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Items: 1 to 20 of 97

1.

Role of acetaldehyde in ethanol-induced elevation of the neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one in rats.

Boyd KN, O'Buckley TK, Morrow AL.

Alcohol Clin Exp Res. 2008 Oct;32(10):1774-81. doi: 10.1111/j.1530-0277.2008.00762.x. Epub 2008 Jul 24.

2.

Neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats.

Khisti RT, VanDoren MJ, O'Buckley T, Morrow AL.

Brain Res. 2003 Aug 8;980(2):255-65.

PMID:
12867266
3.

Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol.

VanDoren MJ, Matthews DB, Janis GC, Grobin AC, Devaud LL, Morrow AL.

J Neurosci. 2000 Mar 1;20(5):1982-9.

4.

Ethanol-induced elevation of 3 alpha-hydroxy-5 alpha-pregnan-20-one does not modulate motor incoordination in rats.

Khisti RT, VanDoren MJ, Matthews DB, Morrow AL.

Alcohol Clin Exp Res. 2004 Aug;28(8):1249-56.

PMID:
15318125
5.
6.

Chronic intermittent ethanol exposure and withdrawal alters (3α,5α)-3-hydroxy-pregnan-20-one immunostaining in cortical and limbic brain regions of C57BL/6J mice.

Maldonado-Devincci AM, Cook JB, O'Buckley TK, Morrow DH, McKinley RE, Lopez MF, Becker HC, Morrow AL.

Alcohol Clin Exp Res. 2014 Oct;38(10):2561-71. doi: 10.1111/acer.12530. Epub 2014 Oct 7.

7.

Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats.

Hirani K, Sharma AN, Jain NS, Ugale RR, Chopde CT.

Psychopharmacology (Berl). 2005 Jul;180(2):267-78. Epub 2005 Feb 18.

PMID:
15719223
8.

Ethanol administration produces divergent changes in GABAergic neuroactive steroid immunohistochemistry in the rat brain.

Cook JB, Dumitru AM, O'Buckley TK, Morrow AL.

Alcohol Clin Exp Res. 2014 Jan;38(1):90-9. doi: 10.1111/acer.12223. Epub 2013 Jul 26.

9.

Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans.

Porcu P, O'Buckley TK, Alward SE, Song SC, Grant KA, de Wit H, Leslie Morrow A.

Alcohol Clin Exp Res. 2010 Mar 1;34(3):432-42. doi: 10.1111/j.1530-0277.2009.01123.x. Epub 2009 Dec 17.

10.

Moderate doses of ethanol fail to increase plasma levels of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one-like immunoreactivity in healthy men and women.

Holdstock L, Penland SN, Morrow AL, de Wit H.

Psychopharmacology (Berl). 2006 Jun;186(3):442-50. Epub 2005 Oct 21.

PMID:
16240164
11.

Ethanol alters local cellular levels of (3α,5α)-3-hydroxypregnan-20-one (3α,5α-THP) independent of the adrenals in subcortical brain regions.

Cook JB, Nelli SM, Neighbors MR, Morrow DH, O'Buckley TK, Maldonado-Devincci AM, Morrow AL.

Neuropsychopharmacology. 2014 Jul;39(8):1978-87. doi: 10.1038/npp.2014.46. Epub 2014 Feb 25.

12.

Behavioral action of ethanol in Porsolt's forced swim test: modulation by 3 alpha-hydroxy-5 alpha-pregnan-20-one.

Hirani K, Khisti RT, Chopde CT.

Neuropharmacology. 2002 Dec;43(8):1339-50.

PMID:
12527484
13.
14.

Genetic differences in behavioral sensitivity to a neuroactive steroid.

Finn DA, Roberts AJ, Lotrich F, Gallaher EJ.

J Pharmacol Exp Ther. 1997 Feb;280(2):820-8.

17.

Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration.

Cook JB, Werner DF, Maldonado-Devincci AM, Leonard MN, Fisher KR, O'Buckley TK, Porcu P, McCown TJ, Besheer J, Hodge CW, Morrow AL.

J Neurosci. 2014 Apr 23;34(17):5824-34. doi: 10.1523/JNEUROSCI.4733-13.2014.

18.

Chronic ethanol exposure produces tolerance to elevations in neuroactive steroids: mechanisms and reversal by exogenous ACTH.

Boyd KN, Kumar S, O'Buckley TK, Morrow AL.

J Neurochem. 2010 Oct;115(1):142-52. doi: 10.1111/j.1471-4159.2010.06904.x. Epub 2010 Jul 30.

19.

Reduction of circulating and selective limbic brain levels of (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) following forced swim stress in C57BL/6J mice.

Maldonado-Devincci AM, Beattie MC, Morrow DH, McKinley RE, Cook JB, O'Buckley TK, Morrow AL.

Psychopharmacology (Berl). 2014 Sep;231(17):3281-92. doi: 10.1007/s00213-014-3552-z. Epub 2014 Apr 18.

20.

Social isolation-induced increase in the sensitivity of rats to the steroidogenic effect of ethanol.

Serra M, Pisu MG, Floris I, Cara V, Purdy RH, Biggio G.

J Neurochem. 2003 Apr;85(1):257-63.

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