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Items: 1 to 20 of 52

1.

The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis.

Xu W, Hellerbrand C, Köhler UA, Bugnon P, Kan YW, Werner S, Beyer TA.

Lab Invest. 2008 Oct;88(10):1068-78. doi: 10.1038/labinvest.2008.75. Epub 2008 Aug 4.

2.

Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development.

Marhenke S, Lamlé J, Buitrago-Molina LE, Cañón JM, Geffers R, Finegold M, Sporn M, Yamamoto M, Manns MP, Grompe M, Vogel A.

Hepatology. 2008 Aug;48(2):487-96. doi: 10.1002/hep.22391.

PMID:
18666252
3.

Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injury.

Lamlé J, Marhenke S, Borlak J, von Wasielewski R, Eriksson CJ, Geffers R, Manns MP, Yamamoto M, Vogel A.

Gastroenterology. 2008 Apr;134(4):1159-68. doi: 10.1053/j.gastro.2008.01.011. Epub 2008 Jan 11.

PMID:
18395094
4.

Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance.

Beyer TA, Xu W, Teupser D, auf dem Keller U, Bugnon P, Hildt E, Thiery J, Kan YW, Werner S.

EMBO J. 2008 Jan 9;27(1):212-23. Epub 2007 Dec 6.

5.

Transcription factor Nrf2 plays a pivotal role in protection against traumatic brain injury-induced acute intestinal mucosal injury in mice.

Jin W, Wang HD, Hu ZG, Yan W, Chen G, Yin HX.

J Surg Res. 2009 Dec;157(2):251-60. doi: 10.1016/j.jss.2008.08.003. Epub 2008 Sep 4.

PMID:
19394962
6.

Influence of Nrf2 genotype on pulmonary NF-kappaB activity and inflammatory response after traumatic brain injury.

Jin W, Zhu L, Guan Q, Chen G, Wang QF, Yin HX, Hang CH, Shi JX, Wang HD.

Ann Clin Lab Sci. 2008 Summer;38(3):221-7.

PMID:
18715849
7.

Inhibition of liver fibrosis by solubilized coenzyme Q10: Role of Nrf2 activation in inhibiting transforming growth factor-beta1 expression.

Choi HK, Pokharel YR, Lim SC, Han HK, Ryu CS, Kim SK, Kwak MK, Kang KW.

Toxicol Appl Pharmacol. 2009 Nov 1;240(3):377-84. doi: 10.1016/j.taap.2009.07.030. Epub 2009 Aug 6.

PMID:
19647758
8.

Hepatic fibrosis is enhanced and accompanied by robust oval cell activation after chronic carbon tetrachloride administration to Egr-1-deficient mice.

Pritchard MT, Nagy LE.

Am J Pathol. 2010 Jun;176(6):2743-52. doi: 10.2353/ajpath.2010.091186. Epub 2010 Apr 15.

9.

Increased intestinal inflammatory response and gut barrier dysfunction in Nrf2-deficient mice after traumatic brain injury.

Jin W, Wang H, Ji Y, Hu Q, Yan W, Chen G, Yin H.

Cytokine. 2008 Oct;44(1):135-40. doi: 10.1016/j.cyto.2008.07.005. Epub 2008 Aug 21.

PMID:
18722136
10.

Enhanced spontaneous and benzo(a)pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice.

Aoki Y, Hashimoto AH, Amanuma K, Matsumoto M, Hiyoshi K, Takano H, Masumura K, Itoh K, Nohmi T, Yamamoto M.

Cancer Res. 2007 Jun 15;67(12):5643-8.

11.

Dysfunction of Nrf2 decreases KBrO3-induced oxidative DNA damage in Ogg1-null mice.

Jałoszyński P, Murata S, Shinkai Y, Takahashi S, Kumagai Y, Nishimura S, Yamamoto M.

Biochem Biophys Res Commun. 2007 Dec 28;364(4):966-71. Epub 2007 Oct 29.

PMID:
17971305
12.

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile duct ligation in mice.

Giebeler A, Boekschoten MV, Klein C, Borowiak M, Birchmeier C, Gassler N, Wasmuth HE, Müller M, Trautwein C, Streetz KL.

Gastroenterology. 2009 Jul;137(1):297-308, 308.e1-4. doi: 10.1053/j.gastro.2009.01.068. Epub 2009 Feb 5.

PMID:
19208365
13.
14.

Nrf2 and antioxidant defense against CYP2E1 toxicity.

Cederbaum A.

Expert Opin Drug Metab Toxicol. 2009 Oct;5(10):1223-44. doi: 10.1517/17425250903143769. Review.

PMID:
19671018
15.

Antifibrotic effect through the regulation of transcription factor using ring type-Sp1 decoy oligodeoxynucleotide in carbon tetrachloride-induced liver fibrosis.

Park JH, Jo JH, Kim KH, Kim SJ, Lee WR, Park KK, Park JB.

J Gene Med. 2009 Sep;11(9):824-33. doi: 10.1002/jgm.1355.

PMID:
19554625
16.

Zizyphus spina-christi protects against carbon tetrachloride-induced liver fibrosis in rats.

Amin A, Mahmoud-Ghoneim D.

Food Chem Toxicol. 2009 Aug;47(8):2111-9. doi: 10.1016/j.fct.2009.05.038. Epub 2009 Jun 13.

PMID:
19500642
17.

Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice.

Yoh K, Hirayama A, Ishizaki K, Yamada A, Takeuchi M, Yamagishi S, Morito N, Nakano T, Ojima M, Shimohata H, Itoh K, Takahashi S, Yamamoto M.

Genes Cells. 2008 Nov;13(11):1159-70. doi: 10.1111/j.1365-2443.2008.01234.x.

18.

Activated Nrf2 impairs liver regeneration in mice by activation of genes involved in cell-cycle control and apoptosis.

Köhler UA, Kurinna S, Schwitter D, Marti A, Schäfer M, Hellerbrand C, Speicher T, Werner S.

Hepatology. 2014 Aug;60(2):670-8. doi: 10.1002/hep.26964. Epub 2014 Jun 18.

PMID:
24310875
19.

A gain-of-function mutation in the PDGFR-beta alters the kinetics of injury response in liver and skin.

Krampert M, Heldin CH, Heuchel RL.

Lab Invest. 2008 Nov;88(11):1204-14. doi: 10.1038/labinvest.2008.81. Epub 2008 Sep 1.

20.

Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy.

Ni HM, Woolbright BL, Williams J, Copple B, Cui W, Luyendyk JP, Jaeschke H, Ding WX.

J Hepatol. 2014 Sep;61(3):617-25. doi: 10.1016/j.jhep.2014.04.043. Epub 2014 May 9.

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