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Items: 1 to 20 of 134

1.

Role of serum- and glucocorticoid-inducible kinase SGK1 in glucocorticoid regulation of renal electrolyte excretion and blood pressure.

Boini KM, Nammi S, Grahammer F, Osswald H, Kuhl D, Lang F.

Kidney Blood Press Res. 2008;31(4):280-9. doi: 10.1159/000151666. Epub 2008 Aug 28.

2.

Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1.

Huang DY, Boini KM, Friedrich B, Metzger M, Just L, Osswald H, Wulff P, Kuhl D, Vallon V, Lang F.

Am J Physiol Regul Integr Comp Physiol. 2006 Apr;290(4):R935-44. Epub 2005 Nov 10.

3.

Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet.

Huang DY, Boini KM, Osswald H, Friedrich B, Artunc F, Ullrich S, Rajamanickam J, Palmada M, Wulff P, Kuhl D, Vallon V, Lang F.

Am J Physiol Renal Physiol. 2006 Dec;291(6):F1264-73. Epub 2006 Sep 26.

4.

SGK1 as a determinant of kidney function and salt intake in response to mineralocorticoid excess.

Vallon V, Huang DY, Grahammer F, Wyatt AW, Osswald H, Wulff P, Kuhl D, Lang F.

Am J Physiol Regul Integr Comp Physiol. 2005 Aug;289(2):R395-R401.

5.

Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC.

Bhandaru M, Kempe DS, Rotte A, Rexhepaj R, Kuhl D, Lang F.

Am J Physiol Regul Integr Comp Physiol. 2009 Sep;297(3):R571-5. doi: 10.1152/ajpregu.00070.2009. Epub 2009 Jun 3.

6.

Renal function of gene-targeted mice lacking both SGK1 and SGK3.

Grahammer F, Artunc F, Sandulache D, Rexhepaj R, Friedrich B, Risler T, McCormick JA, Dawson K, Wang J, Pearce D, Wulff P, Kuhl D, Lang F.

Am J Physiol Regul Integr Comp Physiol. 2006 Apr;290(4):R945-50.

7.

Deranged Kv channel regulation in fibroblasts from mice lacking the serum and glucocorticoid inducible kinase SGK1.

Shumilina E, Lampert A, Lupescu A, Myssina S, Strutz-Seebohm N, Henke G, Grahammer F, Wulff P, Kuhl D, Lang F.

J Cell Physiol. 2005 Jul;204(1):87-98.

PMID:
15605386
8.

Impaired mast cell activation in gene-targeted mice lacking the serum- and glucocorticoid-inducible kinase SGK1.

Sobiesiak M, Shumilina E, Lam RS, Wölbing F, Matzner N, Kaesler S, Zemtsova IM, Lupescu A, Zahir N, Kuhl D, Schaller M, Biedermann T, Lang F.

J Immunol. 2009 Oct 1;183(7):4395-402. doi: 10.4049/jimmunol.0803017. Epub 2009 Sep 11.

9.

Impaired renal Na(+) retention in the sgk1-knockout mouse.

Wulff P, Vallon V, Huang DY, Völkl H, Yu F, Richter K, Jansen M, Schlünz M, Klingel K, Loffing J, Kauselmann G, Bösl MR, Lang F, Kuhl D.

J Clin Invest. 2002 Nov;110(9):1263-8.

10.

Responses to diuretic treatment in gene-targeted mice lacking serum- and glucocorticoid-inducible kinase 1.

Artunc F, Ebrahim A, Siraskar B, Nasir O, Rexhepaj R, Amann K, Friedrich B, Risler T, Lang F.

Kidney Blood Press Res. 2009;32(2):119-27. doi: 10.1159/000214439. Epub 2009 Apr 25.

11.

Impaired regulation of renal K+ elimination in the sgk1-knockout mouse.

Huang DY, Wulff P, Völkl H, Loffing J, Richter K, Kuhl D, Lang F, Vallon V.

J Am Soc Nephrol. 2004 Apr;15(4):885-91.

12.

Role of maternal glucocorticoid inducible kinase SGK1 in fetal programming of blood pressure in response to prenatal diet.

Rexhepaj R, Boini KM, Huang DY, Amann K, Artunc F, Wang K, Brosens JJ, Kuhl D, Lang F.

Am J Physiol Regul Integr Comp Physiol. 2008 Jun;294(6):R2008-13. doi: 10.1152/ajpregu.00737.2007. Epub 2008 Mar 26.

13.

Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion.

Ullrich S, Berchtold S, Ranta F, Seebohm G, Henke G, Lupescu A, Mack AF, Chao CM, Su J, Nitschke R, Alexander D, Friedrich B, Wulff P, Kuhl D, Lang F.

Diabetes. 2005 Apr;54(4):1090-9.

14.

Gene regulation of ENaC subunits by serum- and glucocorticoid-inducible kinase-1.

Boyd C, Náray-Fejes-Tóth A.

Am J Physiol Renal Physiol. 2005 Mar;288(3):F505-12. Epub 2004 Nov 9.

15.

Serum- and glucocorticoid-inducible kinase 1 in doxorubicin-induced nephrotic syndrome.

Artunc F, Nasir O, Amann K, Boini KM, Häring HU, Risler T, Lang F.

Am J Physiol Renal Physiol. 2008 Dec;295(6):F1624-34. doi: 10.1152/ajprenal.00032.2008. Epub 2008 Sep 3.

16.

Therapeutic potential of serum and glucocorticoid inducible kinase inhibition.

Lang F, Voelkl J.

Expert Opin Investig Drugs. 2013 Jun;22(6):701-14. doi: 10.1517/13543784.2013.778971. Epub 2013 Mar 19. Review.

PMID:
23506284
17.

EMD638683, a novel SGK inhibitor with antihypertensive potency.

Ackermann TF, Boini KM, Beier N, Scholz W, Fuchss T, Lang F.

Cell Physiol Biochem. 2011;28(1):137-46. doi: 10.1159/000331722. Epub 2011 Aug 16.

18.

Serum- and glucocorticoid-inducible kinase 1 mediates salt sensitivity of glucose tolerance.

Boini KM, Hennige AM, Huang DY, Friedrich B, Palmada M, Boehmer C, Grahammer F, Artunc F, Ullrich S, Avram D, Osswald H, Wulff P, Kuhl D, Vallon V, Häring HU, Lang F.

Diabetes. 2006 Jul;55(7):2059-66.

19.

SGK1 is not required for regulation of colonic ENaC activity.

Rexhepaj R, Artunc F, Grahammer F, Nasir O, Sandu C, Friedrich B, Kuhl D, Lang F.

Pflugers Arch. 2006 Oct;453(1):97-105. Epub 2006 Aug 8.

PMID:
16897044
20.

Inducible kidney-specific Sgk1 knockout mice show a salt-losing phenotype.

Faresse N, Lagnaz D, Debonneville A, Ismailji A, Maillard M, Fejes-Toth G, Náray-Fejes-Tóth A, Staub O.

Am J Physiol Renal Physiol. 2012 Apr 15;302(8):F977-85. doi: 10.1152/ajprenal.00535.2011. Epub 2012 Feb 1.

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