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Items: 1 to 20 of 196

1.

High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer.

Simi L, Pratesi N, Vignoli M, Sestini R, Cianchi F, Valanzano R, Nobili S, Mini E, Pazzagli M, Orlando C.

Am J Clin Pathol. 2008 Aug;130(2):247-53. doi: 10.1309/LWDY1AXHXUULNVHQ.

PMID:
18628094
2.

High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer.

Guedes JG, Veiga I, Rocha P, Pinto P, Pinto C, Pinheiro M, Peixoto A, Fragoso M, Raimundo A, Ferreira P, Machado M, Sousa N, Lopes P, Araújo A, Macedo J, Alves F, Coutinho C, Henrique R, Santos LL, Teixeira MR.

BMC Cancer. 2013 Apr 1;13:169. doi: 10.1186/1471-2407-13-169.

3.

Characteristics and prevalence of KRAS, BRAF, and PIK3CA mutations in colorectal cancer by high-resolution melting analysis in Taiwanese population.

Hsieh LL, Er TK, Chen CC, Hsieh JS, Chang JG, Liu TC.

Clin Chim Acta. 2012 Oct 9;413(19-20):1605-11. doi: 10.1016/j.cca.2012.04.029. Epub 2012 May 8.

PMID:
22579930
4.

[Detection of KRAS, BRAF, PIK3CA and EGFR gene mutations in colorectal carcinoma].

Ling Y, Ying JM, Qiu T, Shan L, Guo L, Lü N.

Zhonghua Bing Li Xue Za Zhi. 2012 Sep;41(9):590-4. doi: 10.3760/cma.j.issn.0529-5807.2012.09.004. Chinese.

PMID:
23157825
5.

KRAS, BRAF and PIK3CA mutations in human colorectal cancer: relationship with metastatic colorectal cancer.

Li HT, Lu YY, An YX, Wang X, Zhao QC.

Oncol Rep. 2011 Jun;25(6):1691-7. doi: 10.3892/or.2011.1217. Epub 2011 Mar 17.

PMID:
21424126
6.

Identification of KRAS and PIK3CA but not BRAF mutations in patients with gastric cancer.

Lu W, Wei H, Li M, Wang H, Liu L, Zhang Q, Liu L, Lu S.

Mol Med Rep. 2015 Jul;12(1):1219-24. doi: 10.3892/mmr.2015.3530. Epub 2015 Mar 23.

PMID:
25815786
7.

Molecular alterations of Ras-Raf-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt signaling pathways in colorectal cancers from a tertiary hospital at Kuala Lumpur, Malaysia.

Yip WK, Choo CW, Leong VC, Leong PP, Jabar MF, Seow HF.

APMIS. 2013 Oct;121(10):954-66. doi: 10.1111/apm.12152. Epub 2013 Aug 29.

PMID:
23992303
8.

Mutational profiles of different macroscopic subtypes of colorectal adenoma reveal distinct pathogenetic roles for KRAS, BRAF and PIK3CA.

Chang LC, Chiu HM, Shun CT, Liang JT, Lin JT, Chen CC, Lee YC, Wu MS.

BMC Gastroenterol. 2014 Dec 31;14:221. doi: 10.1186/s12876-014-0221-y.

9.

Survey of KRAS, BRAF and PIK3CA mutational status in 209 consecutive Italian colorectal cancer patients.

Bozzao C, Varvara D, Piglionica M, Bagnulo R, Forte G, Patruno M, Russo S, Piscitelli D, Stella A, Resta N.

Int J Biol Markers. 2012 Dec 27;27(4):e366-74. doi: 10.5301/JBM.2012.9765.

PMID:
23125007
10.

High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues.

Ney JT, Froehner S, Roesler A, Buettner R, Merkelbach-Bruse S.

Arch Pathol Lab Med. 2012 Sep;136(9):983-92. doi: 10.5858/arpa.2011-0176-OA.

PMID:
22938585
11.

Effectors of epidermal growth factor receptor pathway: the genetic profiling ofKRAS, BRAF, PIK3CA, NRAS mutations in colorectal cancer characteristics and personalized medicine.

Shen Y, Wang J, Han X, Yang H, Wang S, Lin D, Shi Y.

PLoS One. 2013 Dec 10;8(12):e81628. doi: 10.1371/journal.pone.0081628. eCollection 2013.

12.

Clinical pharmacogenomic testing of KRAS, BRAF and EGFR mutations by high resolution melting analysis and ultra-deep pyrosequencing.

Borràs E, Jurado I, Hernan I, Gamundi MJ, Dias M, Martí I, Mañé B, Arcusa A, Agúndez JA, Blanca M, Carballo M.

BMC Cancer. 2011 Sep 24;11:406. doi: 10.1186/1471-2407-11-406.

13.

Molecular analysis of PIK3CA, BRAF, and RAS oncogenes in periampullary and ampullary adenomas and carcinomas.

Schönleben F, Qiu W, Allendorf JD, Chabot JA, Remotti HE, Su GH.

J Gastrointest Surg. 2009 Aug;13(8):1510-6. doi: 10.1007/s11605-009-0917-4. Epub 2009 May 14.

14.

PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers.

Janku F, Lee JJ, Tsimberidou AM, Hong DS, Naing A, Falchook GS, Fu S, Luthra R, Garrido-Laguna I, Kurzrock R.

PLoS One. 2011;6(7):e22769. doi: 10.1371/journal.pone.0022769. Epub 2011 Jul 29.

15.

BRAF V600E mutation and KRAS codon 13 mutations predict poor survival in Chinese colorectal cancer patients.

Chen J, Guo F, Shi X, Zhang L, Zhang A, Jin H, He Y.

BMC Cancer. 2014 Nov 3;14:802. doi: 10.1186/1471-2407-14-802.

16.

Concomitant mutations and splice variants in KRAS and BRAF demonstrate complex perturbation of the Ras/Raf signalling pathway in advanced colorectal cancer.

Seth R, Crook S, Ibrahem S, Fadhil W, Jackson D, Ilyas M.

Gut. 2009 Sep;58(9):1234-41. doi: 10.1136/gut.2008.159137. Epub 2009 May 26.

PMID:
19474002
17.

Mutational analyses of the BRAF, KRAS, and PIK3CA genes in oral squamous cell carcinoma.

Bruckman KC, Schönleben F, Qiu W, Woo VL, Su GH.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Nov;110(5):632-7. doi: 10.1016/j.tripleo.2010.05.002. Epub 2010 Sep 1.

18.

Molecular spectrum of KRAS, BRAF, and PIK3CA gene mutation: determination of frequency, distribution pattern in Indian colorectal carcinoma.

Bisht S, Ahmad F, Sawaimoon S, Bhatia S, Das BR.

Med Oncol. 2014 Sep;31(9):124. doi: 10.1007/s12032-014-0124-3. Epub 2014 Jul 30.

PMID:
25073438
19.

BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?

Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C, Seruca R.

BMC Cancer. 2008 Sep 9;8:255. doi: 10.1186/1471-2407-8-255.

20.

Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications.

Kosmidou V, Oikonomou E, Vlassi M, Avlonitis S, Katseli A, Tsipras I, Mourtzoukou D, Kontogeorgos G, Zografos G, Pintzas A.

Hum Mutat. 2014 Mar;35(3):329-40. doi: 10.1002/humu.22496. Epub 2014 Jan 15.

PMID:
24352906

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