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Items: 1 to 20 of 131

1.

Titin isoform switching is a major cardiac adaptive response in hibernating grizzly bears.

Nelson OL, Robbins CT, Wu Y, Granzier H.

Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H366-71. doi: 10.1152/ajpheart.00234.2008. Epub 2008 May 23.

2.

Cardiac function adaptations in hibernating grizzly bears (Ursus arctos horribilis).

Nelson OL, Robbins CT.

J Comp Physiol B. 2010 Mar;180(3):465-73. doi: 10.1007/s00360-009-0421-x. Epub 2009 Nov 26.

PMID:
19940994
3.
4.

Seasonal changes in isoform composition of giant proteins of thick and thin filaments and titin (connectin) phosphorylation level in striated muscles of bears (Ursidae, Mammalia).

Salmov NN, Vikhlyantsev IM, Ulanova AD, Gritsyna YV, Bobylev AG, Saveljev AP, Makariushchenko VV, Maksudov GY, Podlubnaya ZA.

Biochemistry (Mosc). 2015 Mar;80(3):343-55. doi: 10.1134/S0006297915030098.

PMID:
25761688
5.

Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy.

Nagueh SF, Shah G, Wu Y, Torre-Amione G, King NM, Lahmers S, Witt CC, Becker K, Labeit S, Granzier HL.

Circulation. 2004 Jul 13;110(2):155-62. Epub 2004 Jul 6.

6.

Evaluation of cardiac function in active and hibernating grizzly bears.

Nelson OL, McEwen MM, Robbins CT, Felicetti L, Christensen WF.

J Am Vet Med Assoc. 2003 Oct 15;223(8):1170-5.

PMID:
14584750
7.

Titin isoform switch in ischemic human heart disease.

Neagoe C, Kulke M, del Monte F, Gwathmey JK, de Tombe PP, Hajjar RJ, Linke WA.

Circulation. 2002 Sep 10;106(11):1333-41.

8.

Low cardiac output as physiological phenomenon in hibernating, free-ranging Scandinavian brown bears (Ursus arctos) - an observational study.

Jørgensen PG, Arnemo J, Swenson JE, Jensen JS, Galatius S, Frøbert O.

Cardiovasc Ultrasound. 2014 Sep 16;12:36. doi: 10.1186/1476-7120-12-36.

9.

Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodeling.

Hutchinson KR, Saripalli C, Chung CS, Granzier H.

J Mol Cell Cardiol. 2015 Feb;79:104-14. doi: 10.1016/j.yjmcc.2014.10.020. Epub 2014 Nov 8.

11.

Plasticity of cardiac titin/connectin in heart development.

Opitz CA, Linke WA.

J Muscle Res Cell Motil. 2005;26(6-8):333-42.

PMID:
16465471
12.

Cardiovascular function in large to small hibernators: bears to ground squirrels.

Nelson OL, Robbins CT.

J Comp Physiol B. 2015 Apr;185(3):265-79. doi: 10.1007/s00360-014-0881-5. Epub 2014 Dec 27. Review.

PMID:
25542162
13.

Titin isoform expression in aortic stenosis.

Williams L, Howell N, Pagano D, Andreka P, Vertesaljai M, Pecor T, Frenneaux M, Granzier H.

Clin Sci (Lond). 2009 Aug 14;117(6):237-42. doi: 10.1042/CS20080248.

14.

Grizzly bears (Ursus arctos horribilis) and black bears (Ursus americanus) prevent trabecular bone loss during disuse (hibernation).

McGee-Lawrence ME, Wojda SJ, Barlow LN, Drummer TD, Castillo AB, Kennedy O, Condon KW, Auger J, Black HL, Nelson OL, Robbins CT, Donahue SW.

Bone. 2009 Dec;45(6):1186-91. doi: 10.1016/j.bone.2009.08.011. Epub 2009 Aug 21.

15.

Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium.

Borbély A, Falcao-Pires I, van Heerebeek L, Hamdani N, Edes I, Gavina C, Leite-Moreira AF, Bronzwaer JG, Papp Z, van der Velden J, Stienen GJ, Paulus WJ.

Circ Res. 2009 Mar 27;104(6):780-6. doi: 10.1161/CIRCRESAHA.108.193326. Epub 2009 Jan 29.

16.

Hibernation-associated changes in persistent organic pollutant (POP) levels and patterns in British Columbia grizzly bears (ursus arctos horribilis).

Christensen JR, MacDuffee M, Yunker MB, Ross PS.

Environ Sci Technol. 2007 Mar 15;41(6):1834-40.

PMID:
17410772
17.

Hyperphosphorylation of mouse cardiac titin contributes to transverse aortic constriction-induced diastolic dysfunction.

Hudson B, Hidalgo C, Saripalli C, Granzier H.

Circ Res. 2011 Sep 30;109(8):858-66. doi: 10.1161/CIRCRESAHA.111.246819. Epub 2011 Aug 11.

18.

Differential expression of cardiac titin isoforms and modulation of cellular stiffness.

Cazorla O, Freiburg A, Helmes M, Centner T, McNabb M, Wu Y, Trombitás K, Labeit S, Granzier H.

Circ Res. 2000 Jan 7-21;86(1):59-67.

19.
20.

Changes in titin and collagen underlie diastolic stiffness diversity of cardiac muscle.

Wu Y, Cazorla O, Labeit D, Labeit S, Granzier H.

J Mol Cell Cardiol. 2000 Dec;32(12):2151-62.

PMID:
11112991

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