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Items: 1 to 20 of 178

1.

Activation of the Slx5-Slx8 ubiquitin ligase by poly-small ubiquitin-like modifier conjugates.

Mullen JR, Brill SJ.

J Biol Chem. 2008 Jul 18;283(29):19912-21. doi: 10.1074/jbc.M802690200. Epub 2008 May 22.

2.

The SUMO-targeted ubiquitin ligase subunit Slx5 resides in nuclear foci and at sites of DNA breaks.

Cook CE, Hochstrasser M, Kerscher O.

Cell Cycle. 2009 Apr 1;8(7):1080-9. Epub 2009 Apr 9.

3.

Quality control of a transcriptional regulator by SUMO-targeted degradation.

Wang Z, Prelich G.

Mol Cell Biol. 2009 Apr;29(7):1694-706. doi: 10.1128/MCB.01470-08. Epub 2009 Jan 12.

4.

The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation.

Xie Y, Kerscher O, Kroetz MB, McConchie HF, Sung P, Hochstrasser M.

J Biol Chem. 2007 Nov 23;282(47):34176-84. Epub 2007 Sep 11.

5.

Wss1 is a SUMO-dependent isopeptidase that interacts genetically with the Slx5-Slx8 SUMO-targeted ubiquitin ligase.

Mullen JR, Chen CF, Brill SJ.

Mol Cell Biol. 2010 Aug;30(15):3737-48. doi: 10.1128/MCB.01649-09. Epub 2010 Jun 1.

6.

Stimulation of in vitro sumoylation by Slx5-Slx8: evidence for a functional interaction with the SUMO pathway.

Ii T, Mullen JR, Slagle CE, Brill SJ.

DNA Repair (Amst). 2007 Nov;6(11):1679-91. Epub 2007 Jul 31.

7.

PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL.

Horigome C, Bustard DE, Marcomini I, Delgoshaie N, Tsai-Pflugfelder M, Cobb JA, Gasser SM.

Genes Dev. 2016 Apr 15;30(8):931-45. doi: 10.1101/gad.277665.116. Epub 2016 Apr 7.

8.

Distinct SUMO ligases cooperate with Esc2 and Slx5 to suppress duplication-mediated genome rearrangements.

Albuquerque CP, Wang G, Lee NS, Kolodner RD, Putnam CD, Zhou H.

PLoS Genet. 2013;9(8):e1003670. doi: 10.1371/journal.pgen.1003670. Epub 2013 Aug 1. Erratum in: PLoS Genet. 2016 Aug;12(8):e1006302.

9.

Ubiquitin-dependent proteolytic control of SUMO conjugates.

Uzunova K, Göttsche K, Miteva M, Weisshaar SR, Glanemann C, Schnellhardt M, Niessen M, Scheel H, Hofmann K, Johnson ES, Praefcke GJ, Dohmen RJ.

J Biol Chem. 2007 Nov 23;282(47):34167-75. Epub 2007 Aug 29.

10.

Disruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells.

Böhm S, Mihalevic MJ, Casal MA, Bernstein KA.

DNA Repair (Amst). 2015 Feb;26:1-14. doi: 10.1016/j.dnarep.2014.12.004. Epub 2014 Dec 26.

11.

A SUMO-targeted ubiquitin ligase is involved in the degradation of the nuclear pool of the SUMO E3 ligase Siz1.

Westerbeck JW, Pasupala N, Guillotte M, Szymanski E, Matson BC, Esteban C, Kerscher O.

Mol Biol Cell. 2014 Jan;25(1):1-16. doi: 10.1091/mbc.E13-05-0291. Epub 2013 Nov 6.

12.

A Lysine Desert Protects a Novel Domain in the Slx5-Slx8 SUMO Targeted Ub Ligase To Maintain Sumoylation Levels in Saccharomyces cerevisiae.

Sharma P, Mullen JR, Li M, Zaratiegui M, Bunting SF, Brill SJ.

Genetics. 2017 Aug;206(4):1807-1821. doi: 10.1534/genetics.117.202697. Epub 2017 May 26.

PMID:
28550017
13.

Genetic evidence that polysumoylation bypasses the need for a SUMO-targeted Ub ligase.

Mullen JR, Das M, Brill SJ.

Genetics. 2011 Jan;187(1):73-87. doi: 10.1534/genetics.110.124347. Epub 2010 Nov 8.

14.

SUMO Pathway Modulation of Regulatory Protein Binding at the Ribosomal DNA Locus in Saccharomyces cerevisiae.

Gillies J, Hickey CM, Su D, Wu Z, Peng J, Hochstrasser M.

Genetics. 2016 Apr;202(4):1377-94. doi: 10.1534/genetics.116.187252. Epub 2016 Feb 2.

15.

SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor.

Xie Y, Rubenstein EM, Matt T, Hochstrasser M.

Genes Dev. 2010 May;24(9):893-903. doi: 10.1101/gad.1906510. Epub 2010 Apr 13.

16.

The yeast Slx5-Slx8 DNA integrity complex displays ubiquitin ligase activity.

Ii T, Fung J, Mullen JR, Brill SJ.

Cell Cycle. 2007 Nov 15;6(22):2800-9. Epub 2007 Aug 13.

17.

The Slx5-Slx8 complex affects sumoylation of DNA repair proteins and negatively regulates recombination.

Burgess RC, Rahman S, Lisby M, Rothstein R, Zhao X.

Mol Cell Biol. 2007 Sep;27(17):6153-62. Epub 2007 Jun 25.

18.

Slx5/Slx8 Promotes Replication Stress Tolerance by Facilitating Mitotic Progression.

Thu YM, Van Riper SK, Higgins L, Zhang T, Becker JR, Markowski TW, Nguyen HD, Griffin TJ, Bielinsky AK.

Cell Rep. 2016 May 10;15(6):1254-65. doi: 10.1016/j.celrep.2016.04.017. Epub 2016 Apr 28.

19.

Purification of the yeast Slx5-Slx8 protein complex and characterization of its DNA-binding activity.

Yang L, Mullen JR, Brill SJ.

Nucleic Acids Res. 2006;34(19):5541-51. Epub 2006 Oct 4.

20.

SIM-dependent enhancement of substrate-specific SUMOylation by a ubiquitin ligase in vitro.

Parker JL, Ulrich HD.

Biochem J. 2014 Feb 1;457(3):435-40. doi: 10.1042/BJ20131381.

PMID:
24224485

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