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Bilirubin possesses powerful immunomodulatory activity and suppresses experimental autoimmune encephalomyelitis.

Liu Y, Li P, Lu J, Xiong W, Oger J, Tetzlaff W, Cynader M.

J Immunol. 2008 Aug 1;181(3):1887-97.


Loss of the surface antigen 3G11 characterizes a distinct population of anergic/regulatory T cells in experimental autoimmune encephalomyelitis.

Zhang GX, Yu S, Calida D, Zhao Z, Gran B, Kamoun M, Rostami A.

J Immunol. 2006 Mar 15;176(6):3366-73.


Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis.

Wang Y, Mei Y, Feng D, Xu L.

J Neurosci Res. 2008 Aug 15;86(11):2441-9. doi: 10.1002/jnr.21683.


Inhibition of invariant chain processing, antigen-induced proliferative responses, and the development of collagen-induced arthritis and experimental autoimmune encephalomyelitis by a small molecule cysteine protease inhibitor.

Podolin PL, Bolognese BJ, Carpenter DC, Davis TG, Johanson RA, Fox JH, Long E 3rd, Dong X, Marquis RW, Locastro SM, Terfloth GJ, Kurali E, Peterson JJ, Smith BR, McQueney MS, Yamashita DS, Capper-Spudich EA.

J Immunol. 2008 Jun 15;180(12):7989-8003.


Activation and control of pathogenic T cells in OSP/claudin-11-induced EAE in SJL/J mice are dominated by their focused recognition of a single epitopic residue (OSP58M).

Kaushansky N, Eisenstein M, Oved JH, Ben-Nun A.

Int Immunol. 2008 Nov;20(11):1439-49. doi: 10.1093/intimm/dxn099. Epub 2008 Sep 18.


Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite.

Platten M, Ho PP, Youssef S, Fontoura P, Garren H, Hur EM, Gupta R, Lee LY, Kidd BA, Robinson WH, Sobel RA, Selley ML, Steinman L.

Science. 2005 Nov 4;310(5749):850-5. Erratum in: Science. 2006 Feb 17;311(5763):954.


Anti-inflammatory effects of plumbagin are mediated by inhibition of NF-kappaB activation in lymphocytes.

Checker R, Sharma D, Sandur SK, Khanam S, Poduval TB.

Int Immunopharmacol. 2009 Jul;9(7-8):949-58. doi: 10.1016/j.intimp.2009.03.022. Epub 2009 Apr 15.


Differential modulation of CNS-specific effector and regulatory T cells during tolerance induction by recombinant invariant chains in vivo.

Lange C, Doster H, Steinbach K, Kalbacher H, Scholl M, Melms A, Bischof F.

Brain Behav Immun. 2009 Aug;23(6):861-7. doi: 10.1016/j.bbi.2009.04.002. Epub 2009 Apr 9.


Biliverdin reductase, a major physiologic cytoprotectant, suppresses experimental autoimmune encephalomyelitis.

Liu Y, Liu J, Tetzlaff W, Paty DW, Cynader MS.

Free Radic Biol Med. 2006 Mar 15;40(6):960-7. Epub 2005 Oct 17.


Oral administration of 1,4-aryl-2-mercaptoimidazole inhibits T-cell proliferation and reduces clinical severity in the murine experimental autoimmune encephalomyelitis model.

Jung EJ, Hur M, Kim YL, Lee GH, Kim J, Kim I, Lee M, Han HK, Kim MS, Hwang S, Kim S, Woo AM, Yoon Y, Park HJ, Won J.

J Pharmacol Exp Ther. 2009 Dec;331(3):1005-13. doi: 10.1124/jpet.109.154948. Epub 2009 Sep 9.


Early life exposure to lipopolysaccharide suppresses experimental autoimmune encephalomyelitis by promoting tolerogenic dendritic cells and regulatory T cells.

Ellestad KK, Tsutsui S, Noorbakhsh F, Warren KG, Yong VW, Pittman QJ, Power C.

J Immunol. 2009 Jul 1;183(1):298-309. doi: 10.4049/jimmunol.0803576.


Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation.

Pierau M, Engelmann S, Reinhold D, Lapp T, Schraven B, Bommhardt UH.

J Immunol. 2009 Nov 15;183(10):6124-34. doi: 10.4049/jimmunol.0900246. Epub 2009 Oct 19.


Vra4 congenic rats with allelic differences in the class II transactivator gene display altered susceptibility to experimental autoimmune encephalomyelitis.

Harnesk K, Swanberg M, Ockinger J, Diez M, Lidman O, Wallström E, Lobell A, Olsson T, Piehl F.

J Immunol. 2008 Mar 1;180(5):3289-96.


Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation.

Wong VK, Zhou H, Cheung SS, Li T, Liu L.

J Cell Biochem. 2009 May 15;107(2):303-15. doi: 10.1002/jcb.22126.


CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells.

Meiron M, Zohar Y, Anunu R, Wildbaum G, Karin N.

J Exp Med. 2008 Oct 27;205(11):2643-55. doi: 10.1084/jem.20080730. Epub 2008 Oct 13.


Gamma-aminobutyric acid transporter 1 negatively regulates T cell-mediated immune responses and ameliorates autoimmune inflammation in the CNS.

Wang Y, Feng D, Liu G, Luo Q, Xu Y, Lin S, Fei J, Xu L.

J Immunol. 2008 Dec 15;181(12):8226-36. Erratum in: J Immunol. 2009 Feb 1;182(3):1772.


CD4+ Th-APC with acquired peptide/MHC class I and II complexes stimulate type 1 helper CD4+ and central memory CD8+ T cell responses.

Umeshappa CS, Huang H, Xie Y, Wei Y, Mulligan SJ, Deng Y, Xiang J.

J Immunol. 2009 Jan 1;182(1):193-206.

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