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Items: 1 to 20 of 101

1.

Human beta-defensin 3 binds to hemagglutinin B (rHagB), a non-fimbrial adhesin from Porphyromonas gingivalis, and attenuates a pro-inflammatory cytokine response.

Pingel LC, Kohlgraf KG, Hansen CJ, Eastman CG, Dietrich DE, Burnell KK, Srikantha RN, Xiao X, Bélanger M, Progulske-Fox A, Cavanaugh JE, Guthmiller JM, Johnson GK, Joly S, Kurago ZB, Dawson DV, Brogden KA.

Immunol Cell Biol. 2008 Nov-Dec;86(8):643-9. doi: 10.1038/icb.2008.56. Epub 2008 Aug 19.

PMID:
18711400
2.

Defensins attenuate cytokine responses yet enhance antibody responses to Porphyromonas gingivalis adhesins in mice.

Kohlgraf KG, Ackermann A, Lu X, Burnell K, Bélanger M, Cavanaugh JE, Xie H, Progulske-Fox A, Brogden KA.

Future Microbiol. 2010 Jan;5(1):115-25. doi: 10.2217/fmb.09.107.

3.

Human alpha- and beta-defensins bind to immobilized adhesins from Porphyromonas gingivalis.

Dietrich DE, Xiao X, Dawson DV, Bélanger M, Xie H, Progulske-Fox A, Brogden KA.

Infect Immun. 2008 Dec;76(12):5714-20. doi: 10.1128/IAI.00997-08. Epub 2008 Oct 13.

4.

Human β-defensin-3 alters, but does not inhibit, the binding of Porphyromonas gingivalis haemagglutinin B to the surface of human dendritic cells.

Van Hemert JR, Recker EN, Dietrich D, Progulske-Fox A, Kurago ZB, Walters KS, Cavanaugh JE, Brogden KA.

Int J Antimicrob Agents. 2012 Jul;40(1):75-9. doi: 10.1016/j.ijantimicag.2012.03.007. Epub 2012 May 9.

5.

Innate immune defenses: finding a new way to calm the storm.

McGillivary G, Bakaletz LO.

Immunol Cell Biol. 2008 Nov-Dec;86(8):639-40. doi: 10.1038/icb.2008.66. Epub 2008 Sep 16. No abstract available.

7.

TLR4 signaling via MyD88 and TRIF differentially shape the CD4+ T cell response to Porphyromonas gingivalis hemagglutinin B.

Gaddis DE, Michalek SM, Katz J.

J Immunol. 2011 May 15;186(10):5772-83. doi: 10.4049/jimmunol.1003192. Epub 2011 Apr 15.

8.

Requirement of TLR4 and CD14 in dendritic cell activation by Hemagglutinin B from Porphyromonas gingivalis.

Gaddis DE, Michalek SM, Katz J.

Mol Immunol. 2009 Aug;46(13):2493-504. doi: 10.1016/j.molimm.2009.05.022. Epub 2009 Jun 21.

9.

Human β-defensin-3 alleviates the progression of atherosclerosis accelerated by Porphyromonas gingivalis lipopolysaccharide.

Li L, Bian T, Lyu J, Cui D, Lei L, Yan F.

Int Immunopharmacol. 2016 Sep;38:204-13. doi: 10.1016/j.intimp.2016.06.003. Epub 2016 Jun 10.

PMID:
27289299
10.

Differential and coordinated expression of defensins and cytokines by gingival epithelial cells and dendritic cells in response to oral bacteria.

Yin L, Chino T, Horst OV, Hacker BM, Clark EA, Dale BA, Chung WO.

BMC Immunol. 2010 Jul 9;11:37. doi: 10.1186/1471-2172-11-37.

11.

Defensin DEFB103 bidirectionally regulates chemokine and cytokine responses to a pro-inflammatory stimulus.

Harvey LE, Kohlgraf KG, Mehalick LA, Raina M, Recker EN, Radhakrishnan S, Prasad SA, Vidva R, Progulske-Fox A, Cavanaugh JE, Vali S, Brogden KA.

Sci Rep. 2013;3:1232. doi: 10.1038/srep01232. Epub 2013 Feb 6.

12.
13.

Green tea extract and its major constituent, epigallocatechin-3-gallate, induce epithelial beta-defensin secretion and prevent beta-defensin degradation by Porphyromonas gingivalis.

Lombardo Bedran TB, Feghali K, Zhao L, Palomari Spolidorio DM, Grenier D.

J Periodontal Res. 2014 Oct;49(5):615-23. doi: 10.1111/jre.12142. Epub 2013 Nov 9.

PMID:
24206194
14.

Gingipains produced by Porphyromonas gingivalis ATCC49417 degrade human-β-defensin 3 and affect peptide's antibacterial activity in vitro.

Maisetta G, Brancatisano FL, Esin S, Campa M, Batoni G.

Peptides. 2011 May;32(5):1073-7. doi: 10.1016/j.peptides.2011.02.003. Epub 2011 Feb 16.

PMID:
21335044
16.

Vitamin D reduces the inflammatory response by Porphyromonas gingivalis infection by modulating human β-defensin-3 in human gingival epithelium and periodontal ligament cells.

De Filippis A, Fiorentino M, Guida L, Annunziata M, Nastri L, Rizzo A.

Int Immunopharmacol. 2017 Jun;47:106-117. doi: 10.1016/j.intimp.2017.03.021. Epub 2017 Apr 3.

PMID:
28384529
17.

Mechanisms by which Porphyromonas gingivalis evades innate immunity.

Abdi K, Chen T, Klein BA, Tai AK, Coursen J, Liu X, Skinner J, Periasamy S, Choi Y, Kessler BM, Palmer RJ, Gittis A, Matzinger P, Duncan MJ, Singh NJ.

PLoS One. 2017 Aug 3;12(8):e0182164. doi: 10.1371/journal.pone.0182164. eCollection 2017.

18.

Human β-defensin 3 suppresses Porphyromonas gingivalis lipopolysaccharide-induced inflammation in RAW 264.7 cells and aortas of ApoE-deficient mice.

Bian T, Li L, Lyu J, Cui D, Lei L, Yan F.

Peptides. 2016 Aug;82:92-100. doi: 10.1016/j.peptides.2016.06.002. Epub 2016 Jun 11.

PMID:
27298203
20.

Histatin 5 binds to Porphyromonas gingivalis hemagglutinin B (HagB) and alters HagB-induced chemokine responses.

Borgwardt DS, Martin AD, Van Hemert JR, Yang J, Fischer CL, Recker EN, Nair PR, Vidva R, Chandrashekaraiah S, Progulske-Fox A, Drake D, Cavanaugh JE, Vali S, Zhang Y, Brogden KA.

Sci Rep. 2014 Jan 29;4:3904. doi: 10.1038/srep03904.

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