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Items: 1 to 20 of 183

1.

Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells.

McGarvey KM, Van Neste L, Cope L, Ohm JE, Herman JG, Van Criekinge W, Schuebel KE, Baylin SB.

Cancer Res. 2008 Jul 15;68(14):5753-9. doi: 10.1158/0008-5472.CAN-08-0700.

2.

A DNA hypermethylation module for the stem/progenitor cell signature of cancer.

Easwaran H, Johnstone SE, Van Neste L, Ohm J, Mosbruger T, Wang Q, Aryee MJ, Joyce P, Ahuja N, Weisenberger D, Collisson E, Zhu J, Yegnasubramanian S, Matsui W, Baylin SB.

Genome Res. 2012 May;22(5):837-49. doi: 10.1101/gr.131169.111. Epub 2012 Mar 5.

3.

PcG proteins, DNA methylation, and gene repression by chromatin looping.

Tiwari VK, McGarvey KM, Licchesi JD, Ohm JE, Herman JG, Schübeler D, Baylin SB.

PLoS Biol. 2008 Dec 2;6(12):2911-27. doi: 10.1371/journal.pbio.0060306.

4.

Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells.

Rodriguez J, Muñoz M, Vives L, Frangou CG, Groudine M, Peinado MA.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19809-14. doi: 10.1073/pnas.0810133105. Epub 2008 Dec 5.

5.
6.

Bivalent histone modifications in stem cells poise miRNA loci for CpG island hypermethylation in human cancer.

Iliou MS, Lujambio A, Portela A, Brüstle O, Koch P, Andersson-Vincent PH, Sundström E, Hovatta O, Esteller M.

Epigenetics. 2011 Nov;6(11):1344-53. doi: 10.4161/epi.6.11.18021. Epub 2011 Nov 1.

PMID:
22048248
7.

Chromatin states of developmentally-regulated genes revealed by DNA and histone methylation patterns in zebrafish embryos.

Lindeman LC, Winata CL, Aanes H, Mathavan S, Alestrom P, Collas P.

Int J Dev Biol. 2010;54(5):803-13. doi: 10.1387/ijdb.103081ll.

8.

Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia.

Magdinier F, Wolffe AP.

Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):4990-5. Epub 2001 Apr 17.

9.

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.

Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, Herman JG, Baylin SB.

Nat Genet. 2007 Feb;39(2):237-42. Epub 2007 Jan 9.

10.

Long range epigenetic silencing is a trans-species mechanism that results in cancer specific deregulation by overriding the chromatin domains of normal cells.

Forn M, Muñoz M, Tauriello DV, Merlos-Suárez A, Rodilla V, Bigas A, Batlle E, Jordà M, Peinado MA.

Mol Oncol. 2013 Dec;7(6):1129-41. doi: 10.1016/j.molonc.2013.08.008. Epub 2013 Aug 30.

11.

An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic research.

Court F, Arnaud P.

Oncotarget. 2017 Jan 17;8(3):4110-4124. doi: 10.18632/oncotarget.13746.

12.

Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk.

Brinkman AB, Gu H, Bartels SJ, Zhang Y, Matarese F, Simmer F, Marks H, Bock C, Gnirke A, Meissner A, Stunnenberg HG.

Genome Res. 2012 Jun;22(6):1128-38. doi: 10.1101/gr.133728.111. Epub 2012 Mar 30.

13.

DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis.

Foltz G, Yoon JG, Lee H, Ryken TC, Sibenaller Z, Ehrich M, Hood L, Madan A.

Oncogene. 2009 Jul 23;28(29):2667-77. doi: 10.1038/onc.2009.122. Epub 2009 May 25.

PMID:
19465937
14.

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island.

O'Hagan HM, Mohammad HP, Baylin SB.

PLoS Genet. 2008 Aug 15;4(8):e1000155. doi: 10.1371/journal.pgen.1000155.

15.
16.

Aberrant silencing of cancer-related genes by CpG hypermethylation occurs independently of their spatial organization in the nucleus.

Easwaran HP, Van Neste L, Cope L, Sen S, Mohammad HP, Pageau GJ, Lawrence JB, Herman JG, Schuebel KE, Baylin SB.

Cancer Res. 2010 Oct 15;70(20):8015-24. doi: 10.1158/0008-5472.CAN-10-0765. Epub 2010 Aug 24.

17.
18.

Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.

Derks S, Bosch LJ, Niessen HE, Moerkerk PT, van den Bosch SM, Carvalho B, Mongera S, Voncken JW, Meijer GA, de Bruïne AP, Herman JG, van Engeland M.

Carcinogenesis. 2009 Jun;30(6):1041-8. doi: 10.1093/carcin/bgp073. Epub 2009 Mar 27.

PMID:
19329758
19.

Genes Predisposed to DNA Hypermethylation during Acquired Resistance to Chemotherapy Are Identified in Ovarian Tumors by Bivalent Chromatin Domains at Initial Diagnosis.

Curry E, Zeller C, Masrour N, Patten DK, Gallon J, Wilhelm-Benartzi CS, Ghaem-Maghami S, Bowtell DD, Brown R.

Cancer Res. 2018 Mar 15;78(6):1383-1391. doi: 10.1158/0008-5472.CAN-17-1650. Epub 2018 Jan 16.

20.

Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer.

Yan PS, Shi H, Rahmatpanah F, Hsiau TH, Hsiau AH, Leu YW, Liu JC, Huang TH.

Cancer Res. 2003 Oct 1;63(19):6178-86.

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