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Items: 1 to 20 of 150

1.

SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production.

Green KN, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, LaFerla FM.

J Cell Biol. 2008 Jun 30;181(7):1107-16. doi: 10.1083/jcb.200706171.

2.

Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.

Rivabene R, Visentin S, Piscopo P, De Nuccio C, Crestini A, Svetoni F, Rosa P, Confaloni A.

Exp Biol Med (Maywood). 2014 Feb;239(2):213-24. doi: 10.1177/1535370213514317. Epub 2013 Dec 20.

PMID:
24363250
3.

Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.

Zatti G, Burgo A, Giacomello M, Barbiero L, Ghidoni R, Sinigaglia G, Florean C, Bagnoli S, Binetti G, Sorbi S, Pizzo P, Fasolato C.

Cell Calcium. 2006 Jun;39(6):539-50. Epub 2006 Apr 18.

PMID:
16620965
4.

Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels.

Shilling D, Mak DO, Kang DE, Foskett JK.

J Biol Chem. 2012 Mar 30;287(14):10933-44. doi: 10.1074/jbc.M111.300491. Epub 2012 Feb 6.

5.

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.

Tu H, Nelson O, Bezprozvanny A, Wang Z, Lee SF, Hao YH, Serneels L, De Strooper B, Yu G, Bezprozvanny I.

Cell. 2006 Sep 8;126(5):981-93.

6.

Glucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells.

Dror V, Kalynyak TB, Bychkivska Y, Frey MH, Tee M, Jeffrey KD, Nguyen V, Luciani DS, Johnson JD.

J Biol Chem. 2008 Apr 11;283(15):9909-16. doi: 10.1074/jbc.M710601200. Epub 2008 Jan 3.

7.
8.

Repression of transcription of presenilin-1 inhibits γ-secretase independent ER Ca²⁺ leak that is impaired by FAD mutations.

Das HK, Tchedre K, Mueller B.

J Neurochem. 2012 Aug;122(3):487-500. doi: 10.1111/j.1471-4159.2012.07794.x. Epub 2012 Jun 22.

9.

Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.

Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.

Biochemistry. 1998 Nov 24;37(47):16465-71.

PMID:
9843412
10.

Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.

Ryazantseva M, Skobeleva K, Glushankova L, Kaznacheyeva E.

J Neurochem. 2016 Mar;136(5):1085-95. doi: 10.1111/jnc.13495. Epub 2016 Jan 11.

11.

Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease.

Honarnejad K, Jung CK, Lammich S, Arzberger T, Kretzschmar H, Herms J.

J Cell Mol Med. 2013 Feb;17(2):293-302. doi: 10.1111/jcmm.12008. Epub 2013 Feb 5.

12.

Enhanced ER Ca2+ store filling by overexpression of SERCA2b promotes IP3-evoked puffs.

Yamasaki-Mann M, Parker I.

Cell Calcium. 2011 Jul;50(1):36-41. doi: 10.1016/j.ceca.2011.04.008. Epub 2011 May 26.

13.

Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk.

Zampese E, Fasolato C, Kipanyula MJ, Bortolozzi M, Pozzan T, Pizzo P.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2777-82. doi: 10.1073/pnas.1100735108. Epub 2011 Feb 1.

14.

Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells.

Cook NL, Viola HM, Sharov VS, Hool LC, Schöneich C, Davies MJ.

Free Radic Biol Med. 2012 Mar 1;52(5):951-61. doi: 10.1016/j.freeradbiomed.2011.12.001. Epub 2011 Dec 23.

15.

Highly cooperative dependence of sarco/endoplasmic reticulum calcium ATPase SERCA2a pump activity on cytosolic calcium in living cells.

Satoh K, Matsu-Ura T, Enomoto M, Nakamura H, Michikawa T, Mikoshiba K.

J Biol Chem. 2011 Jun 10;286(23):20591-9. doi: 10.1074/jbc.M110.204685. Epub 2011 Apr 22.

16.
17.

Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell.

Johnson JS, Kono T, Tong X, Yamamoto WR, Zarain-Herzberg A, Merrins MJ, Satin LS, Gilon P, Evans-Molina C.

J Biol Chem. 2014 Nov 21;289(47):32798-810. doi: 10.1074/jbc.M114.575191. Epub 2014 Sep 30.

18.

Presenilin-1 holoprotein is an interacting partner of sarco endoplasmic reticulum calcium-ATPase and confers resistance to endoplasmic reticulum stress.

Jin H, Sanjo N, Uchihara T, Watabe K, St George-Hyslop P, Fraser PE, Mizusawa H.

J Alzheimers Dis. 2010;20(1):261-73. doi: 10.3233/JAD-2010-1360.

PMID:
20164584
20.

Uncoupling protein 3 (UCP3) modulates the activity of Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) by decreasing mitochondrial ATP production.

De Marchi U, Castelbou C, Demaurex N.

J Biol Chem. 2011 Sep 16;286(37):32533-41. doi: 10.1074/jbc.M110.216044. Epub 2011 Jul 20.

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