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Items: 1 to 20 of 148

1.

Molecular architecture of native HIV-1 gp120 trimers.

Liu J, Bartesaghi A, Borgnia MJ, Sapiro G, Subramaniam S.

Nature. 2008 Sep 4;455(7209):109-13. doi: 10.1038/nature07159. Epub 2008 Jul 30.

2.

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures.

Harris A, Borgnia MJ, Shi D, Bartesaghi A, He H, Pejchal R, Kang YK, Depetris R, Marozsan AJ, Sanders RW, Klasse PJ, Milne JL, Wilson IA, Olson WC, Moore JP, Subramaniam S.

Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11440-5. doi: 10.1073/pnas.1101414108. Epub 2011 Jun 27.

3.

Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography.

White TA, Bartesaghi A, Borgnia MJ, de la Cruz MJ, Nandwani R, Hoxie JA, Bess JW, Lifson JD, Milne JL, Subramaniam S.

J Virol. 2011 Dec;85(23):12114-23. doi: 10.1128/JVI.05297-11. Epub 2011 Sep 21.

5.

Structural mechanism of trimeric HIV-1 envelope glycoprotein activation.

Tran EE, Borgnia MJ, Kuybeda O, Schauder DM, Bartesaghi A, Frank GA, Sapiro G, Milne JL, Subramaniam S.

PLoS Pathog. 2012;8(7):e1002797. doi: 10.1371/journal.ppat.1002797. Epub 2012 Jul 12.

6.

Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure.

White TA, Bartesaghi A, Borgnia MJ, Meyerson JR, de la Cruz MJ, Bess JW, Nandwani R, Hoxie JA, Lifson JD, Milne JL, Subramaniam S.

PLoS Pathog. 2010 Dec 23;6(12):e1001249. doi: 10.1371/journal.ppat.1001249.

7.

Effects of the I559P gp41 change on the conformation and function of the human immunodeficiency virus (HIV-1) membrane envelope glycoprotein trimer.

Alsahafi N, Debbeche O, Sodroski J, Finzi A.

PLoS One. 2015 Apr 7;10(4):e0122111. doi: 10.1371/journal.pone.0122111. eCollection 2015. Erratum in: PLoS One. 2015;10(5):e0129405.

8.

Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 binding.

Finzi A, Pacheco B, Xiang SH, Pancera M, Herschhorn A, Wang L, Zeng X, Desormeaux A, Kwong PD, Sodroski J.

J Virol. 2012 Sep;86(17):8974-86. doi: 10.1128/JVI.01076-12. Epub 2012 Jun 13.

9.

Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer.

Mao Y, Wang L, Gu C, Herschhorn A, Xiang SH, Haim H, Yang X, Sodroski J.

Nat Struct Mol Biol. 2012 Sep;19(9):893-9. doi: 10.1038/nsmb.2351. Epub 2012 Aug 5.

11.

Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds.

Madani N, Princiotto AM, Zhao C, Jahanbakhshsefidi F, Mertens M, Herschhorn A, Melillo B, Smith AB 3rd, Sodroski J.

J Virol. 2017 Jan 18;91(3). pii: e01880-16. doi: 10.1128/JVI.01880-16. Print 2017 Feb 1.

12.

Restraining the conformation of HIV-1 gp120 by removing a flexible loop.

Rits-Volloch S, Frey G, Harrison SC, Chen B.

EMBO J. 2006 Oct 18;25(20):5026-35. Epub 2006 Sep 28.

13.

The antigenic structure of the HIV gp120 envelope glycoprotein.

Wyatt R, Kwong PD, Desjardins E, Sweet RW, Robinson J, Hendrickson WA, Sodroski JG.

Nature. 1998 Jun 18;393(6686):705-11.

PMID:
9641684
14.

Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimer.

Mao Y, Wang L, Gu C, Herschhorn A, Désormeaux A, Finzi A, Xiang SH, Sodroski JG.

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12438-43. doi: 10.1073/pnas.1307382110. Epub 2013 Jun 11.

15.

Biochemically defined HIV-1 envelope glycoprotein variant immunogens display differential binding and neutralizing specificities to the CD4-binding site.

Feng Y, McKee K, Tran K, O'Dell S, Schmidt SD, Phogat A, Forsell MN, Karlsson Hedestam GB, Mascola JR, Wyatt RT.

J Biol Chem. 2012 Feb 17;287(8):5673-86. doi: 10.1074/jbc.M111.317776. Epub 2011 Dec 13.

16.

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops.

Kwon YD, Finzi A, Wu X, Dogo-Isonagie C, Lee LK, Moore LR, Schmidt SD, Stuckey J, Yang Y, Zhou T, Zhu J, Vicic DA, Debnath AK, Shapiro L, Bewley CA, Mascola JR, Sodroski JG, Kwong PD.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5663-8. doi: 10.1073/pnas.1112391109. Epub 2012 Mar 26.

17.

Structural definition of a conserved neutralization epitope on HIV-1 gp120.

Zhou T, Xu L, Dey B, Hessell AJ, Van Ryk D, Xiang SH, Yang X, Zhang MY, Zwick MB, Arthos J, Burton DR, Dimitrov DS, Sodroski J, Wyatt R, Nabel GJ, Kwong PD.

Nature. 2007 Feb 15;445(7129):732-7.

18.

Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers.

Khayat R, Lee JH, Julien JP, Cupo A, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB.

J Virol. 2013 Sep;87(17):9865-72. doi: 10.1128/JVI.01222-13. Epub 2013 Jul 3.

19.

Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors.

Pacheco B, Alsahafi N, Debbeche O, Prévost J, Ding S, Chapleau JP, Herschhorn A, Madani N, Princiotto A, Melillo B, Gu C, Zeng X, Mao Y, Smith AB 3rd, Sodroski J, Finzi A.

J Virol. 2017 Feb 14;91(5). pii: e02219-16. doi: 10.1128/JVI.02219-16. Print 2017 Mar 1.

20.

Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.

Ozorowski G, Pallesen J, de Val N, Lyumkis D, Cottrell CA, Torres JL, Copps J, Stanfield RL, Cupo A, Pugach P, Moore JP, Wilson IA, Ward AB.

Nature. 2017 Jul 20;547(7663):360-363. doi: 10.1038/nature23010. Epub 2017 Jul 12.

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