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Items: 1 to 20 of 126

1.

Human cytomegalovirus regulates bioactive sphingolipids.

Machesky NJ, Zhang G, Raghavan B, Zimmerman P, Kelly SL, Merrill AH Jr, Waldman WJ, Van Brocklyn JR, Trgovcich J.

J Biol Chem. 2008 Sep 19;283(38):26148-60. doi: 10.1074/jbc.M710181200. Epub 2008 Jul 20.

2.

De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells.

Berdyshev EV, Gorshkova IA, Usatyuk P, Zhao Y, Saatian B, Hubbard W, Natarajan V.

Cell Signal. 2006 Oct;18(10):1779-92. Epub 2006 Mar 10.

PMID:
16529909
3.

FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells.

Berdyshev EV, Gorshkova I, Skobeleva A, Bittman R, Lu X, Dudek SM, Mirzapoiazova T, Garcia JG, Natarajan V.

J Biol Chem. 2009 Feb 27;284(9):5467-77. doi: 10.1074/jbc.M805186200. Epub 2009 Jan 1.

4.

Sphingosine kinase localization in the control of sphingolipid metabolism.

Siow DL, Anderson CD, Berdyshev EV, Skobeleva A, Natarajan V, Pitson SM, Wattenberg BW.

Adv Enzyme Regul. 2011;51(1):229-44. doi: 10.1016/j.advenzreg.2010.09.004. Epub 2010 Nov 12.

5.

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids.

Kono M, Dreier JL, Ellis JM, Allende ML, Kalkofen DN, Sanders KM, Bielawski J, Bielawska A, Hannun YA, Proia RL.

J Biol Chem. 2006 Mar 17;281(11):7324-31. Epub 2005 Dec 27.

6.

The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death.

Van Brocklyn JR, Williams JB.

Comp Biochem Physiol B Biochem Mol Biol. 2012 Sep;163(1):26-36. doi: 10.1016/j.cbpb.2012.05.006. Epub 2012 May 18. Review.

PMID:
22613819
7.

Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression.

Dai L, Trillo-Tinoco J, Bai A, Chen Y, Bielawski J, Del Valle L, Smith CD, Ochoa AC, Qin Z, Parsons C.

Oncotarget. 2015 Sep 15;6(27):24246-60.

8.
9.

Sphingosine kinase and sphingosine 1-phosphate in asthma.

Lai WQ, Wong WS, Leung BP.

Biosci Rep. 2011 Apr;31(2):145-50. doi: 10.1042/BSR20100087. Review.

PMID:
21091442
10.

Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease.

Gangoiti P, Camacho L, Arana L, Ouro A, Granado MH, Brizuela L, Casas J, Fabriás G, Abad JL, Delgado A, Gómez-Muñoz A.

Prog Lipid Res. 2010 Oct;49(4):316-34. doi: 10.1016/j.plipres.2010.02.004. Epub 2010 Mar 1. Review.

PMID:
20193711
11.

Regulation of de novo sphingolipid biosynthesis by the ORMDL proteins and sphingosine kinase-1.

Siow D, Sunkara M, Morris A, Wattenberg B.

Adv Biol Regul. 2015 Jan;57:42-54. doi: 10.1016/j.jbior.2014.09.002. Epub 2014 Sep 17. Review.

PMID:
25319495
12.

Sphingolipids in macroautophagy.

Lavieu G, Scarlatti F, Sala G, Carpentier S, Levade T, Ghidoni R, Botti J, Codogno P.

Methods Mol Biol. 2008;445:159-73. doi: 10.1007/978-1-59745-157-4_11.

PMID:
18425450
13.

Differential branching of the sphingolipid metabolic pathways with the stage of development. Involvement of sphingosine kinase.

Facchinetti MM, Beuret C, Marquez MG, Sterin-Speziale N.

Biol Neonate. 2003;84(3):243-51.

PMID:
14504448
14.

Sphingosine kinases, sphingosine-1-phosphate and sphingolipidomics.

Maceyka M, Milstien S, Spiegel S.

Prostaglandins Other Lipid Mediat. 2005 Sep;77(1-4):15-22. Review.

PMID:
16099387
15.

Activation of sphingosine kinase-1 in cancer: implications for therapeutic targeting.

Cuvillier O, Ader I, Bouquerel P, Brizuela L, Malavaud B, Mazerolles C, Rischmann P.

Curr Mol Pharmacol. 2010 Jun;3(2):53-65. Review.

PMID:
20302564
16.

Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling.

Maceyka M, Milstien S, Spiegel S.

J Lipid Res. 2009 Apr;50 Suppl:S272-6. doi: 10.1194/jlr.R800065-JLR200. Epub 2008 Nov 5. Review.

17.

Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts.

Bu S, Yamanaka M, Pei H, Bielawska A, Bielawski J, Hannun YA, Obeid L, Trojanowska M.

FASEB J. 2006 Jan;20(1):184-6. Epub 2005 Nov 8.

PMID:
16278291
18.

Sphingosine 1-phosphate-metabolizing enzymes control influenza virus propagation and viral cytopathogenicity.

Seo YJ, Blake C, Alexander S, Hahm B.

J Virol. 2010 Aug;84(16):8124-31. doi: 10.1128/JVI.00510-10. Epub 2010 Jun 2.

19.

K6PC-5, a sphingosine kinase activator, induces anti-aging effects in intrinsically aged skin through intracellular Ca2+ signaling.

Youm JK, Jo H, Hong JH, Shin DM, Kwon MJ, Jeong SK, Park BD, Choi EH, Lee SH.

J Dermatol Sci. 2008 Aug;51(2):89-102. doi: 10.1016/j.jdermsci.2008.03.002. Epub 2008 Apr 16.

PMID:
18420384
20.

Biochemical methods for quantifying sphingolipids: ceramide, sphingosine, sphingosine kinase-1 activity, and sphingosine-1-phosphate.

Brizuela L, Cuvillier O.

Methods Mol Biol. 2012;874:1-20. doi: 10.1007/978-1-61779-800-9_1.

PMID:
22528435

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