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Synergistic effects of multiple natural products in pancreatic cancer cells.

Wang Z, Desmoulin S, Banerjee S, Kong D, Li Y, Deraniyagala RL, Abbruzzese J, Sarkar FH.

Life Sci. 2008 Aug 15;83(7-8):293-300. doi: 10.1016/j.lfs.2008.06.017. Epub 2008 Jun 28.


Mechanisms of curcumin- and EGF-receptor related protein (ERRP)-dependent growth inhibition of colon cancer cells.

Reddy S, Rishi AK, Xu H, Levi E, Sarkar FH, Majumdar AP.

Nutr Cancer. 2006;55(2):185-94.


Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells.

Li Y, Ahmed F, Ali S, Philip PA, Kucuk O, Sarkar FH.

Cancer Res. 2005 Aug 1;65(15):6934-42. Erratum in: Cancer Res. 2005 Dec 1;65(23):11228.


Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells.

Wang Z, Zhang Y, Banerjee S, Li Y, Sarkar FH.

Int J Cancer. 2006 Apr 15;118(8):1930-6. Erratum in: Int J Cancer. 2016 Nov 1;139(9):2145. Int J Cancer. 2014 Apr 15;134(8):E3. Retraction in: Int J Cancer. 2016 Nov 1;139(9):2145.


Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer through the downregulation of NF-kappaB and upregulation of TRAIL receptors.

Kamat AM, Tharakan ST, Sung B, Aggarwal BB.

Cancer Res. 2009 Dec 1;69(23):8958-66. doi: 10.1158/0008-5472.CAN-09-2045. Epub 2009 Nov 10.


Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer.

Banerjee S, Zhang Y, Ali S, Bhuiyan M, Wang Z, Chiao PJ, Philip PA, Abbruzzese J, Sarkar FH.

Cancer Res. 2005 Oct 1;65(19):9064-72.


Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.

Aggarwal BB, Shishodia S, Takada Y, Banerjee S, Newman RA, Bueso-Ramos CE, Price JE.

Clin Cancer Res. 2005 Oct 15;11(20):7490-8.


Concurrent inhibition of NF-kappaB, cyclooxygenase-2, and epidermal growth factor receptor leads to greater anti-tumor activity in pancreatic cancer.

Ali S, Banerjee S, Schaffert JM, El-Rayes BF, Philip PA, Sarkar FH.

J Cell Biochem. 2010 May;110(1):171-81. doi: 10.1002/jcb.22523. Erratum in: J Cell Biochem. 2016 Aug;117(8):1961.


Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model.

Kunnumakkara AB, Diagaradjane P, Anand P, Harikumar KB, Deorukhkar A, Gelovani J, Guha S, Krishnan S, Aggarwal BB.

Int J Cancer. 2009 Nov 1;125(9):2187-97. doi: 10.1002/ijc.24593. Erratum in: Int J Cancer. 2010 Feb 1;126(3):799. Kuzhuvelil, Harikumar B [corrected to Harikumar, Kuzhuvelil B].


Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity.

Sandur SK, Deorukhkar A, Pandey MK, Pabón AM, Shentu S, Guha S, Aggarwal BB, Krishnan S.

Int J Radiat Oncol Biol Phys. 2009 Oct 1;75(2):534-42. doi: 10.1016/j.ijrobp.2009.06.034.


The effects of curcumin on proliferation, apoptosis, invasion, and NEDD4 expression in pancreatic cancer.

Su J, Zhou X, Yin X, Wang L, Zhao Z, Hou Y, Zheng N, Xia J, Wang Z.

Biochem Pharmacol. 2017 Sep 15;140:28-40. doi: 10.1016/j.bcp.2017.05.014. Epub 2017 May 20.


Plumbagin, a plant derived natural agent inhibits the growth of pancreatic cancer cells in in vitro and in vivo via targeting EGFR, Stat3 and NF-κB signaling pathways.

Hafeez BB, Jamal MS, Fischer JW, Mustafa A, Verma AK.

Int J Cancer. 2012 Nov 1;131(9):2175-86. doi: 10.1002/ijc.27478. Epub 2012 Mar 20.


Curcumin synergizes the growth inhibitory properties of Indian toad (Bufo melanostictus Schneider) skin-derived factor (BM-ANF1) in HCT-116 colon cancer cells.

Giri B, Gomes A, Sengupta R, Banerjee S, Nautiyal J, Sarkar FH, Majumdar AP.

Anticancer Res. 2009 Jan;29(1):395-401.


Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model.

Sung B, Kunnumakkara AB, Sethi G, Anand P, Guha S, Aggarwal BB.

Mol Cancer Ther. 2009 Apr;8(4):959-70. doi: 10.1158/1535-7163.MCT-08-0905. Erratum in: Mol Cancer Ther. 2009 May;8(5):1398.


Curcumin synergizes with resveratrol to inhibit colon cancer.

Majumdar AP, Banerjee S, Nautiyal J, Patel BB, Patel V, Du J, Yu Y, Elliott AA, Levi E, Sarkar FH.

Nutr Cancer. 2009;61(4):544-53. doi: 10.1080/01635580902752262.


Induction of cancer cell death by isoflavone: the role of multiple signaling pathways.

Li Y, Kong D, Bao B, Ahmad A, Sarkar FH.

Nutrients. 2011 Oct;3(10):877-96. doi: 10.3390/nu3100877. Review.


Pristimerin causes G1 arrest, induces apoptosis, and enhances the chemosensitivity to gemcitabine in pancreatic cancer cells.

Wang Y, Zhou Y, Zhou H, Jia G, Liu J, Han B, Cheng Z, Jiang H, Pan S, Sun B.

PLoS One. 2012;7(8):e43826. doi: 10.1371/journal.pone.0043826. Epub 2012 Aug 28.

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