmann A, Rosenthal A, Wild PJ.

Clin Cancer Res. 2006 Jul 1;12(13):3950-60.

10.

Gene amplification and overexpression of protein phosphatase 1alpha in oral squamous cell carcinoma cell lines.

Hsu LC, Huang X, Seasholtz S, Potter DM, Gollin SM.

Oncogene. 2006 Sep 7;25(40):5517-26. Epub 2006 Apr 17.

PMID:
16619035
11.

Genomic organization of the 8p11-p12 amplicon in three breast cancer cell lines.

Yang ZQ, Albertson D, Ethier SP.

Cancer Genet Cytogenet. 2004 Nov;155(1):57-62.

PMID:
15527903
12.

Transforming properties of 8p11-12 amplified genes in human breast cancer.

Yang ZQ, Liu G, Bollig-Fischer A, Giroux CN, Ethier SP.

Cancer Res. 2010 Nov 1;70(21):8487-97. doi: 10.1158/0008-5472.CAN-10-1013. Epub 2010 Oct 12.

13.

Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines.

Arriola E, Marchio C, Tan DS, Drury SC, Lambros MB, Natrajan R, Rodriguez-Pinilla SM, Mackay A, Tamber N, Fenwick K, Jones C, Dowsett M, Ashworth A, Reis-Filho JS.

Lab Invest. 2008 May;88(5):491-503. doi: 10.1038/labinvest.2008.19. Epub 2008 Mar 10.

14.

Genetic profiling of chromosome 1 in breast cancer: mapping of regions of gains and losses and identification of candidate genes on 1q.

Orsetti B, Nugoli M, Cervera N, Lasorsa L, Chuchana P, Rougé C, Ursule L, Nguyen C, Bibeau F, Rodriguez C, Theillet C.

Br J Cancer. 2006 Nov 20;95(10):1439-47. Epub 2006 Oct 24.

15.

Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones.

Clark J, Edwards S, John M, Flohr P, Gordon T, Maillard K, Giddings I, Brown C, Bagherzadeh A, Campbell C, Shipley J, Wooster R, Cooper CS.

Genes Chromosomes Cancer. 2002 May;34(1):104-14.

PMID:
11921288
16.

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas.

Reis-Filho JS, Simpson PT, Turner NC, Lambros MB, Jones C, Mackay A, Grigoriadis A, Sarrio D, Savage K, Dexter T, Iravani M, Fenwick K, Weber B, Hardisson D, Schmitt FC, Palacios J, Lakhani SR, Ashworth A.

Clin Cancer Res. 2006 Nov 15;12(22):6652-62.

17.

HTPAP gene on chromosome 8p is a candidate metastasis suppressor for human hepatocellular carcinoma.

Wu X, Jia HL, Wang YF, Ren N, Ye QH, Sun HC, Wang L, Liu YK, Tang ZY, Qin LX.

Oncogene. 2006 Mar 16;25(12):1832-40.

PMID:
16261160
18.
19.

Amplification and overexpression of Elongin C gene discovered in prostate cancer by cDNA microarrays.

Porkka K, Saramäki O, Tanner M, Visakorpi T.

Lab Invest. 2002 May;82(5):629-37.

PMID:
12004003
20.

Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7.

Webster RJ, Giles KM, Price KJ, Zhang PM, Mattick JS, Leedman PJ.

J Biol Chem. 2009 Feb 27;284(9):5731-41. doi: 10.1074/jbc.M804280200. Epub 2008 Dec 10.

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