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Items: 1 to 20 of 299

1.

Prevention of muscle fibrosis and improvement in muscle performance in the mdx mouse by halofuginone.

Turgeman T, Hagai Y, Huebner K, Jassal DS, Anderson JE, Genin O, Nagler A, Halevy O, Pines M.

Neuromuscul Disord. 2008 Nov;18(11):857-68. doi: 10.1016/j.nmd.2008.06.386. Epub 2008 Jul 30.

PMID:
18672370
2.

Halofuginone inhibits Smad3 phosphorylation via the PI3K/Akt and MAPK/ERK pathways in muscle cells: effect on myotube fusion.

Roffe S, Hagai Y, Pines M, Halevy O.

Exp Cell Res. 2010 Apr 1;316(6):1061-9. doi: 10.1016/j.yexcr.2010.01.003. Epub 2010 Jan 11.

PMID:
20060825
3.

Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention.

Zion O, Genin O, Kawada N, Yoshizato K, Roffe S, Nagler A, Iovanna JL, Halevy O, Pines M.

Pancreas. 2009 May;38(4):427-35. doi: 10.1097/MPA.0b013e3181967670.

PMID:
19188864
4.

Functional resolution of fibrosis in mdx mouse dystrophic heart and skeletal muscle by halofuginone.

Huebner KD, Jassal DS, Halevy O, Pines M, Anderson JE.

Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1550-61. doi: 10.1152/ajpheart.01253.2007. Epub 2008 Feb 8.

5.

Fibrosis inhibition and muscle histopathology improvement in laminin-alpha2-deficient mice.

Nevo Y, Halevy O, Genin O, Moshe I, Turgeman T, Harel M, Biton E, Reif S, Pines M.

Muscle Nerve. 2010 Aug;42(2):218-29. doi: 10.1002/mus.21706.

PMID:
20589893
6.

Focusing on fibrosis: halofuginone-induced functional improvement in the mdx mouse model of Duchenne muscular dystrophy.

McLoon LK.

Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1505-7. doi: 10.1152/ajpheart.00176.2008. Epub 2008 Feb 29. No abstract available.

7.

Halofuginone improves muscle-cell survival in muscular dystrophies.

Bodanovsky A, Guttman N, Barzilai-Tutsch H, Genin O, Levy O, Pines M, Halevy O.

Biochim Biophys Acta. 2014 Jul;1843(7):1339-47. doi: 10.1016/j.bbamcr.2014.03.025. Epub 2014 Apr 2.

8.

Halofuginone and muscular dystrophy.

Pines M, Halevy O.

Histol Histopathol. 2011 Jan;26(1):135-46. doi: 10.14670/HH-26.135. Review.

PMID:
21117034
9.

Implication of the satellite cell in dystrophic muscle fibrosis: a self-perpetuating mechanism of collagen overproduction.

Alexakis C, Partridge T, Bou-Gharios G.

Am J Physiol Cell Physiol. 2007 Aug;293(2):C661-9. Epub 2007 May 2.

10.

Inhibition of muscle fibrosis and improvement of muscle histopathology in dysferlin knock-out mice treated with halofuginone.

Halevy O, Genin O, Barzilai-Tutsch H, Pima Y, Levi O, Moshe I, Pines M.

Histol Histopathol. 2013 Feb;28(2):211-26. doi: 10.14670/HH-28.211.

PMID:
23275304
11.

Pentoxifylline fails to attenuate fibrosis in dystrophic (mdx) diaphragm muscle.

Gosselin LE, Williams JE.

Muscle Nerve. 2006 Jun;33(6):820-3.

PMID:
16502423
12.

The involvement of collagen triple helix repeat containing 1 in muscular dystrophies.

Spector I, Zilberstein Y, Lavy A, Genin O, Barzilai-Tutsch H, Bodanovsky A, Halevy O, Pines M.

Am J Pathol. 2013 Mar;182(3):905-16. doi: 10.1016/j.ajpath.2012.11.004. Epub 2012 Dec 27.

PMID:
23274062
13.

Leukemia inhibitory factor ameliorates muscle fiber degeneration in the mdx mouse.

Austin L, Bower JJ, Bennett TM, Lynch GS, Kapsa R, White JD, Barnard W, Gregorevic P, Byrne E.

Muscle Nerve. 2000 Nov;23(11):1700-5.

PMID:
11054748
14.

Stimulation of calcineurin Aalpha activity attenuates muscle pathophysiology in mdx dystrophic mice.

Stupka N, Schertzer JD, Bassel-Duby R, Olson EN, Lynch GS.

Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R983-92. doi: 10.1152/ajpregu.00375.2007. Epub 2008 Jan 16.

15.

Regenerative capacity of the dystrophic (mdx) diaphragm after induced injury.

Matecki S, Guibinga GH, Petrof BJ.

Am J Physiol Regul Integr Comp Physiol. 2004 Oct;287(4):R961-8. Epub 2004 Jun 10.

16.

Phenotype of dystrophinopathy in old mdx mice.

Lefaucheur JP, Pastoret C, Sebille A.

Anat Rec. 1995 May;242(1):70-6.

PMID:
7604983
17.

The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy.

Stedman HH, Sweeney HL, Shrager JB, Maguire HC, Panettieri RA, Petrof B, Narusawa M, Leferovich JM, Sladky JT, Kelly AM.

Nature. 1991 Aug 8;352(6335):536-9.

PMID:
1865908
18.
19.

Site-dependent pathological differences in smooth muscles and skeletal muscles of the adult mdx mouse.

Boland B, Himpens B, Denef JF, Gillis JM.

Muscle Nerve. 1995 Jun;18(6):649-57.

PMID:
7753128
20.

Morphometric analysis of mdx diaphragm muscle fibres. Comparison with hindlimb muscles.

Louboutin JP, Fichter-Gagnepain V, Thaon E, Fardeau M.

Neuromuscul Disord. 1993 Sep-Nov;3(5-6):463-9.

PMID:
8186695

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