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Dissection of genetic mechanisms governing the expression of serum retroviral gp70 implicated in murine lupus nephritis.

Baudino L, Yoshinobu K, Morito N, Kikuchi S, Fossati-Jimack L, Morley BJ, Vyse TJ, Hirose S, Jørgensen TN, Tucker RM, Roark CL, Kotzin BL, Evans LH, Izui S.

J Immunol. 2008 Aug 15;181(4):2846-54.


TLR-mediated up-regulation of serum retroviral gp70 is controlled by the Sgp loci of lupus-prone mice.

Baudino L, Yoshinobu K, Dunand-Sauthier I, Evans LH, Izui S.

J Autoimmun. 2010 Sep;35(2):153-9. doi: 10.1016/j.jaut.2010.06.001. Epub 2010 Jul 8.


Sgp3 and Sgp4 control expression of distinct and restricted sets of xenotropic retroviruses encoding serum gp70 implicated in murine lupus nephritis.

Kihara M, Leroy V, Baudino L, Evans LH, Izui S.

J Autoimmun. 2011 Dec;37(4):311-8. doi: 10.1016/j.jaut.2011.09.001. Epub 2011 Oct 7.


Three Sgp loci act independently as well as synergistically to elevate the expression of specific endogenous retroviruses implicated in murine lupus.

Ito K, Baudino L, Kihara M, Leroy V, Vyse TJ, Evans LH, Izui S.

J Autoimmun. 2013 Jun;43:10-7. doi: 10.1016/j.jaut.2013.01.014. Epub 2013 Mar 7.


Sgp3 and TLR7 stimulation differentially alter the expression profile of modified polytropic retroviruses implicated in murine systemic lupus.

Leroy V, Kihara M, Baudino L, Brighouse G, Evans LH, Izui S.

J Autoimmun. 2012 Jun;38(4):361-8. doi: 10.1016/j.jaut.2012.03.002. Epub 2012 Apr 13.


Genetic control of glycoprotein 70 autoantigen production and its influence on immune complex levels and nephritis in murine lupus.

Tucker RM, Vyse TJ, Rozzo S, Roark CL, Izui S, Kotzin BL.

J Immunol. 2000 Aug 1;165(3):1665-72.


The Sgp3 locus derived from the 129 strain is responsible for enhanced endogenous retroviral expression in macroH2A1-deficient mice.

Baudino L, Changolkar LN, Pehrson JR, Izui S.

J Autoimmun. 2010 Dec;35(4):398-403. doi: 10.1016/j.jaut.2010.08.003. Epub 2010 Sep 15.


The Sgp3 locus on mouse chromosome 13 regulates nephritogenic gp70 autoantigen expression and predisposes to autoimmunity.

Laporte C, Ballester B, Mary C, Izui S, Reininger L.

J Immunol. 2003 Oct 1;171(7):3872-7.


Selective up-regulation of intact, but not defective env RNAs of endogenous modified polytropic retrovirus by the Sgp3 locus of lupus-prone mice.

Yoshinobu K, Baudino L, Santiago-Raber ML, Morito N, Dunand-Sauthier I, Morley BJ, Evans LH, Izui S.

J Immunol. 2009 Jun 15;182(12):8094-103. doi: 10.4049/jimmunol.0900263.


Differential role of three major New Zealand Black-derived loci linked with Yaa-induced murine lupus nephritis.

Kikuchi S, Fossati-Jimack L, Moll T, Amano H, Amano E, Ida A, Ibnou-Zekri N, Laporte C, Santiago-Raber ML, Rozzo SJ, Kotzin BL, Izui S.

J Immunol. 2005 Jan 15;174(2):1111-7.


Induction of high serum levels of retroviral env gene products (gp70) in mice by bacterial lipopolysaccharide.

Hara I, Izui S, McConahey PJ, Elder JH, Jensen FC, Dixon FJ.

Proc Natl Acad Sci U S A. 1981 Jul;78(7):4397-401.


A novel locus regulates both retroviral glycoprotein 70 and anti-glycoprotein 70 antibody production in New Zealand mice when crossed with BALB/c.

Rigby RJ, Rozzo SJ, Gill H, Fernandez-Hart T, Morley BJ, Izui S, Kotzin BL, Vyse TJ.

J Immunol. 2004 Apr 15;172(8):5078-85.


Pleomorphism among murine tissue-associated gp70s.

Butler GH, Del Villano BC.

J Gen Virol. 1984 Jan;65 ( Pt 1):141-51.


Expression and structure of serum gp70 as an acute phase protein in NZB mice.

Shigemoto K, Kubo S, Itoh Y, Tate G, Handa S, Maruyama N.

Mol Immunol. 1992 May;29(5):573-82.


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