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Duffy antigen receptor for chemokines mediates trans-infection of HIV-1 from red blood cells to target cells and affects HIV-AIDS susceptibility.

He W, Neil S, Kulkarni H, Wright E, Agan BK, Marconi VC, Dolan MJ, Weiss RA, Ahuja SK.

Cell Host Microbe. 2008 Jul 17;4(1):52-62. doi: 10.1016/j.chom.2008.06.002.


HIV and chemokine binding to red blood cells--DARC matters.

Walton RT, Rowland-Jones SL.

Cell Host Microbe. 2008 Jul 17;4(1):3-5. doi: 10.1016/j.chom.2008.06.006. Review.


Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.

Ramsuran V, Kulkarni H, He W, Mlisana K, Wright EJ, Werner L, Castiblanco J, Dhanda R, Le T, Dolan MJ, Guan W, Weiss RA, Clark RA, Karim SS, Ahuja SK, Ndung'u T.

Clin Infect Dis. 2011 May;52(10):1248-56. doi: 10.1093/cid/cir119.


The Duffy antigen/receptor for chemokines (DARC) is expressed in endothelial cells of Duffy negative individuals who lack the erythrocyte receptor.

Peiper SC, Wang ZX, Neote K, Martin AW, Showell HJ, Conklyn MJ, Ogborne K, Hadley TJ, Lu ZH, Hesselgesser J, Horuk R.

J Exp Med. 1995 Apr 1;181(4):1311-7.


Binding of HIV-1 to RBCs involves the Duffy antigen receptors for chemokines (DARC).

Lachgar A, Jaureguiberry G, Le Buenac H, Bizzini B, Zagury JF, Rappaport J, Zagury D.

Biomed Pharmacother. 1998;52(10):436-9.


Acquired antibody responses against Plasmodium vivax infection vary with host genotype for duffy antigen receptor for chemokines (DARC).

Maestre A, Muskus C, Duque V, Agudelo O, Liu P, Takagi A, Ntumngia FB, Adams JH, Sim KL, Hoffman SL, Corradin G, Velez ID, Wang R.

PLoS One. 2010 Jul 15;5(7):e11437. doi: 10.1371/journal.pone.0011437.


Expression of Duffy antigen receptor for chemokines (DARC) has no effect on HIV-1 acquisition or progression to AIDS in African Americans.

Winkler CA, An P, Johnson R, Nelson GW, Kirk G.

Cell Host Microbe. 2009 May 8;5(5):411-3; author reply 418-9. doi: 10.1016/j.chom.2009.04.010. No abstract available.


The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury.

Kangelaris KN, Sapru A, Calfee CS, Liu KD, Pawlikowska L, Witte JS, Vittinghoff E, Zhuo H, Auerbach AD, Ziv E, Matthay MA; National Heart, Lung, and Blood Institute ARDS Network.

Chest. 2012 May;141(5):1160-1169. doi: 10.1378/chest.11-1766. Epub 2011 Dec 29.


Activation state of alpha4beta1 integrin on sickle red blood cells is linked to the duffy antigen receptor for chemokines (DARC) expression.

Durpès MC, Hardy-Dessources MD, El Nemer W, Picot J, Lemonne N, Elion J, Decastel M.

J Biol Chem. 2011 Jan 28;286(4):3057-64. doi: 10.1074/jbc.M110.173229. Epub 2010 Nov 18.


Duffy blood group and malaria.

Langhi DM Jr, Bordin JO.

Hematology. 2006 Oct;11(5):389-98. Review.


The Duffy-null state is associated with a survival advantage in leukopenic HIV-infected persons of African ancestry.

Kulkarni H, Marconi VC, He W, Landrum ML, Okulicz JF, Delmar J, Kazandjian D, Castiblanco J, Ahuja SS, Wright EJ, Weiss RA, Clark RA, Dolan MJ, Ahuja SK.

Blood. 2009 Sep 24;114(13):2783-92. doi: 10.1182/blood-2009-04-215186. Epub 2009 Jul 20.


Sulphated tyrosines mediate association of chemokines and Plasmodium vivax Duffy binding protein with the Duffy antigen/receptor for chemokines (DARC).

Choe H, Moore MJ, Owens CM, Wright PL, Vasilieva N, Li W, Singh AP, Shakri R, Chitnis CE, Farzan M.

Mol Microbiol. 2005 Mar;55(5):1413-22.


Duffy antigen receptor for chemokine (DARC) polymorphisms and its involvement in acquisition of inhibitory anti-duffy binding protein II (DBPII) immunity.

Souza-Silva FA, Torres LM, Santos-Alves JR, Tang ML, Sanchez BA, Sousa TN, Fontes CJ, Nogueira PA, Rocha RS, Brito CF, Adams JH, Kano FS, Carvalho LH.

PLoS One. 2014 Apr 7;9(4):e93782. doi: 10.1371/journal.pone.0093782. eCollection 2014.


The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth.

Shen H, Schuster R, Stringer KF, Waltz SE, Lentsch AB.

FASEB J. 2006 Jan;20(1):59-64.


Sequence, evolution and ligand binding properties of mammalian Duffy antigen/receptor for chemokines.

Tournamille C, Blancher A, Le Van Kim C, Gane P, Apoil PA, Nakamoto W, Cartron JP, Colin Y.

Immunogenetics. 2004 Jan;55(10):682-94. Epub 2004 Jan 8.


Population genetic analysis of the DARC locus (Duffy) reveals adaptation from standing variation associated with malaria resistance in humans.

McManus KF, Taravella AM, Henn BM, Bustamante CD, Sikora M, Cornejo OE.

PLoS Genet. 2017 Mar 10;13(3):e1006560. doi: 10.1371/journal.pgen.1006560. eCollection 2017 Mar.


Chemokine homeostasis vs. chemokine presentation during severe acute lung injury: the other side of the Duffy antigen receptor for chemokines.

Zarbock A, Bishop J, Müller H, Schmolke M, Buschmann K, Van Aken H, Singbartl K.

Am J Physiol Lung Cell Mol Physiol. 2010 Mar;298(3):L462-71. doi: 10.1152/ajplung.00224.2009. Epub 2010 Jan 8.


Species-specific features of DARC, the primate receptor for Plasmodium vivax and Plasmodium knowlesi.

Demogines A, Truong KA, Sawyer SL.

Mol Biol Evol. 2012 Feb;29(2):445-9. doi: 10.1093/molbev/msr204. Epub 2011 Aug 30.


Up-regulation of Duffy antigen receptor expression in children with renal disease.

Liu XH, Hadley TJ, Xu L, Peiper SC, Ray PE.

Kidney Int. 1999 Apr;55(4):1491-500.


Differential expression of the duffy antigen receptor for chemokines according to RBC age and FY genotype.

Woolley IJ, Hotmire KA, Sramkoski RM, Zimmerman PA, Kazura JW.

Transfusion. 2000 Aug;40(8):949-53.


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