Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 90


The gene expression profile induced by Wnt 3a in NIH 3T3 fibroblasts.

Chen S, McLean S, Carter DE, Leask A.

J Cell Commun Signal. 2007 Dec;1(3-4):175-83. doi: 10.1007/s12079-007-0015-x. Epub 2008 Jan 20.


Wnt 10b activates the CCN2 promoter in NIH 3T3 fibroblasts through the Smad response element.

Chen S, Leask A.

J Cell Commun Signal. 2009 Mar;3(1):57-9. doi: 10.1007/s12079-009-0049-3. Epub 2009 Apr 8.


Fibroblast adhesion results in the induction of a matrix remodeling gene expression program.

Kennedy L, Shi-Wen X, Carter DE, Abraham DJ, Leask A.

Matrix Biol. 2008 May;27(4):274-81. doi: 10.1016/j.matbio.2008.01.004. Epub 2008 Jan 26.


CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts.

Shi-wen X, Stanton LA, Kennedy L, Pala D, Chen Y, Howat SL, Renzoni EA, Carter DE, Bou-Gharios G, Stratton RJ, Pearson JD, Beier F, Lyons KM, Black CM, Abraham DJ, Leask A.

J Biol Chem. 2006 Apr 21;281(16):10715-26. Epub 2006 Feb 16.


Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells.

Wei J, Fang F, Lam AP, Sargent JL, Hamburg E, Hinchcliff ME, Gottardi CJ, Atit R, Whitfield ML, Varga J.

Arthritis Rheum. 2012 Aug;64(8):2734-45. doi: 10.1002/art.34424.


Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells.

Luo Q, Kang Q, Si W, Jiang W, Park JK, Peng Y, Li X, Luu HH, Luo J, Montag AG, Haydon RC, He TC.

J Biol Chem. 2004 Dec 31;279(53):55958-68. Epub 2004 Oct 20.


Mechanical tension increases CCN2/CTGF expression and proliferation in gingival fibroblasts via a TGFβ-dependent mechanism.

Guo F, Carter DE, Leask A.

PLoS One. 2011;6(5):e19756. doi: 10.1371/journal.pone.0019756. Epub 2011 May 17.


CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells.

Si W, Kang Q, Luu HH, Park JK, Luo Q, Song WX, Jiang W, Luo X, Li X, Yin H, Montag AG, Haydon RC, He TC.

Mol Cell Biol. 2006 Apr;26(8):2955-64.


Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblasts.

Shi-Wen X, Renzoni EA, Kennedy L, Howat S, Chen Y, Pearson JD, Bou-Gharios G, Dashwood MR, du Bois RM, Black CM, Denton CP, Abraham DJ, Leask A.

Matrix Biol. 2007 Oct;26(8):625-32. Epub 2007 Jun 18.


Gene array analysis of Wnt-regulated genes in C3H10T1/2 cells.

Jackson A, Vayssière B, Garcia T, Newell W, Baron R, Roman-Roman S, Rawadi G.

Bone. 2005 Apr;36(4):585-98.


Endothelin-1 induces connective tissue growth factor expression in cardiomyocytes.

Recchia AG, Filice E, Pellegrino D, Dobrina A, Cerra MC, Maggiolini M.

J Mol Cell Cardiol. 2009 Mar;46(3):352-9. doi: 10.1016/j.yjmcc.2008.11.017. Epub 2008 Dec 10.


Keloid fibroblasts are more sensitive to Wnt3a treatment in terms of elevated cellular growth and fibronectin expression.

Chua AW, Gan SU, Ting Y, Fu Z, Lim CK, Song C, Sabapathy K, Phan TT.

J Dermatol Sci. 2011 Dec;64(3):199-209. doi: 10.1016/j.jdermsci.2011.09.008. Epub 2011 Sep 29.


Wnt-3a-activated human fibroblasts promote human keratinocyte proliferation and matrix destruction.

Sobel K, Tham M, Stark HJ, Stammer H, Prätzel-Wunder S, Bickenbach JR, Boukamp P.

Int J Cancer. 2015 Jun 15;136(12):2786-98. doi: 10.1002/ijc.29336. Epub 2014 Nov 26.


Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.

Xu SW, Howat SL, Renzoni EA, Holmes A, Pearson JD, Dashwood MR, Bou-Gharios G, Denton CP, du Bois RM, Black CM, Leask A, Abraham DJ.

J Biol Chem. 2004 May 28;279(22):23098-103. Epub 2004 Mar 23.

Supplemental Content

Support Center