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Items: 1 to 20 of 116

1.

Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt.

Chan AY, Dolinsky VW, Soltys CL, Viollet B, Baksh S, Light PE, Dyck JR.

J Biol Chem. 2008 Aug 29;283(35):24194-201. doi: 10.1074/jbc.M802869200. Epub 2008 Jun 18.

2.

Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy.

Li HL, Yin R, Chen D, Liu D, Wang D, Yang Q, Dong YG.

J Cell Biochem. 2007 Apr 1;100(5):1086-99.

PMID:
17266062
3.

Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte.

Chan AY, Soltys CL, Young ME, Proud CG, Dyck JR.

J Biol Chem. 2004 Jul 30;279(31):32771-9. Epub 2004 May 24.

4.

Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1.

Dolinsky VW, Chan AY, Robillard Frayne I, Light PE, Des Rosiers C, Dyck JR.

Circulation. 2009 Mar 31;119(12):1643-52. doi: 10.1161/CIRCULATIONAHA.108.787440. Epub 2009 Mar 16.

PMID:
19289642
5.

Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophy.

Noga AA, Soltys CL, Barr AJ, Kovacic S, Lopaschuk GD, Dyck JR.

Am J Physiol Heart Circ Physiol. 2007 Mar;292(3):H1460-9. Epub 2006 Nov 10.

7.

Oxidative stress induces GLUT4 translocation by activation of PI3-K/Akt and dual AMPK kinase in cardiac myocytes.

Horie T, Ono K, Nagao K, Nishi H, Kinoshita M, Kawamura T, Wada H, Shimatsu A, Kita T, Hasegawa K.

J Cell Physiol. 2008 Jun;215(3):733-42. doi: 10.1002/jcp.21353.

PMID:
18163380
8.

Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake.

Ginion A, Auquier J, Benton CR, Mouton C, Vanoverschelde JL, Hue L, Horman S, Beauloye C, Bertrand L.

Am J Physiol Heart Circ Physiol. 2011 Aug;301(2):H469-77. doi: 10.1152/ajpheart.00986.2010. Epub 2011 May 20.

9.

Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart.

Kovacic S, Soltys CL, Barr AJ, Shiojima I, Walsh K, Dyck JR.

J Biol Chem. 2003 Oct 10;278(41):39422-7. Epub 2003 Jul 29. Erratum in: J Biol Chem. 2004 Jan 16;279(3):2332.

10.

Resveratrol prevents pathological but not physiological cardiac hypertrophy.

Dolinsky VW, Soltys CL, Rogan KJ, Chan AY, Nagendran J, Wang S, Dyck JR.

J Mol Med (Berl). 2015 Apr;93(4):413-25. doi: 10.1007/s00109-014-1220-8. Epub 2014 Nov 15.

PMID:
25394677
12.

Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase.

Park CE, Kim MJ, Lee JH, Min BI, Bae H, Choe W, Kim SS, Ha J.

Exp Mol Med. 2007 Apr 30;39(2):222-9.

PMID:
17464184
13.

Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR.

Cai Y, Wang Q, Ling Z, Pipeleers D, McDermott P, Pende M, Heimberg H, Van de Casteele M.

Biochem Pharmacol. 2008 May 15;75(10):1981-93. doi: 10.1016/j.bcp.2008.02.019. Epub 2008 Feb 26.

PMID:
18377870
14.

AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol.

Zarrinpashneh E, Beauloye C, Ginion A, Pouleur AC, Havaux X, Hue L, Viollet B, Vanoverschelde JL, Bertrand L.

Biochem Biophys Res Commun. 2008 Nov 28;376(4):677-81. doi: 10.1016/j.bbrc.2008.09.057. Epub 2008 Sep 21.

PMID:
18812163
15.

The AMPK gamma1 R70Q mutant regulates multiple metabolic and growth pathways in neonatal cardiac myocytes.

Folmes KD, Witters LA, Allard MF, Young ME, Dyck JR.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3456-64. Epub 2007 Sep 28.

16.

Resveratrol reverses remodeling in hearts with large, old myocardial infarctions through enhanced autophagy-activating AMP kinase pathway.

Kanamori H, Takemura G, Goto K, Tsujimoto A, Ogino A, Takeyama T, Kawaguchi T, Watanabe T, Morishita K, Kawasaki M, Mikami A, Fujiwara T, Fujiwara H, Seishima M, Minatoguchi S.

Am J Pathol. 2013 Mar;182(3):701-13. doi: 10.1016/j.ajpath.2012.11.009. Epub 2012 Dec 28.

PMID:
23274061
17.
18.

Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation.

Chung E, Yeung F, Leinwand LA.

J Appl Physiol (1985). 2012 May;112(9):1564-75. doi: 10.1152/japplphysiol.00027.2012. Epub 2012 Feb 16.

19.

AMP activated protein kinase-alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice.

Zhang P, Hu X, Xu X, Fassett J, Zhu G, Viollet B, Xu W, Wiczer B, Bernlohr DA, Bache RJ, Chen Y.

Hypertension. 2008 Nov;52(5):918-24. doi: 10.1161/HYPERTENSIONAHA.108.114702. Epub 2008 Oct 6.

20.

Pioglitazone attenuates cardiac hypertrophy in rats with salt-sensitive hypertension: role of activation of AMP-activated protein kinase and inhibition of Akt.

Kato MF, Shibata R, Obata K, Miyachi M, Yazawa H, Tsuboi K, Yamada T, Nishizawa T, Noda A, Cheng XW, Murate T, Koike Y, Murohara T, Yokota M, Nagata K.

J Hypertens. 2008 Aug;26(8):1669-76. doi: 10.1097/HJH.0b013e328302f0f7.

PMID:
18622247

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