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Items: 1 to 20 of 93

1.

Autophagy is an adaptive response in desmin-related cardiomyopathy.

Tannous P, Zhu H, Johnstone JL, Shelton JM, Rajasekaran NS, Benjamin IJ, Nguyen L, Gerard RD, Levine B, Rothermel BA, Hill JA.

Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9745-50. doi: 10.1073/pnas.0706802105. Epub 2008 Jul 9.

2.

Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes.

Pattison JS, Osinska H, Robbins J.

Circ Res. 2011 Jul 8;109(2):151-60. doi: 10.1161/CIRCRESAHA.110.237339. Epub 2011 May 26.

3.

Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy.

Maloyan A, Gulick J, Glabe CG, Kayed R, Robbins J.

Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5995-6000. Epub 2007 Mar 26.

4.

Autophagy and p62 in cardiac proteinopathy.

Zheng Q, Su H, Ranek MJ, Wang X.

Circ Res. 2011 Jul 22;109(3):296-308. doi: 10.1161/CIRCRESAHA.111.244707. Epub 2011 Jun 9.

5.

Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy.

McLendon PM, Ferguson BS, Osinska H, Bhuiyan MS, James J, McKinsey TA, Robbins J.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):E5178-86. doi: 10.1073/pnas.1415589111. Epub 2014 Nov 17.

6.

Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy.

Maloyan A, Sanbe A, Osinska H, Westfall M, Robinson D, Imahashi K, Murphy E, Robbins J.

Circulation. 2005 Nov 29;112(22):3451-61.

7.

Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathy.

Maloyan A, Osinska H, Lammerding J, Lee RT, Cingolani OH, Kass DA, Lorenz JN, Robbins J.

Circ Res. 2009 Apr 24;104(8):1021-8. doi: 10.1161/CIRCRESAHA.108.193516. Epub 2009 Mar 19.

8.

AlphaB-crystallin modulates protein aggregation of abnormal desmin.

Wang X, Klevitsky R, Huang W, Glasford J, Li F, Robbins J.

Circ Res. 2003 Nov 14;93(10):998-1005. Epub 2003 Oct 23.

9.

Manipulation of death pathways in desmin-related cardiomyopathy.

Maloyan A, Sayegh J, Osinska H, Chua BH, Robbins J.

Circ Res. 2010 May 14;106(9):1524-32. doi: 10.1161/CIRCRESAHA.109.212639. Epub 2010 Apr 1.

10.

Doxycycline attenuates protein aggregation in cardiomyocytes and improves survival of a mouse model of cardiac proteinopathy.

Zheng H, Tang M, Zheng Q, Kumarapeli AR, Horak KM, Tian Z, Wang X.

J Am Coll Cardiol. 2010 Oct 19;56(17):1418-26. doi: 10.1016/j.jacc.2010.01.075.

11.

COP9 signalosome controls the degradation of cytosolic misfolded proteins and protects against cardiac proteotoxicity.

Su H, Li J, Zhang H, Ma W, Wei N, Liu J, Wang X.

Circ Res. 2015 Nov 6;117(11):956-66. doi: 10.1161/CIRCRESAHA.115.306783. Epub 2015 Sep 17.

12.

Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis.

Sanbe A, Osinska H, Saffitz JE, Glabe CG, Kayed R, Maloyan A, Robbins J.

Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10132-6. Epub 2004 Jun 25.

13.

Sumo E2 enzyme UBC9 is required for efficient protein quality control in cardiomyocytes.

Gupta MK, Gulick J, Liu R, Wang X, Molkentin JD, Robbins J.

Circ Res. 2014 Sep 26;115(8):721-9. doi: 10.1161/CIRCRESAHA.115.304760. Epub 2014 Aug 5.

14.

Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice.

Wang X, Osinska H, Klevitsky R, Gerdes AM, Nieman M, Lorenz J, Hewett T, Robbins J.

Circ Res. 2001 Jul 6;89(1):84-91.

15.

Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy.

Sanbe A, Osinska H, Villa C, Gulick J, Klevitsky R, Glabe CG, Kayed R, Robbins J.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13592-7. Epub 2005 Sep 9.

16.

Interruption of CryAB-amyloid oligomer formation by HSP22.

Sanbe A, Yamauchi J, Miyamoto Y, Fujiwara Y, Murabe M, Tanoue A.

J Biol Chem. 2007 Jan 5;282(1):555-63. Epub 2006 Nov 8.

17.

Enhanced autophagy ameliorates cardiac proteinopathy.

Bhuiyan MS, Pattison JS, Osinska H, James J, Gulick J, McLendon PM, Hill JA, Sadoshima J, Robbins J.

J Clin Invest. 2013 Dec;123(12):5284-97. doi: 10.1172/JCI70877. Epub 2013 Nov 1.

18.

The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability.

Elliott JL, Der Perng M, Prescott AR, Jansen KA, Koenderink GH, Quinlan RA.

Philos Trans R Soc Lond B Biol Sci. 2013 Mar 25;368(1617):20120375. doi: 10.1098/rstb.2012.0375. Print 2013 May 5.

19.

Molecular mechanisms of α-crystallinopathy and its therapeutic strategy.

Sanbe A.

Biol Pharm Bull. 2011;34(11):1653-8. Review.

20.

p62 expression and autophagy in αB-crystallin R120G mutant knock-in mouse model of hereditary cataract.

Wignes JA, Goldman JW, Weihl CC, Bartley MG, Andley UP.

Exp Eye Res. 2013 Oct;115:263-73. doi: 10.1016/j.exer.2013.06.026. Epub 2013 Jul 18.

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