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Items: 1 to 20 of 56

1.

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds.

Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, Chen AE, Melton DA.

Nat Biotechnol. 2008 Jul;26(7):795-7. doi: 10.1038/nbt1418. Epub 2008 Jun 22.

PMID:
18568017
2.

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.

Huangfu D, Osafune K, Maehr R, Guo W, Eijkelenboom A, Chen S, Muhlestein W, Melton DA.

Nat Biotechnol. 2008 Nov;26(11):1269-75. doi: 10.1038/nbt.1502. Epub 2008 Oct 12.

PMID:
18849973
3.
4.

Valproic acid and all trans retinoic acid differentially induce megakaryopoiesis and platelet-like particle formation from the megakaryoblastic cell line MEG-01.

Schweinfurth N, Hohmann S, Deuschle M, Lederbogen F, Schloss P.

Platelets. 2010;21(8):648-57. doi: 10.3109/09537104.2010.513748. Epub 2010 Oct 13.

PMID:
20942599
5.

Induction of hepatic differentiation of mouse bone marrow stromal stem cells by the histone deacetylase inhibitor VPA.

Chen Y, Pan RL, Zhang XL, Shao JZ, Xiang LX, Dong XJ, Zhang GR.

J Cell Mol Med. 2009 Aug;13(8B):2582-92. doi: 10.1111/j.1582-4934.2008.00471.x.

6.

A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells.

Lee J, Xia Y, Son MY, Jin G, Seol B, Kim MJ, Son MJ, Do M, Lee M, Kim D, Lee K, Cho YS.

Angew Chem Int Ed Engl. 2012 Dec 7;51(50):12509-13. doi: 10.1002/anie.201206691. Epub 2012 Nov 4.

PMID:
23125037
7.

Histone deacetylase inhibitors decrease proliferation potential and multilineage differentiation capability of human mesenchymal stem cells.

Lee S, Park JR, Seo MS, Roh KH, Park SB, Hwang JW, Sun B, Seo K, Lee YS, Kang SK, Jung JW, Kang KS.

Cell Prolif. 2009 Dec;42(6):711-20. doi: 10.1111/j.1365-2184.2009.00633.x. Epub 2009 Aug 17.

PMID:
19689470
8.

Valproic acid enhances Oct4 promoter activity in myogenic cells.

Teng HF, Kuo YL, Loo MR, Li CL, Chu TW, Suo H, Liu HS, Lin KH, Chen SL.

J Cell Biochem. 2010 Jul 1;110(4):995-1004. doi: 10.1002/jcb.22613.

PMID:
20564199
9.

Inhibition of class IIb histone deacetylase significantly improves cloning efficiency in mice.

Ono T, Li C, Mizutani E, Terashita Y, Yamagata K, Wakayama T.

Biol Reprod. 2010 Dec;83(6):929-37. doi: 10.1095/biolreprod.110.085282. Epub 2010 Aug 4.

PMID:
20686182
10.

Enhanced reprogramming of Xist by induced upregulation of Tsix and Dnmt3a.

Do JT, Han DW, Gentile L, Sobek-Klocke I, Stehling M, Schöler HR.

Stem Cells. 2008 Nov;26(11):2821-31. doi: 10.1634/stemcells.2008-0482. Epub 2008 Aug 28.

11.

Histone deacetylase inhibitor valproic acid as a small molecule inducer to direct the differentiation of pluripotent stem cells.

Chen J, Lacroix N, Li Q.

Methods Mol Biol. 2013;977:359-63. doi: 10.1007/978-1-62703-284-1_29.

PMID:
23436377
12.
13.

Histone deacetylase inhibitor valproic acid promotes the induction of pluripotency in mouse fibroblasts by suppressing reprogramming-induced senescence stress.

Zhai Y, Chen X, Yu D, Li T, Cui J, Wang G, Hu JF, Li W.

Exp Cell Res. 2015 Sep 10;337(1):61-7. doi: 10.1016/j.yexcr.2015.06.003. Epub 2015 Jun 22.

PMID:
26112217
14.

Anti-leukemic activity of valproic acid and imatinib mesylate on human Ph+ ALL and CML cells in vitro.

Kircher B, Schumacher P, Petzer A, Hoflehner E, Haun M, Wolf AM, Nachbaur D, Gastl G.

Eur J Haematol. 2009 Jul;83(1):48-56. doi: 10.1111/j.1600-0609.2009.01242.x. Epub 2009 Feb 17.

PMID:
19226363
15.

Valproic Acid Enhances iPSC Induction From Human Bone Marrow-Derived Cells Through the Suppression of Reprogramming-Induced Senescence.

Chen X, Zhai Y, Yu D, Cui J, Hu JF, Li W.

J Cell Physiol. 2016 Aug;231(8):1719-27. doi: 10.1002/jcp.25270. Epub 2015 Dec 28.

PMID:
26620855
16.

Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors.

Haumaitre C, Lenoir O, Scharfmann R.

Mol Cell Biol. 2008 Oct;28(20):6373-83. doi: 10.1128/MCB.00413-08. Epub 2008 Aug 18.

17.

Reprogramming of murine and human somatic cells using a single polycistronic vector.

Carey BW, Markoulaki S, Hanna J, Saha K, Gao Q, Mitalipova M, Jaenisch R.

Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):157-62. doi: 10.1073/pnas.0811426106. Epub 2008 Dec 24. Erratum in: Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5449. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11818.

18.

Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells.

Kondo Y, Iwao T, Yoshihashi S, Mimori K, Ogihara R, Nagata K, Kurose K, Saito M, Niwa T, Suzuki T, Miyata N, Ohmori S, Nakamura K, Matsunaga T.

PLoS One. 2014 Aug 1;9(8):e104010. doi: 10.1371/journal.pone.0104010. eCollection 2014.

19.

In vivo anti-myeloma activity and modulation of gene expression profile induced by valproic acid, a histone deacetylase inhibitor.

Neri P, Tagliaferri P, Di Martino MT, Calimeri T, Amodio N, Bulotta A, Ventura M, Eramo PO, Viscomi C, Arbitrio M, Rossi M, Caraglia M, Munshi NC, Anderson KC, Tassone P.

Br J Haematol. 2008 Nov;143(4):520-31. doi: 10.1111/j.1365-2141.2008.07387.x.

PMID:
18986388
20.

Valproic acid enhances the engraftability of human umbilical cord blood hematopoietic stem cells expanded under serum-free conditions.

Seet LF, Teng E, Lai YS, Laning J, Kraus M, Wnendt S, Merchav S, Chan SL.

Eur J Haematol. 2009 Feb;82(2):124-32. doi: 10.1111/j.1600-0609.2008.01169.x. Epub 2008 Nov 10.

PMID:
19067743

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