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Items: 1 to 20 of 110

1.

Effects of anti-microtubule agents on microtubule organization in cells lacking the kinesin-13 MCAK.

Hedrick DG, Stout JR, Walczak CE.

Cell Cycle. 2008 Jul 15;7(14):2146-56. Epub 2008 May 7.

PMID:
18635958
2.

MCAK and paclitaxel have differential effects on spindle microtubule organization and dynamics.

Rizk RS, Bohannon KP, Wetzel LA, Powers J, Shaw SL, Walczak CE.

Mol Biol Cell. 2009 Mar;20(6):1639-51. doi: 10.1091/mbc.E08-09-0985. Epub 2009 Jan 21.

3.

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.

Sanhaji M, Friel CT, Wordeman L, Louwen F, Yuan J.

Oncotarget. 2011 Dec;2(12):935-47. Review.

4.

PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity.

Zhang L, Shao H, Huang Y, Yan F, Chu Y, Hou H, Zhu M, Fu C, Aikhionbare F, Fang G, Ding X, Yao X.

J Biol Chem. 2011 Jan 28;286(4):3033-46. doi: 10.1074/jbc.M110.165340. Epub 2010 Nov 15.

5.

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance.

Ganguly A, Yang H, Pedroza M, Bhattacharya R, Cabral F.

J Biol Chem. 2011 Oct 21;286(42):36378-84. doi: 10.1074/jbc.M111.296483. Epub 2011 Sep 7.

6.

Interplay of microtubule dynamics and sliding during bipolar spindle formation in mammalian cells.

Kollu S, Bakhoum SF, Compton DA.

Curr Biol. 2009 Dec 29;19(24):2108-13. doi: 10.1016/j.cub.2009.10.056.

7.

The interplay of the N- and C-terminal domains of MCAK control microtubule depolymerization activity and spindle assembly.

Ems-McClung SC, Hertzer KM, Zhang X, Miller MW, Walczak CE.

Mol Biol Cell. 2007 Jan;18(1):282-94. Epub 2006 Nov 8.

8.

Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments.

Kline-Smith SL, Khodjakov A, Hergert P, Walczak CE.

Mol Biol Cell. 2004 Mar;15(3):1146-59. Epub 2003 Dec 29.

9.
10.

MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment.

Domnitz SB, Wagenbach M, Decarreau J, Wordeman L.

J Cell Biol. 2012 Apr 16;197(2):231-7. doi: 10.1083/jcb.201108147. Epub 2012 Apr 9.

11.

Overexpression of mitotic centromere-associated Kinesin stimulates microtubule detachment and confers resistance to paclitaxel.

Ganguly A, Yang H, Cabral F.

Mol Cancer Ther. 2011 Jun;10(6):929-37. doi: 10.1158/1535-7163.MCT-10-1109. Epub 2011 Apr 6.

12.

The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.

Manning AL, Ganem NJ, Bakhoum SF, Wagenbach M, Wordeman L, Compton DA.

Mol Biol Cell. 2007 Aug;18(8):2970-9. Epub 2007 May 30.

13.

MCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics.

Barr AR, Gergely F.

Mol Cell Biol. 2008 Dec;28(23):7199-211. doi: 10.1128/MCB.01040-08. Epub 2008 Sep 22.

14.

Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied.

Brito DA, Yang Z, Rieder CL.

J Cell Biol. 2008 Aug 25;182(4):623-9. doi: 10.1083/jcb.200805072. Epub 2008 Aug 18.

16.

Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK.

Cross MK, Powers MA.

Mol Biol Cell. 2011 Mar 1;22(5):661-72. doi: 10.1091/mbc.E10-06-0478. Epub 2011 Jan 5.

17.

Deciphering protein function during mitosis in PtK cells using RNAi.

Stout JR, Rizk RS, Kline SL, Walczak CE.

BMC Cell Biol. 2006 Jun 23;7:26.

18.

Functional and spatial regulation of mitotic centromere-associated kinesin by cyclin-dependent kinase 1.

Sanhaji M, Friel CT, Kreis NN, Krämer A, Martin C, Howard J, Strebhardt K, Yuan J.

Mol Cell Biol. 2010 Jun;30(11):2594-607. doi: 10.1128/MCB.00098-10. Epub 2010 Apr 5.

19.

The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.

Welburn JP, Cheeseman IM.

Mol Biol Cell. 2012 Dec;23(24):4786-95. doi: 10.1091/mbc.E12-03-0214. Epub 2012 Oct 19.

20.

Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function.

Zhang X, Lan W, Ems-McClung SC, Stukenberg PT, Walczak CE.

Mol Biol Cell. 2007 Sep;18(9):3264-76. Epub 2007 Jun 13.

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