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Items: 1 to 20 of 487

1.

Interaction of scaffolding adaptor protein Gab1 with tyrosine phosphatase SHP2 negatively regulates IGF-I-dependent myogenic differentiation via the ERK1/2 signaling pathway.

Koyama T, Nakaoka Y, Fujio Y, Hirota H, Nishida K, Sugiyama S, Okamoto K, Yamauchi-Takihara K, Yoshimura M, Mochizuki S, Hori M, Hirano T, Mochizuki N.

J Biol Chem. 2008 Aug 29;283(35):24234-44. doi: 10.1074/jbc.M803907200. Epub 2008 Jun 23.

2.

EphrinA/EphA signal facilitates insulin-like growth factor-I-induced myogenic differentiation through suppression of the Ras/extracellular signal-regulated kinase 1/2 cascade in myoblast cell lines.

Minami M, Koyama T, Wakayama Y, Fukuhara S, Mochizuki N.

Mol Biol Cell. 2011 Sep;22(18):3508-19. doi: 10.1091/mbc.E11-03-0183. Epub 2011 Jul 27.

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Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes.

Nakaoka Y, Nishida K, Fujio Y, Izumi M, Terai K, Oshima Y, Sugiyama S, Matsuda S, Koyasu S, Yamauchi-Takihara K, Hirano T, Kawase I, Hirota H.

Circ Res. 2003 Aug 8;93(3):221-9. Epub 2003 Jul 10.

6.

Extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase pathway is involved in inhibition of myogenic differentiation of myoblasts by hypoxia.

Li X, Wang X, Zhang P, Zhu L, Zhao T, Liu S, Wu Y, Chen X, Fan M.

Exp Physiol. 2012 Feb;97(2):257-64. doi: 10.1113/expphysiol.2011.061382. Epub 2011 Oct 14.

7.

ERK2 is required for efficient terminal differentiation of skeletal myoblasts.

Li J, Johnson SE.

Biochem Biophys Res Commun. 2006 Jul 14;345(4):1425-33. Epub 2006 May 16.

PMID:
16729973
8.

Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylation.

Marino JS, Hinds TD Jr, Potter RA, Ondrus E, Onion JL, Dowling A, McLoughlin TJ, Sanchez ER, Hill JW.

BMC Cell Biol. 2013 Sep 21;14:39. doi: 10.1186/1471-2121-14-39.

10.

Gab1 transduces PI3K-mediated erythropoietin signals to the Erk pathway and regulates erythropoietin-dependent proliferation and survival of erythroid cells.

Fukumoto T, Kubota Y, Kitanaka A, Yamaoka G, Ohara-Waki F, Imataki O, Ohnishi H, Ishida T, Tanaka T.

Cell Signal. 2009 Dec;21(12):1775-83. doi: 10.1016/j.cellsig.2009.07.013. Epub 2009 Aug 6.

PMID:
19665053
11.

Role of SHP-2 in fibroblast growth factor receptor-mediated suppression of myogenesis in C2C12 myoblasts.

Kontaridis MI, Liu X, Zhang L, Bennett AM.

Mol Cell Biol. 2002 Jun;22(11):3875-91.

13.

The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells.

El-Shewy HM, Lee MH, Obeid LM, Jaffa AA, Luttrell LM.

J Biol Chem. 2007 Sep 7;282(36):26150-7. Epub 2007 Jul 9.

15.

Constitutive expression of insulin receptor substrate (IRS)-1 inhibits myogenic differentiation through nuclear exclusion of Foxo1 in L6 myoblasts.

Hakuno F, Yamauchi Y, Kaneko G, Yoneyama Y, Nakae J, Chida K, Kadowaki T, Yamanouchi K, Nishihara M, Takahashi S.

PLoS One. 2011;6(10):e25655. doi: 10.1371/journal.pone.0025655. Epub 2011 Oct 3.

16.

Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature.

De Rocca Serra-Nédélec A, Edouard T, Tréguer K, Tajan M, Araki T, Dance M, Mus M, Montagner A, Tauber M, Salles JP, Valet P, Neel BG, Raynal P, Yart A.

Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4257-62. doi: 10.1073/pnas.1119803109. Epub 2012 Feb 27.

17.

Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.

Zhang SQ, Tsiaras WG, Araki T, Wen G, Minichiello L, Klein R, Neel BG.

Mol Cell Biol. 2002 Jun;22(12):4062-72.

18.

A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.

Yart A, Laffargue M, Mayeux P, Chretien S, Peres C, Tonks N, Roche S, Payrastre B, Chap H, Raynal P.

J Biol Chem. 2001 Mar 23;276(12):8856-64. Epub 2000 Dec 27.

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