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Items: 1 to 20 of 83

1.

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice.

Strong R, Miller RA, Astle CM, Floyd RA, Flurkey K, Hensley KL, Javors MA, Leeuwenburgh C, Nelson JF, Ongini E, Nadon NL, Warner HR, Harrison DE.

Aging Cell. 2008 Oct;7(5):641-50. doi: 10.1111/j.1474-9726.2008.00414.x.

PMID:
18631321
2.

An Aging Interventions Testing Program: study design and interim report.

Miller RA, Harrison DE, Astle CM, Floyd RA, Flurkey K, Hensley KL, Javors MA, Leeuwenburgh C, Nelson JF, Ongini E, Nadon NL, Warner HR, Strong R.

Aging Cell. 2007 Aug;6(4):565-75. Epub 2007 Jun 18. Erratum in: Aging Cell. 2008 Jun;7(3):445.

PMID:
17578509
3.

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males.

Harrison DE, Strong R, Allison DB, Ames BN, Astle CM, Atamna H, Fernandez E, Flurkey K, Javors MA, Nadon NL, Nelson JF, Pletcher S, Simpkins JW, Smith D, Wilkinson JE, Miller RA.

Aging Cell. 2014 Apr;13(2):273-82. doi: 10.1111/acel.12170. Epub 2013 Nov 19.

PMID:
24245565
4.

Life extension by diet restriction and N-acetyl-L-cysteine in genetically heterogeneous mice.

Flurkey K, Astle CM, Harrison DE.

J Gerontol A Biol Sci Med Sci. 2010 Dec;65(12):1275-84. doi: 10.1093/gerona/glq155. Epub 2010 Sep 5.

PMID:
20819793
5.

Nordihydroguaiaretic Acid Extends the Lifespan of Drosophila and Mice, Increases Mortality-Related Tumors and Hemorrhagic Diathesis, and Alters Energy Homeostasis in Mice.

Spindler SR, Mote PL, Lublin AL, Flegal JM, Dhahbi JM, Li R.

J Gerontol A Biol Sci Med Sci. 2015 Dec;70(12):1479-89. doi: 10.1093/gerona/glu190. Epub 2014 Nov 7.

PMID:
25380600
6.

Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice.

Strong R, Miller RA, Astle CM, Baur JA, de Cabo R, Fernandez E, Guo W, Javors M, Kirkland JL, Nelson JF, Sinclair DA, Teter B, Williams D, Zaveri N, Nadon NL, Harrison DE.

J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):6-16. doi: 10.1093/gerona/gls070. Epub 2012 Mar 26.

PMID:
22451473
7.

Reduction in primary nonfunction of syngeneic islet transplants with nordihydroguaiaretic acid, a lipoxygenase inhibitor.

Hsu BR, Juang JH, Fu SH, Kuo CH, Lu WT.

Cell Transplant. 2001;10(3):255-62.

PMID:
11437071
8.

Conjugated linoleic acid-induced fat loss dependence on Delta6-desaturase or cyclooxygenase.

Hargrave-Barnes KM, Azain MJ, Miner JL.

Obesity (Silver Spring). 2008 Oct;16(10):2245-52. doi: 10.1038/oby.2008.338. Epub 2008 Jul 24.

PMID:
18719641
9.

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.

Miller RA, Harrison DE, Astle CM, Baur JA, Boyd AR, de Cabo R, Fernandez E, Flurkey K, Javors MA, Nelson JF, Orihuela CJ, Pletcher S, Sharp ZD, Sinclair D, Starnes JW, Wilkinson JE, Nadon NL, Strong R.

J Gerontol A Biol Sci Med Sci. 2011 Feb;66(2):191-201. doi: 10.1093/gerona/glq178. Epub 2010 Oct 25.

PMID:
20974732
10.

Paradoxical cellular effects and biological role of the multifaceted compound nordihydroguaiaretic acid.

Hernández-Damián J, Andérica-Romero AC, Pedraza-Chaverri J.

Arch Pharm (Weinheim). 2014 Oct;347(10):685-97. doi: 10.1002/ardp.201400159. Epub 2014 Aug 6. Review.

PMID:
25100573
11.

Lipoxygenase pathway inhibition impairs the allograft response.

Jordan ML, Carlson A, Hoffman RA, Simmons RL.

Surgery. 1987 Aug;102(2):248-55.

PMID:
3039676
12.

Anti-inflammatory effects of specific cyclooxygenase 2,5-lipoxygenase, and inducible nitric oxide synthase inhibitors on experimental autoimmune anterior uveitis (EAAU).

Bora NS, Sohn JH, Bora PS, Kaplan HJ, Kulkarni P.

Ocul Immunol Inflamm. 2005 Apr-Jun;13(2-3):183-9.

PMID:
16019677
13.

Nordihydroguaiaretic acid protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice.

Lee MS, Kim D, Jo K, Hwang JK.

Biochem Biophys Res Commun. 2010 Oct 8;401(1):92-7. doi: 10.1016/j.bbrc.2010.09.016. Epub 2010 Sep 17.

PMID:
20836990
14.

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.

Strong R, Miller RA, Antebi A, Astle CM, Bogue M, Denzel MS, Fernandez E, Flurkey K, Hamilton KL, Lamming DW, Javors MA, de Magalhães JP, Martinez PA, McCord JM, Miller BF, Müller M, Nelson JF, Ndukum J, Rainger GE, Richardson A, Sabatini DM, Salmon AB, Simpkins JW, Steegenga WT, Nadon NL, Harrison DE.

Aging Cell. 2016 Oct;15(5):872-84. doi: 10.1111/acel.12496. Epub 2016 Jun 16.

PMID:
27312235
15.

Hormone levels and cataract scores as sex-specific, mid-life predictors of longevity in genetically heterogeneous mice.

Harper JM, Wolf N, Galecki AT, Pinkosky SL, Miller RA.

Mech Ageing Dev. 2003 Jul;124(7):801-10.

PMID:
12875743
16.

Nordihydroguaiaretic acid: hepatotoxicity and detoxification in the mouse.

Lambert JD, Zhao D, Meyers RO, Kuester RK, Timmermann BN, Dorr RT.

Toxicon. 2002 Dec;40(12):1701-8.

PMID:
12457882
17.

The effects and metabolic fate of nitroflurbiprofen in healthy volunteers.

Zacharowski P, Zacharowski K, Donnellan C, Johnston A, Vojnovic I, Forte P, Del Soldato P, Benjamin N, O'Byrne S.

Clin Pharmacol Ther. 2004 Oct;76(4):350-8.

PMID:
15470334
18.

Effect of a lipoxygenase inhibitor on vasoconstriction in dog lung.

el-Kashef HA, Hofman WF, Ehrhart IC.

Am J Physiol. 1989 Dec;257(6 Pt 2):H1977-82.

PMID:
2513733
20.

Prostaglandin H synthase and lipoxygenase mediated activation of xenobiotics in platelets.

Lim KM, Lee JY, Kim JS, Chung JH.

Adv Exp Med Biol. 1999;469:631-7.

PMID:
10667392

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