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Correlation between serotonin synthesis and 5-HT1A receptor binding in the living human brain: a combined alpha-[11C]MT and [18F]MPPF positron emission tomography study.

Frey BN, Rosa-Neto P, Lubarsky S, Diksic M.

Neuroimage. 2008 Aug 15;42(2):850-7. doi: 10.1016/j.neuroimage.2008.05.009. Epub 2008 May 17.


Association between triallelic polymorphism of the serotonin transporter and [18F]MPPF binding potential at 5-HT1A receptors in healthy subjects.

Lothe A, Boni C, Costes N, Gorwood P, Bouvard S, Le Bars D, Lavenne F, Ryvlin P.

Neuroimage. 2009 Aug 15;47(2):482-92. doi: 10.1016/j.neuroimage.2009.04.067. Epub 2009 May 3.


Marmoset Serotonin 5-HT1A Receptor Mapping with a Biased Agonist PET Probe 18F-F13714: Comparison with an Antagonist Tracer 18F-MPPF in Awake and Anesthetized States.

Yokoyama C, Mawatari A, Kawasaki A, Takeda C, Onoe K, Doi H, Newman-Tancredi A, Zimmer L, Onoe H.

Int J Neuropsychopharmacol. 2016 Dec 30;19(12). pii: pyw079. doi: 10.1093/ijnp/pyw079. Print 2016 Dec.


Serotonergic neurotransmission in the living human brain: a positron emission tomography study using [¹¹C]dasb and [¹¹C]WAY100635 in young healthy men.

Takano H, Ito H, Takahashi H, Arakawa R, Okumura M, Kodaka F, Otsuka T, Kato M, Suhara T.

Synapse. 2011 Jul;65(7):624-33. doi: 10.1002/syn.20883. Epub 2011 Jan 12.


Serotonin-1A receptor imaging in recurrent depression: replication and literature review.

Drevets WC, Thase ME, Moses-Kolko EL, Price J, Frank E, Kupfer DJ, Mathis C.

Nucl Med Biol. 2007 Oct;34(7):865-77. Review.


5-HT1A gene promoter polymorphism and [18F]MPPF binding potential in healthy subjects: a PET study.

Lothe A, Boni C, Costes N, Bouvard S, Gorwood P, Lavenne F, Alvarez M, Ryvlin P.

Behav Brain Funct. 2010 Jul 7;6:37. doi: 10.1186/1744-9081-6-37.


In vivo kinetics of [F-18]MEFWAY: a comparison with [C-11]WAY100635 and [F-18]MPPF in the nonhuman primate.

Wooten DW, Moraino JD, Hillmer AT, Engle JW, Dejesus OJ, Murali D, Barnhart TE, Nickles RJ, Davidson RJ, Schneider ML, Mukherjee J, Christian BT.

Synapse. 2011 Jul;65(7):592-600. doi: 10.1002/syn.20878. Epub 2010 Dec 8.


First-in-human evaluation of 18F-mefway, a PET radioligand specific to serotonin-1A receptors.

Hillmer AT, Wooten DW, Bajwa AK, Higgins AT, Lao PJ, Betthauser TJ, Barnhart TE, Rowley HA, Stone CK, Johnson SC, Mukherjee J, Christian BT.

J Nucl Med. 2014 Dec;55(12):1973-9. doi: 10.2967/jnumed.114.145151. Epub 2014 Nov 13.


Comorbidity between temporal lobe epilepsy and depression: a [18F]MPPF PET study.

Lothe A, Didelot A, Hammers A, Costes N, Saoud M, Gilliam F, Ryvlin P.

Brain. 2008 Oct;131(Pt 10):2765-82. doi: 10.1093/brain/awn194. Epub 2008 Sep 2.


Stability of alpha-[11C]methyl-L-tryptophan brain trapping in healthy male volunteers.

Rosa-Neto P, Diksic M, Leyton M, Mzengeza S, Benkelfat C.

Eur J Nucl Med Mol Imaging. 2005 Oct;32(10):1199-204. Epub 2005 Jun 10.


Synthesis and biologic evaluation of a novel serotonin 5-HT1A receptor radioligand, 18F-labeled mefway, in rodents and imaging by PET in a nonhuman primate.

