Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 125

1.

Jararhagin, a snake venom metalloprotease-disintegrin, activates the Rac1 GTPase and stimulates neurite outgrowth in neuroblastoma cells.

Costa EP, Del Debbio CB, Cintra LC, da Fontoura Costa L, Hamassaki DE, Santos MF.

Toxicon. 2008 Aug 1;52(2):380-4. doi: 10.1016/j.toxicon.2008.04.165. Epub 2008 May 29.

PMID:
18653205
2.

Pulmonary hemorrhage induced by jararhagin, a metalloproteinase from Bothrops jararaca snake venom.

Escalante T, Núñez J, Moura da Silva AM, Rucavado A, Theakston RD, Gutiérrez JM.

Toxicol Appl Pharmacol. 2003 Nov 15;193(1):17-28.

PMID:
14613713
4.

Jararhagin and its multiple effects on hemostasis.

Laing GD, Moura-da-Silva AM.

Toxicon. 2005 Jun 15;45(8):987-96. Epub 2005 Apr 2. Review.

PMID:
15922770
5.

Collagen binding is a key factor for the hemorrhagic activity of snake venom metalloproteinases.

Moura-da-Silva AM, Ramos OH, Baldo C, Niland S, Hansen U, Ventura JS, Furlan S, Butera D, Della-Casa MS, Tanjoni I, Clissa PB, Fernandes I, Chudzinski-Tavassi AM, Eble JA.

Biochimie. 2008 Mar;90(3):484-92. Epub 2007 Dec 4.

PMID:
18096518
6.

Jararhagin, a snake venom metalloproteinase, induces a specialized form of apoptosis (anoikis) selective to endothelial cells.

Tanjoni I, Weinlich R, Della-Casa MS, Clissa PB, Saldanha-Gama RF, de Freitas MS, Barja-Fidalgo C, Amarante-Mendes GP, Moura-da-Silva AM.

Apoptosis. 2005 Aug;10(4):851-61.

PMID:
16133875
7.

Jararhagin ECD-containing disintegrin domain: expression in escherichia coli and inhibition of the platelet-collagen interaction.

Moura-da-Silva AM, Línica A, Della-Casa MS, Kamiguti AS, Ho PL, Crampton JM, Theakston RD.

Arch Biochem Biophys. 1999 Sep 15;369(2):295-301.

PMID:
10486149
8.

The reprolysin jararhagin, a snake venom metalloproteinase, functions as a fibrillar collagen agonist involved in fibroblast cell adhesion and signaling.

Zigrino P, Kamiguti AS, Eble J, Drescher C, Nischt R, Fox JW, Mauch C.

J Biol Chem. 2002 Oct 25;277(43):40528-35. Epub 2002 Aug 16.

9.

Receptor for advanced glycation end products (RAGE) mediates neuronal differentiation and neurite outgrowth.

Wang L, Li S, Jungalwala FB.

J Neurosci Res. 2008 May 1;86(6):1254-66.

PMID:
18058943
10.

Crystallization and preliminary X-ray analysis of jararhagin, a metalloproteinase/disintegrin from Bothrops jararaca snake venom.

Souza DH, Selistre-de-Araujo HS, Moura-da-Silva AM, Della-Casa MS, Oliva G, Garratt RC.

Acta Crystallogr D Biol Crystallogr. 2001 Aug;57(Pt 8):1135-7. Epub 2001 Jul 23.

PMID:
11468397
11.

Enhancement of plasma fibrinolysis in vitro by jararhagin, the main haemorrhagic metalloproteinase in Bothrops jararaca venom.

Sugiki M, Maruyama M, Yoshida E, Mihara H, Kamiguti AS, Theakston DG.

Toxicon. 1995 Dec;33(12):1605-17.

PMID:
8866618
12.

Phosphorylation of RhoGDI1 by p21-activated kinase 2 mediates basic fibroblast growth factor-stimulated neurite outgrowth in PC12 cells.

Shin EY, Shim ES, Lee CS, Kim HK, Kim EG.

Biochem Biophys Res Commun. 2009 Feb 6;379(2):384-9. doi: 10.1016/j.bbrc.2008.12.066. Epub 2008 Dec 25.

PMID:
19103160
13.

Importance of jararhagin disintegrin-like and cysteine-rich domains in the early events of local inflammatory response.

Clissa PB, Lopes-Ferreira M, Della-Casa MS, Farsky SH, Moura-da-Silva AM.

Toxicon. 2006 Apr;47(5):591-6. Epub 2006 Mar 24.

PMID:
16564063
14.

Inhibition of melanoma cells tumorigenicity by the snake venom toxin jararhagin.

Corrêa MC Jr, Maria DA, Moura-da-Silva AM, Pizzocaro KF, Ruiz IR.

Toxicon. 2002 Jun;40(6):739-48.

PMID:
12175610
15.

The effect of post-translational modifications on the hemorrhagic activity of snake venom metalloproteinases.

García LT, Parreiras e Silva LT, Ramos OH, Carmona AK, Bersanetti PA, Selistre-de-Araujo HS.

Comp Biochem Physiol C Toxicol Pharmacol. 2004 May;138(1):23-32.

PMID:
15313443
16.

JNK phosphorylation of paxillin, acting through the Rac1 and Cdc42 signaling cascade, mediates neurite extension in N1E-115 cells.

Yamauchi J, Miyamoto Y, Sanbe A, Tanoue A.

Exp Cell Res. 2006 Sep 10;312(15):2954-61. Epub 2006 Jun 7.

PMID:
16814769
17.

Outgrowth of neurites from NIE-115 neuroblastoma cells is prevented on repulsive substrates through the action of PAK.

Marler KJ, Kozma R, Ahmed S, Dong JM, Hall C, Lim L.

Mol Cell Biol. 2005 Jun;25(12):5226-41.

18.

The snake venom metalloproteases berythractivase and jararhagin activate endothelial cells.

Schattner M, Fritzen M, Ventura Jde S, de Albuquerque Modesto JC, Pozner RG, Moura-da-Silva AM, Chudzinski-Tavassi AM.

Biol Chem. 2005 Apr;386(4):369-74.

PMID:
15899699
19.

Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells.

Hajdo-Milasinović A, Ellenbroek SI, van Es S, van der Vaart B, Collard JG.

J Cell Sci. 2007 Feb 15;120(Pt 4):555-66. Epub 2007 Jan 23.

20.

Evidence for heterogeneous forms of the snake venom metalloproteinase jararhagin: a factor contributing to snake venom variability.

Moura-da-Silva AM, Della-Casa MS, David AS, Assakura MT, Butera D, Lebrun I, Shannon JD, Serrano SM, Fox JW.

Arch Biochem Biophys. 2003 Jan 15;409(2):395-401.

PMID:
12504907

Supplemental Content

Support Center