Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 141

1.

Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis.

Sohn SJ, Lewis GM, Winoto A.

EMBO J. 2008 Jul 9;27(13):1896-906. doi: 10.1038/emboj.2008.114. Epub 2008 Jun 12.

2.

Requirement of the MEK5-ERK5 pathway for neural differentiation in Xenopus embryonic development.

Nishimoto S, Kusakabe M, Nishida E.

EMBO Rep. 2005 Nov;6(11):1064-9. Epub 2005 Sep 23.

3.

ERK5 is involved in TCR-induced apoptosis through the modification of Nur77.

Fujii Y, Matsuda S, Takayama G, Koyasu S.

Genes Cells. 2008 May;13(5):411-9. doi: 10.1111/j.1365-2443.2008.01177.x.

4.

Identification of pharmacological inhibitors of the MEK5/ERK5 pathway.

Tatake RJ, O'Neill MM, Kennedy CA, Wayne AL, Jakes S, Wu D, Kugler SZ Jr, Kashem MA, Kaplita P, Snow RJ.

Biochem Biophys Res Commun. 2008 Dec 5;377(1):120-5. doi: 10.1016/j.bbrc.2008.09.087. Epub 2008 Oct 1.

PMID:
18834865
6.

PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway.

Nakamura K, Johnson GL.

J Biol Chem. 2003 Sep 26;278(39):36989-92. Epub 2003 Aug 11.

7.

Regulation of cellular functions by the ERK5 signalling pathway.

Wang X, Tournier C.

Cell Signal. 2006 Jun;18(6):753-60. Epub 2006 Jan 6. Review.

PMID:
16376520
8.

MAPK signalling: ERK5 versus ERK1/2.

Nishimoto S, Nishida E.

EMBO Rep. 2006 Aug;7(8):782-6. Review.

9.

Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway.

Li Z, Li J, Mo B, Hu C, Liu H, Qi H, Wang X, Xu J.

Toxicol In Vitro. 2008 Oct;22(7):1749-53. doi: 10.1016/j.tiv.2008.08.001. Epub 2008 Aug 12.

PMID:
18761399
10.

G alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR).

García-Hoz C, Sánchez-Fernández G, Díaz-Meco MT, Moscat J, Mayor F, Ribas C.

J Biol Chem. 2010 Apr 30;285(18):13480-9. doi: 10.1074/jbc.M109.098699. Epub 2010 Mar 3.

11.

MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway.

Sun W, Kesavan K, Schaefer BC, Garrington TP, Ware M, Johnson NL, Gelfand EW, Johnson GL.

J Biol Chem. 2001 Feb 16;276(7):5093-100. Epub 2000 Nov 9.

12.

The signaling pathway leading to extracellular signal-regulated kinase 5 (ERK5) activation via G-proteins and ERK5-dependent neurotrophic effects.

Obara Y, Nakahata N.

Mol Pharmacol. 2010 Jan;77(1):10-6. doi: 10.1124/mol.109.060236. Epub 2009 Oct 26. Review.

PMID:
19858097
13.

MEK5/ERK5 signaling modulates endothelial cell migration and focal contact turnover.

Spiering D, Schmolke M, Ohnesorge N, Schmidt M, Goebeler M, Wegener J, Wixler V, Ludwig S.

J Biol Chem. 2009 Sep 11;284(37):24972-80. doi: 10.1074/jbc.M109.042911. Epub 2009 Jul 15.

14.

PB1 domain-dependent signaling complex is required for extracellular signal-regulated kinase 5 activation.

Nakamura K, Uhlik MT, Johnson NL, Hahn KM, Johnson GL.

Mol Cell Biol. 2006 Mar;26(6):2065-79.

15.

YAP promotes myogenic differentiation via the MEK5-ERK5 pathway.

Chen TH, Chen CY, Wen HC, Chang CC, Wang HD, Chuu CP, Chang CH.

FASEB J. 2017 Jul;31(7):2963-2972. doi: 10.1096/fj.201601090R. Epub 2017 Mar 29.

PMID:
28356344
16.

Characterization of the MEK5-ERK5 module in human neutrophils and its relationship to ERK1/ERK2 in the chemotactic response.

Hii CS, Anson DS, Costabile M, Mukaro V, Dunning K, Ferrante A.

J Biol Chem. 2004 Nov 26;279(48):49825-34. Epub 2004 Sep 20.

17.

Protein phosphatase subunit G5PR that regulates the JNK-mediated apoptosis signal is essential for the survival of CD4 and CD8 double-positive thymocytes.

Xing Y, Wang X, Igarashi H, Kawamoto H, Sakaguchi N.

Mol Immunol. 2008 Apr;45(7):2028-37. Epub 2007 Nov 19.

PMID:
18022237
18.

Identification of benzimidazole-based inhibitors of the mitogen activated kinase-5 signaling pathway.

Flaherty PT, Chopra I, Jain P, Yi S, Allen E, Cavanaugh J.

Bioorg Med Chem Lett. 2010 May 1;20(9):2892-6. doi: 10.1016/j.bmcl.2010.03.033. Epub 2010 Mar 10.

PMID:
20382528
19.

The MEK5/ERK5 signalling pathway in cancer: a promising novel therapeutic target.

Simões AE, Rodrigues CM, Borralho PM.

Drug Discov Today. 2016 Oct;21(10):1654-1663. doi: 10.1016/j.drudis.2016.06.010. Epub 2016 Jun 16. Review.

PMID:
27320690
20.

Multisite phosphorylation of Erk5 in mitosis.

Díaz-Rodríguez E, Pandiella A.

J Cell Sci. 2010 Sep 15;123(Pt 18):3146-56. doi: 10.1242/jcs.070516. Epub 2010 Aug 24.

Supplemental Content

Support Center