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Items: 1 to 20 of 101

1.

Splice variant-dependent regulation of beta-cell sodium-calcium exchange by acyl-coenzyme As.

Hamming KS, Riedel MJ, Soliman D, Matemisz LC, Webster NJ, Searle GJ, MacDonald PE, Light PE.

Mol Endocrinol. 2008 Oct;22(10):2293-306. doi: 10.1210/me.2008-0053. Epub 2008 Jul 17.

2.

Reactive oxygen species directly modify sodium-calcium exchanger activity in a splice variant-dependent manner.

Soliman D, Hamming KS, Matemisz LC, Light PE.

J Mol Cell Cardiol. 2009 Nov;47(5):595-602. doi: 10.1016/j.yjmcc.2009.05.011. Epub 2009 May 28.

PMID:
19481548
3.

Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.

Hamming KS, Soliman D, Webster NJ, Searle GJ, Matemisz LC, Liknes DA, Dai XQ, Pulinilkunnil T, Riedel MJ, Dyck JR, Macdonald PE, Light PE.

Diabetes. 2010 Jul;59(7):1686-93. doi: 10.2337/db09-0630. Epub 2010 Apr 22.

4.

Metabolic regulation of sodium-calcium exchange by intracellular acyl CoAs.

Riedel MJ, Baczkó I, Searle GJ, Webster N, Fercho M, Jones L, Lang J, Lytton J, Dyck JR, Light PE.

EMBO J. 2006 Oct 4;25(19):4605-14. Epub 2006 Sep 14.

5.
6.

NCX1 Na/Ca exchanger splice variants in pancreatic islet cells.

Van Eylen F, Bollen A, Herchuelz A.

J Endocrinol. 2001 Mar;168(3):517-26.

PMID:
11241183
7.

Ionic regulatory properties of brain and kidney splice variants of the NCX1 Na(+)-Ca(2+) exchanger.

Dyck C, Omelchenko A, Elias CL, Quednau BD, Philipson KD, Hnatowich M, Hryshko LV.

J Gen Physiol. 1999 Nov;114(5):701-11.

8.

Three Na+/Ca2+ exchanger (NCX) variants are expressed in mouse osteoclasts and mediate calcium transport during bone resorption.

Li JP, Kajiya H, Okamoto F, Nakao A, Iwamoto T, Okabe K.

Endocrinology. 2007 May;148(5):2116-25. Epub 2007 Feb 22.

PMID:
17317768
9.

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism.

Hilge M, Aelen J, Foarce A, Perrakis A, Vuister GW.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14333-8. doi: 10.1073/pnas.0902171106. Epub 2009 Aug 10.

10.

Intracellular long-chain acyl CoAs activate TRPV1 channels.

Yu Y, Carter CR, Youssef N, Dyck JR, Light PE.

PLoS One. 2014 May 5;9(5):e96597. doi: 10.1371/journal.pone.0096597. eCollection 2014. Erratum in: PLoS One. 2015;10(2):e0118385.

11.

Na(+)/Ca (2+) exchange and the plasma membrane Ca(2+)-ATPase in β-cell function and diabetes.

Herchuelz A, Nguidjoe E, Jiang L, Pachera N.

Adv Exp Med Biol. 2013;961:385-94. doi: 10.1007/978-1-4614-4756-6_33. Review.

PMID:
23224897
12.

Elevation in intracellular long-chain acyl-coenzyme A esters lead to reduced beta-cell excitability via activation of adenosine 5'-triphosphate-sensitive potassium channels.

Webster NJ, Searle GJ, Lam PP, Huang YC, Riedel MJ, Harb G, Gaisano HY, Holt A, Light PE.

Endocrinology. 2008 Jul;149(7):3679-87. doi: 10.1210/en.2007-1138. Epub 2008 Mar 27.

PMID:
18372336
13.

μ-Calpain-mediated deregulation of cardiac, brain, and kidney NCX1 splice variants.

Hnatowich M, Le HD, DeMoissac D, Ranson K, Yurkov V, Gilchrist JS, Omelchenko A, Hryshko LV.

Cell Calcium. 2012 Feb;51(2):164-70. doi: 10.1016/j.ceca.2011.12.006. Epub 2011 Dec 30.

PMID:
22209698
14.

Structure-dynamic determinants governing a mode of regulatory response and propagation of allosteric signal in splice variants of Na+/Ca2+ exchange (NCX) proteins.

Giladi M, Lee SY, Hiller R, Chung KY, Khananshvili D.

Biochem J. 2015 Feb 1;465(3):489-501. doi: 10.1042/BJ20141036.

PMID:
25387769
15.

Structure-Dynamic Coupling Through Ca2+-Binding Regulatory Domains of Mammalian NCX Isoform/Splice Variants.

Khananshvili D.

Adv Exp Med Biol. 2017;981:41-58. doi: 10.1007/978-3-319-55858-5_3. Review.

PMID:
29594857
16.

Cells expressing unique Na+/Ca2+ exchange (NCX1) splice variants exhibit different susceptibilities to Ca2+ overload.

Hurtado C, Prociuk M, Maddaford TG, Dibrov E, Mesaeli N, Hryshko LV, Pierce GN.

Am J Physiol Heart Circ Physiol. 2006 May;290(5):H2155-62. Epub 2006 Jan 6.

17.

Increased bone resorption by osteoclast-specific deletion of the sodium/calcium exchanger isoform 1 (NCX1).

Albano G, Dolder S, Siegrist M, Mercier-Zuber A, Auberson M, Stoudmann C, Hofstetter W, Bonny O, Fuster DG.

Pflugers Arch. 2017 Feb;469(2):225-233. doi: 10.1007/s00424-016-1923-5. Epub 2016 Dec 9.

PMID:
27942992
18.

Tissue specificity and alternative splicing of the Na+/Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat.

Quednau BD, Nicoll DA, Philipson KD.

Am J Physiol. 1997 Apr;272(4 Pt 1):C1250-61.

PMID:
9142850
19.

The molecular determinants of ionic regulatory differences between brain and kidney Na+/Ca2+ exchanger (NCX1) isoforms.

Dunn J, Elias CL, Le HD, Omelchenko A, Hryshko LV, Lytton J.

J Biol Chem. 2002 Sep 13;277(37):33957-62. Epub 2002 Jul 12.

20.

A new cell-penetrating peptide that blocks the autoinhibitory XIP domain of NCX1 and enhances antiporter activity.

Molinaro P, Pannaccione A, Sisalli MJ, Secondo A, Cuomo O, Sirabella R, Cantile M, Ciccone R, Scorziello A, di Renzo G, Annunziato L.

Mol Ther. 2015 Mar;23(3):465-76. doi: 10.1038/mt.2014.231. Epub 2014 Dec 11.

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