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Items: 1 to 20 of 153

1.

Structural properties of plant and mammalian lipoxygenases. Temperature-dependent conformational alterations and membrane binding ability.

Mei G, Di Venere A, Nicolai E, Angelucci CB, Ivanov I, Sabatucci A, Dainese E, Kuhn H, Maccarrone M.

Biochemistry. 2008 Sep 2;47(35):9234-42. doi: 10.1021/bi800638v. Epub 2008 Aug 12.

PMID:
18693758
3.

Structural biology of mammalian lipoxygenases: enzymatic consequences of targeted alterations of the protein structure.

Kuhn H, Saam J, Eibach S, Holzhütter HG, Ivanov I, Walther M.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):93-101. Epub 2005 Sep 9. Review.

PMID:
16168952
4.

Structural stability of soybean lipoxygenase-1 in solution as probed by small angle X-ray scattering.

Dainese E, Sabatucci A, van Zadelhoff G, Angelucci CB, Vachette P, Veldink GA, Agrò AF, Maccarrone M.

J Mol Biol. 2005 May 27;349(1):143-52. Epub 2005 Apr 2.

PMID:
15876374
5.

Effect of crystal freezing and small-molecule binding on internal cavity size in a large protein: X-ray and docking studies of lipoxygenase at ambient and low temperature at 2.0 A resolution.

Skrzypczak-Jankun E, Borbulevych OY, Zavodszky MI, Baranski MR, Padmanabhan K, Petricek V, Jankun J.

Acta Crystallogr D Biol Crystallogr. 2006 Jul;62(Pt 7):766-75. Epub 2006 Jun 20.

PMID:
16790932
6.

Probing conformational changes in lipoxygenases upon membrane binding: fine-tuning by the active site inhibitor ETYA.

Di Venere A, Nicolai E, Ivanov I, Dainese E, Adel S, Angelucci BC, Kuhn H, Maccarrone M, Mei G.

Biochim Biophys Acta. 2014 Jan;1841(1):1-10. doi: 10.1016/j.bbalip.2013.08.015. Epub 2013 Sep 3.

PMID:
24012824
7.

Tryptic digestion of soybean lipoxygenase-1 generates a 60 kDa fragment with improved activity and membrane binding ability.

Maccarrone M, Salucci ML, van Zadelhoff G, Malatesta F, Veldink G, Vliegenthart JF, Finazzi-Agrò A.

Biochemistry. 2001 Jun 12;40(23):6819-27.

PMID:
11389595
8.

The N-terminal β-barrel domain of mammalian lipoxygenases including mouse 5-lipoxygenase is not essential for catalytic activity and membrane binding but exhibits regulatory functions.

Walther M, Hofheinz K, Vogel R, Roffeis J, Kühn H.

Arch Biochem Biophys. 2011 Dec 1;516(1):1-9. doi: 10.1016/j.abb.2011.09.004. Epub 2011 Sep 17.

PMID:
21951814
9.

Probing dimerization and structural flexibility of mammalian lipoxygenases by small-angle X-ray scattering.

Shang W, Ivanov I, Svergun DI, Borbulevych OY, Aleem AM, Stehling S, Jankun J, Kühn H, Skrzypczak-Jankun E.

J Mol Biol. 2011 Jun 17;409(4):654-68. doi: 10.1016/j.jmb.2011.04.035. Epub 2011 Apr 20.

PMID:
21530540
10.

Molecular dynamics simulation of mammalian 15S-lipoxygenase with AMBER force field.

Moin ST, Hofer TS, Sattar R, Ul-Haq Z.

Eur Biophys J. 2011 Jun;40(6):715-26. doi: 10.1007/s00249-011-0684-5. Epub 2011 Mar 1.

PMID:
21360129
11.

Uncovering a calcium-regulated membrane-binding mechanism for soybean lipoxygenase-1.

Tatulian SA, Steczko J, Minor W.

Biochemistry. 1998 Nov 3;37(44):15481-90.

PMID:
9799511
12.
13.
14.

Enantioselective substrate specificity of 15-lipoxygenase 1.

Ivanov I, Romanov S, Ozdoba C, Holzhütter HG, Myagkova G, Kuhn H.

Biochemistry. 2004 Dec 21;43(50):15720-8.

PMID:
15595827
15.

Three-dimensional structure of a purple lipoxygenase.

Skrzypczak-Jankun E, Bross RA, Carroll RT, Dunham WR, Funk MO Jr.

J Am Chem Soc. 2001 Nov 7;123(44):10814-20.

PMID:
11686682
16.

Phenylalanine 353 is a primary determinant for the positional specificity of mammalian 15-lipoxygenases.

Borngräber S, Kuban RJ, Anton M, Kühn H.

J Mol Biol. 1996 Dec 20;264(5):1145-53.

PMID:
9000636
17.

Biologic relevance of lipoxygenase isoforms in atherogenesis.

Kuhn H.

Expert Rev Cardiovasc Ther. 2005 Nov;3(6):1099-110. Review.

PMID:
16293000
18.

Electrospray ionization mass spectrometry of soybean lipoxygenases: N-terminal acetylation, chemical modification, and solution conformation.

Peariso AM, Nicholson KM, Benjamin Jones R, Green-Church KB, Funk MO Jr.

Proteins. 2008 Feb 15;70(3):650-8.

PMID:
17879349
19.

Structure of soybean lipoxygenase L3 and a comparison with its L1 isoenzyme.

Skrzypczak-Jankun E, Amzel LM, Kroa BA, Funk MO Jr.

Proteins. 1997 Sep;29(1):15-31.

PMID:
9294864
20.

Structure and mechanism of lipoxygenases.

Prigge ST, Boyington JC, Faig M, Doctor KS, Gaffney BJ, Amzel LM.

Biochimie. 1997 Nov;79(11):629-36. Review.

PMID:
9479444

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