Similar articles for PMID: 18678614

Year	Number of Results
1996	1
2007	2
2008	7
2009	10
2010	12
2011	11
2012	10
2013	10
2014	12
2015	11
2016	7
2017	5
2018	10
2019	6
2020	1
2021	3
2022	4
2023	3
2024	0

1

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations.

Orho-Melander M, Melander O, Guiducci C, Perez-Martinez P, Corella D, Roos C, Tewhey R, Rieder MJ, Hall J, Abecasis G, Tai ES, Welch C, Arnett DK, Lyssenko V, Lindholm E, Saxena R, de Bakker PI, Burtt N, Voight BF, Hirschhorn JN, Tucker KL, Hedner T, Tuomi T, Isomaa B, Eriksson KF, Taskinen MR, Wahlstrand B, Hughes TE, Parnell LD, Lai CQ, Berglund G, Peltonen L, Vartiainen E, Jousilahti P, Havulinna AS, Salomaa V, Nilsson P, Groop L, Altshuler D, Ordovas JM, Kathiresan S. Orho-Melander M, et al. Diabetes. 2008 Nov;57(11):3112-21. doi: 10.2337/db08-0516. Epub 2008 Aug 4. Diabetes. 2008. PMID: 18678614 Free PMC article.

2

The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population.

Vaxillaire M, Cavalcanti-Proença C, Dechaume A, Tichet J, Marre M, Balkau B, Froguel P; DESIR Study Group. Vaxillaire M, et al. Diabetes. 2008 Aug;57(8):2253-7. doi: 10.2337/db07-1807. Epub 2008 Jun 12. Diabetes. 2008. PMID: 18556336 Free PMC article.

3

Interaction effect of genetic polymorphisms in glucokinase (GCK) and glucokinase regulatory protein (GCKR) on metabolic traits in healthy Chinese adults and adolescents.

Tam CH, Ma RC, So WY, Wang Y, Lam VK, Germer S, Martin M, Chan JC, Ng MC. Tam CH, et al. Diabetes. 2009 Mar;58(3):765-9. doi: 10.2337/db08-1277. Epub 2008 Dec 10. Diabetes. 2009. PMID: 19073768 Free PMC article.

4

Triglyceride response to an intensive lifestyle intervention is enhanced in carriers of the GCKR Pro446Leu polymorphism.

Pollin TI, Jablonski KA, McAteer JB, Saxena R, Kathiresan S, Kahn SE, Goldberg RB, Altshuler D, Florez JC; Diabetes Prevention Program Research Group. Pollin TI, et al. J Clin Endocrinol Metab. 2011 Jul;96(7):E1142-7. doi: 10.1210/jc.2010-2324. Epub 2011 Apr 27. J Clin Endocrinol Metab. 2011. PMID: 21525158 Free PMC article. Clinical Trial.

5

Genotype effects of glucokinase regulator on lipid profiles and glycemic status are modified by circulating calcium levels: results from the Korean Genome and Epidemiology Study.

Kim OY, Kwak SY, Lim H, Shin MJ. Kim OY, et al. Nutr Res. 2018 Dec;60:96-105. doi: 10.1016/j.nutres.2018.09.008. Epub 2018 Sep 29. Nutr Res. 2018. PMID: 30527264

6

Lifestyle Intervention for Weight Loss and Cardiometabolic Changes in the Setting of Glucokinase Regulatory Protein Inhibition: Glucokinase Regulatory Protein-Leu446Pro Variant in Look AHEAD.

Belalcazar LM, Papandonatos GD, Erar B, Peter I, Alkofide H, Balasubramanyam A, Brautbar A, Kahn SE, Knowler WC, Ballantyne CM, McCaffery JM, Huggins GS; Genetics Subgroup of the Look AHEAD Study*. Belalcazar LM, et al. Circ Cardiovasc Genet. 2016 Feb;9(1):71-8. doi: 10.1161/CIRCGENETICS.115.001192. Epub 2015 Nov 17. Circ Cardiovasc Genet. 2016. PMID: 26578543 Free PMC article. Clinical Trial.

7

Early gene-diet interaction between glucokinase regulatory protein (GCKR) polymorphism, vegetable and fish intakes in modulating triglyceride levels in healthy adolescents.

Tam CH, Wang Y, Lee HM, Luk AO, Tong PC, Chan MH, Ozaki R, Kong AP, So WY, Chan JC, Ma RC. Tam CH, et al. Nutr Metab Cardiovasc Dis. 2015 Oct;25(10):951-8. doi: 10.1016/j.numecd.2015.06.011. Epub 2015 Jul 7. Nutr Metab Cardiovasc Dis. 2015. PMID: 26234566

8

Associations of common polymorphisms in GCKR with type 2 diabetes and related traits in a Han Chinese population: a case-control study.

Ling Y, Li X, Gu Q, Chen H, Lu D, Gao X. Ling Y, et al. BMC Med Genet. 2011 May 13;12:66. doi: 10.1186/1471-2350-12-66. BMC Med Genet. 2011. PMID: 21569451 Free PMC article.

9

Functional glucokinase regulator gene variants have inverse effects on triglyceride and glucose levels, and decrease the risk of obesity in children.

Horvatovich K, Bokor S, Polgar N, Kisfali P, Hadarits F, Jaromi L, Csongei V, Repasy J, Molnar D, Melegh B. Horvatovich K, et al. Diabetes Metab. 2011 Nov;37(5):432-9. doi: 10.1016/j.diabet.2011.02.003. Epub 2011 Apr 20. Diabetes Metab. 2011. PMID: 21511510

10

Pleiotropic Effects of Common and Rare GCKR Exonic Mutations on Cardiometabolic Traits.

Yeh KH, Hsu LA, Teng MS, Wu S, Chou HH, Ko YL. Yeh KH, et al. Genes (Basel). 2022 Mar 10;13(3):491. doi: 10.3390/genes13030491. Genes (Basel). 2022. PMID: 35328045 Free PMC article.

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