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Items: 1 to 20 of 191

1.

Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in tuberculosis patients.

Fukino K, Sasaki Y, Hirai S, Nakamura T, Hashimoto M, Yamagishi F, Ueno K.

J Toxicol Sci. 2008 May;33(2):187-95. Erratum in: J Toxicol Sci. 2008 Dec;33(5):667.

2.

Association of isoniazid-metabolizing enzyme genotypes and isoniazid-induced hepatotoxicity in tuberculosis patients.

Sotsuka T, Sasaki Y, Hirai S, Yamagishi F, Ueno K.

In Vivo. 2011 Sep-Oct;25(5):803-12.

PMID:
21753138
3.

Association of NAT2, GST and CYP2E1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity.

Singla N, Gupta D, Birbian N, Singh J.

Tuberculosis (Edinb). 2014 May;94(3):293-8. doi: 10.1016/j.tube.2014.02.003. Epub 2014 Feb 15.

PMID:
24637014
4.

Study of NAT2 gene polymorphisms in an Indian population: association with plasma isoniazid concentration in a cohort of tuberculosis patients.

Singh N, Dubey S, Chinnaraj S, Golani A, Maitra A.

Mol Diagn Ther. 2009;13(1):49-58. doi: 10.2165/01250444-200913010-00007.

PMID:
19351215
5.

The influence of NAT2 genotypes on the plasma concentration of isoniazid and acetylisoniazid in Chinese pulmonary tuberculosis patients.

Chen B, Li JH, Xu YM, Wang J, Cao XM.

Clin Chim Acta. 2006 Mar;365(1-2):104-8. Epub 2005 Sep 21.

PMID:
16182272
7.

The influence of dose and N-acetyltransferase-2 (NAT2) genotype and phenotype on the pharmacokinetics and pharmacodynamics of isoniazid.

Donald PR, Parkin DP, Seifart HI, Schaaf HS, van Helden PD, Werely CJ, Sirgel FA, Venter A, Maritz JS.

Eur J Clin Pharmacol. 2007 Jul;63(7):633-9. Epub 2007 May 16.

PMID:
17505821
8.

Genetic interaction between NAT2, GSTM1, GSTT1, CYP2E1, and environmental factors is associated with adverse reactions to anti-tuberculosis drugs.

Costa GN, Magno LA, Santana CV, Konstantinovas C, Saito ST, Machado M, Di Pietro G, Bastos-Rodrigues L, Miranda DM, De Marco LA, Romano-Silva MA, Rios-Santos F.

Mol Diagn Ther. 2012 Aug 1;16(4):241-50. doi: 10.2165/11634480-000000000-00000.

PMID:
22788240
9.

N-Acetyltransferase2 genotype correlated with isoniazid acetylation in Japanese tuberculous patients.

Kita T, Tanigawara Y, Chikazawa S, Hatanaka H, Sakaeda T, Komada F, Iwakawa S, Okumura K.

Biol Pharm Bull. 2001 May;24(5):544-9.

10.

Glutathione S-transferase and N-acetyltransferase genotypes and asbestos-associated pulmonary disorders.

Hirvonen A, Saarikoski ST, Linnainmaa K, Koskinen K, Husgafvel-Pursiainen K, Mattson K, Vainio H.

J Natl Cancer Inst. 1996 Dec 18;88(24):1853-6.

PMID:
8961976
11.

Glutathione S-transferase (GST) M1, T1 and N-acetyltransferase 2 (NAT2) polymorphisms and urothelial cancer risk with tobacco smoking.

Tsukino H, Nakao H, Kuroda Y, Imai H, Inatomi H, Osada Y, Katoh T.

Eur J Cancer Prev. 2004 Dec;13(6):509-14.

PMID:
15548945
12.

Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients.

Teixeira RL, Morato RG, Cabello PH, Muniz LM, Moreira Ada S, Kritski AL, Mello FC, Suffys PN, Miranda AB, Santos AR.

Mem Inst Oswaldo Cruz. 2011 Sep;106(6):716-24.

13.

[Cytochrome P450 and NAT2 polymorphisms and drug metabolism in DOTS].

Castillejos-López Mde J, García-Sancho MC, Quiñones-Falconi F, Pérez-Padilla JR.

Rev Invest Clin. 2008 Jan-Feb;60(1):47-57. Review. Spanish.

PMID:
18589587
14.

N-acetyltransferase 2, cytochrome P4502E1 and glutathione S-transferase genotypes in antitubercular treatment-induced hepatotoxicity in North Indians.

Rana SV, Sharma SK, Ola RP, Kamboj JK, Malik A, Morya RK, Sinha SK.

J Clin Pharm Ther. 2014 Feb;39(1):91-6. doi: 10.1111/jcpt.12105. Epub 2013 Nov 5.

PMID:
24188272
15.

A proposal for an individualized pharmacogenetic-guided isoniazid dosage regimen for patients with tuberculosis.

Jung JA, Kim TE, Lee H, Jeong BH, Park HY, Jeon K, Kwon OJ, Ko JW, Choi R, Woo HI, Koh WJ, Lee SY.

Drug Des Devel Ther. 2015 Sep 30;9:5433-8. doi: 10.2147/DDDT.S87131. eCollection 2015.

16.

Relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver enzymes in Brazilian individuals under anti-tuberculosis drug therapy.

Forestiero FJ, Cecon L, Hirata MH, de Melo FF, Cardoso RF, Cerda A, Hirata RD.

Clin Chim Acta. 2013 Jan 16;415:215-9. doi: 10.1016/j.cca.2012.10.030. Epub 2012 Oct 22.

17.

The incidence of liver injury in Uyghur patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, cyp2e1, gstm1 and gstt1.

Xiang Y, Ma L, Wu W, Liu W, Li Y, Zhu X, Wang Q, Ma J, Cao M, Wang Q, Yao X, Yang L, Wubuli A, Merle C, Milligan P, Mao Y, Gu J, Xin X.

PLoS One. 2014 Jan 23;9(1):e85905. doi: 10.1371/journal.pone.0085905. eCollection 2014.

18.

Dose-escalation study of isoniazid in healthy volunteers with the rapid acetylator genotype of arylamine N-acetyltransferase 2.

Kubota R, Ohno M, Hasunuma T, Iijima H, Azuma J.

Eur J Clin Pharmacol. 2007 Oct;63(10):927-33. Epub 2007 Jul 31.

PMID:
17665185
19.

N-acetyltransferase-2, glutathione S-transferase M1, alcohol dehydrogenase, and cytochrome P450IIE1 genotypes in alcoholic liver cirrhosis: a case-control study.

Rodrigo L, Alvarez V, Rodriguez M, Pérez R, Alvarez R, Coto E.

Scand J Gastroenterol. 1999 Mar;34(3):303-7.

PMID:
10232877
20.

Correlation of N-acetyltransferase 2 genotype with isoniazid acetylation in Polish tuberculosis patients.

Zabost A, Brzezińska S, Kozińska M, Błachnio M, Jagodziński J, Zwolska Z, Augustynowicz-Kopeć E.

Biomed Res Int. 2013;2013:853602. doi: 10.1155/2013/853602. Epub 2013 Dec 7.

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