Saigal N, Pichika R, Easwaramoorthy B, Collins D, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J.

J Nucl Med. 2006 Oct;47(10):1697-706.


Global decrease of serotonin-1A receptor binding after electroconvulsive therapy in major depression measured by PET.

Lanzenberger R, Baldinger P, Hahn A, Ungersboeck J, Mitterhauser M, Winkler D, Micskei Z, Stein P, Karanikas G, Wadsak W, Kasper S, Frey R.

Mol Psychiatry. 2013 Jan;18(1):93-100. doi: 10.1038/mp.2012.93. Epub 2012 Jul 3.


Uptake and binding of the serotonin 5-HT1A antagonist [18F]-MPPF in brain of rats: effects of the novel P-glycoprotein inhibitor tariquidar.

la Fougère C, Böning G, Bartmann H, Wängler B, Nowak S, Just T, Wagner E, Winter P, Rominger A, Förster S, Gildehaus FJ, Rosa-Neto P, Minuzzi L, Bartenstein P, Potschka H, Cumming P.

Neuroimage. 2010 Jan 15;49(2):1406-15. doi: 10.1016/j.neuroimage.2009.09.048. Epub 2009 Sep 28.


Hypothalamic serotonin-1A receptor binding measured by PET predicts the plasma level of dehydroepiandrosterone sulfate in healthy women.

Moser U, Wadsak W, Spindelegger C, Mitterhauser M, Mien LK, Bieglmayer C, Kletter K, Kasper S, Lanzenberger R.

Neurosci Lett. 2010 Jun 7;476(3):161-5. doi: 10.1016/j.neulet.2010.04.020. Epub 2010 Apr 22.


Genetic variation in brain-derived neurotrophic factor val66met allele is associated with altered serotonin-1A receptor binding in human brain.

Lan MJ, Ogden RT, Huang YY, Oquendo MA, Sullivan GM, Miller J, Milak M, Mann JJ, Parsey RV.

Neuroimage. 2014 Jul 1;94:33-39. doi: 10.1016/j.neuroimage.2014.02.027. Epub 2014 Mar 5.


Positron emission tomography quantification of serotonin-1A receptor binding in medication-free bipolar depression.

Sullivan GM, Ogden RT, Oquendo MA, Kumar JS, Simpson N, Huang YY, Mann JJ, Parsey RV.

Biol Psychiatry. 2009 Aug 1;66(3):223-30. doi: 10.1016/j.biopsych.2009.01.028. Epub 2009 Mar 17.


Effect of fenfluramine-induced increases in serotonin release on [18F]MPPF binding: a continuous infusion PET study in conscious monkeys.

Udo de Haes JI, Harada N, Elsinga PH, Maguire RP, Tsukada H.

Synapse. 2006 Jan;59(1):18-26.


A distinct [18F]MPPF PET profile in amnestic mild cognitive impairment compared to mild Alzheimer's disease.

Truchot L, Costes N, Zimmer L, Laurent B, Le Bars D, Thomas-Antérion C, Mercier B, Hermier M, Vighetto A, Krolak-Salmon P.

Neuroimage. 2008 Apr 15;40(3):1251-6. doi: 10.1016/j.neuroimage.2008.01.030. Epub 2008 Feb 1.


Decreased [18F]MPPF binding potential in the dorsal raphe nucleus after a single oral dose of fluoxetine: a positron-emission tomography study in healthy volunteers.

Sibon I, Benkelfat C, Gravel P, Aznavour N, Costes N, Mzengeza S, Booij L, Baker G, Soucy JP, Zimmer L, Descarries L.

Biol Psychiatry. 2008 Jun 15;63(12):1135-40. doi: 10.1016/j.biopsych.2007.11.016. Epub 2008 Jan 14.


Lateralization of the serotonin-1A receptor distribution in language areas revealed by PET.

Fink M, Wadsak W, Savli M, Stein P, Moser U, Hahn A, Mien LK, Kletter K, Mitterhauser M, Kasper S, Lanzenberger R.

Neuroimage. 2009 Apr 1;45(2):598-605. doi: 10.1016/j.neuroimage.2008.11.033. Epub 2008 Dec 9.


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