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Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial.

Feig DI, Soletsky B, Johnson RJ.

JAMA. 2008 Aug 27;300(8):924-32. doi: 10.1001/jama.300.8.924.


Pharmacotherapy for hyperuricemia in hypertensive patients.

Gois PH, Souza ER.

Cochrane Database Syst Rev. 2013 Jan 31;(1):CD008652. doi: 10.1002/14651858.CD008652.pub2. Review. Update in: Cochrane Database Syst Rev. 2017 Apr 13;4:CD008652.


Pharmacotherapy for hyperuricemia in hypertensive patients.

Gois PHF, Souza ERM.

Cochrane Database Syst Rev. 2017 Apr 13;4:CD008652. doi: 10.1002/14651858.CD008652.pub3. Review.


Effects of xanthine oxidase inhibitors on renal function and blood pressure in hypertensive patients with hyperuricemia.

Kohagura K, Tana T, Higa A, Yamazato M, Ishida A, Nagahama K, Sakima A, Iseki K, Ohya Y.

Hypertens Res. 2016 Aug;39(8):593-7. doi: 10.1038/hr.2016.37. Epub 2016 Apr 14.


Allopurinol initiation and change in blood pressure in older adults with hypertension.

Beattie CJ, Fulton RL, Higgins P, Padmanabhan S, McCallum L, Walters MR, Dominiczak AF, Touyz RM, Dawson J.

Hypertension. 2014 Nov;64(5):1102-7. doi: 10.1161/HYPERTENSIONAHA.114.03953. Epub 2014 Aug 18.


Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level.

Siu YP, Leung KT, Tong MK, Kwan TH.

Am J Kidney Dis. 2006 Jan;47(1):51-9.


Uric acid reduction rectifies prehypertension in obese adolescents.

Soletsky B, Feig DI.

Hypertension. 2012 Nov;60(5):1148-56. doi: 10.1161/HYPERTENSIONAHA.112.196980. Epub 2012 Sep 24.


Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) Study.

Givertz MM, Anstrom KJ, Redfield MM, Deswal A, Haddad H, Butler J, Tang WH, Dunlap ME, LeWinter MM, Mann DL, Felker GM, O'Connor CM, Goldsmith SR, Ofili EO, Saltzberg MT, Margulies KB, Cappola TP, Konstam MA, Semigran MJ, McNulty SE, Lee KL, Shah MR, Hernandez AF; NHLBI Heart Failure Clinical Research Network.

Circulation. 2015 May 19;131(20):1763-71. doi: 10.1161/CIRCULATIONAHA.114.014536. Epub 2015 Apr 14.


Effect on blood pressure of combined inhibition of endothelin-converting enzyme and neutral endopeptidase with daglutril in patients with type 2 diabetes who have albuminuria: a randomised, crossover, double-blind, placebo-controlled trial.

Parvanova A, van der Meer IM, Iliev I, Perna A, Gaspari F, Trevisan R, Bossi A, Remuzzi G, Benigni A, Ruggenenti P; Daglutril in Diabetic Nephropathy Study Group.

Lancet Diabetes Endocrinol. 2013 Sep;1(1):19-27. doi: 10.1016/S2213-8587(13)70029-9. Epub 2013 Jun 13.


The effect of the addition of allopurinol on blood pressure control in African Americans treated with a thiazide-like diuretic.

Segal MS, Srinivas TR, Mohandas R, Shuster JJ, Wen X, Whidden E, Tantravahi J, Johnson RJ.

J Am Soc Hypertens. 2015 Aug;9(8):610-619.e1. doi: 10.1016/j.jash.2015.05.009. Epub 2015 May 22.


Effect of allopurinol on blood pressure: a systematic review and meta-analysis.

Agarwal V, Hans N, Messerli FH.

J Clin Hypertens (Greenwich). 2013 Jun;15(6):435-42. doi: 10.1111/j.1751-7176.2012.00701.x. Epub 2012 Aug 20. Review.


A multicenter, randomized, double-blind comparison of the efficacy and safety of irbesartan and enalapril in adults with mild to moderate essential hypertension, as assessed by ambulatory blood pressure monitoring: the MAPAVEL Study (Monitorización Ambulatoria Presión Arterial APROVEL).

Coca A, Calvo C, García-Puig J, Gil-Extremera B, Aguilera MT, de la Sierra A, Martín-Hidalgo A, Marín R; MAPAVEL Investigators (Monitorizacíon Ambulatoria Presión Arterial APROVEL).

Clin Ther. 2002 Jan;24(1):126-38.


Randomized controlled trial of febuxostat versus allopurinol or placebo in individuals with higher urinary uric acid excretion and calcium stones.

Goldfarb DS, MacDonald PA, Gunawardhana L, Chefo S, McLean L.

Clin J Am Soc Nephrol. 2013 Nov;8(11):1960-7. doi: 10.2215/CJN.01760213. Epub 2013 Aug 8.


Benefits of Allopurinol Treatment on Blood Pressure and Renal Function in Patients with Early Stage of Chronic Kidney Disease.

Satirapoj B, Wirajit O, Burata A, Supasyndh O, Ruangkanchanasetr P.

J Med Assoc Thai. 2015 Dec;98(12):1155-61.


Allopurinol enhances the blood pressure lowering effect of enalapril in children with hyperuricemic essential hypertension.

Assadi F.

J Nephrol. 2014 Feb;27(1):51-6. doi: 10.1007/s40620-013-0009-0. Epub 2013 Dec 13.


The alkalizer citrate reduces serum uric Acid levels and improves renal function in hyperuricemic patients treated with the xanthine oxidase inhibitor allopurinol.

Saito J, Matsuzawa Y, Ito H, Omura M, Ito Y, Yoshimura K, Yajima Y, Kino T, Nishikawa T.

Endocr Res. 2010;35(4):145-54. doi: 10.3109/07435800.2010.497178.


A randomized study of allopurinol on endothelial function and estimated glomular filtration rate in asymptomatic hyperuricemic subjects with normal renal function.

Kanbay M, Huddam B, Azak A, Solak Y, Kadioglu GK, Kirbas I, Duranay M, Covic A, Johnson RJ.

Clin J Am Soc Nephrol. 2011 Aug;6(8):1887-94. doi: 10.2215/CJN.11451210. Epub 2011 Jul 22. Erratum in: Clin J Am Soc Nephrol. 2011 Dec;6(12):2901-2.


Ambulatory versus clinic blood pressure for the assessment of anti hypertensive efficacy in clinical trials: insights from the Val-Syst Study.

Palatini P, Dorigatti F, Mugellini A, Spagnuolo V, Varì N, Ferrara R, Bertocchi F.

Clin Ther. 2004 Sep;26(9):1436-45.


Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension. Systolic Hypertension in Europe Trial Investigators.

Staessen JA, Thijs L, Fagard R, O'Brien ET, Clement D, de Leeuw PW, Mancia G, Nachev C, Palatini P, Parati G, Tuomilehto J, Webster J.

JAMA. 1999 Aug 11;282(6):539-46.


An allopurinol-controlled, multicenter, randomized, double-blind, parallel between-group, comparative study of febuxostat in Chinese patients with gout and hyperuricemia.

Huang X, Du H, Gu J, Zhao D, Jiang L, Li X, Zuo X, Liu Y, Li Z, Li X, Zhu P, Li J, Zhang Z, Huang A, Zhang Y, Bao C.

Int J Rheum Dis. 2014 Jul;17(6):679-86. doi: 10.1111/1756-185X.12266. Epub 2014 Jan 28.


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