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Items: 1 to 20 of 102

1.

Regulatory polymorphisms and their contribution to interindividual differences in the expression of enzymes influencing drug and toxicant disposition.

Hines RN, Koukouritaki SB, Poch MT, Stephens MC.

Drug Metab Rev. 2008;40(2):263-301. doi: 10.1080/03602530801952682 . Review.

PMID:
18464046
2.

Genetic polymorphisms in drug-metabolizing enzymes and drug targets.

Hiratsuka M, Mizugaki M.

Mol Genet Metab. 2001 Aug;73(4):298-305. Review. No abstract available.

PMID:
11509011
3.

Polymorphisms affecting gene regulation and mRNA processing: broad implications for pharmacogenetics.

Johnson AD, Wang D, Sadee W.

Pharmacol Ther. 2005 Apr;106(1):19-38. Epub 2004 Dec 15. Review.

PMID:
15781120
4.

Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines.

Brandon EF, Bosch TM, Deenen MJ, Levink R, van der Wal E, van Meerveld JB, Bijl M, Beijnen JH, Schellens JH, Meijerman I.

Toxicol Appl Pharmacol. 2006 Feb 15;211(1):1-10. Epub 2005 Jun 21.

PMID:
15975613
5.

The biochemistry of drug metabolism--an introduction: part 6. Inter-individual factors affecting drug metabolism.

Krämer SD, Testa B.

Chem Biodivers. 2008 Dec;5(12):2465-578. doi: 10.1002/cbdv.200890214. Review. Erratum in: Chem Biodivers. 2009 Jul;6(7):1144.

PMID:
19089818
6.

Genetic polymorphisms in human drug-metabolizing enzymes: potential uses of reverse genetics to identify genes of toxicological relevance.

Puga A, Nebert DW, McKinnon RA, Menon AG.

Crit Rev Toxicol. 1997 Mar;27(2):199-222. Review.

PMID:
9099519
7.

Ontogeny of drug metabolizing enzymes in the neonate.

Blake MJ, Castro L, Leeder JS, Kearns GL.

Semin Fetal Neonatal Med. 2005 Apr;10(2):123-38. Epub 2005 Jan 25. Review.

PMID:
15701578
8.

Epigenetic regulation of genes encoding drug-metabolizing enzymes and transporters; DNA methylation and other mechanisms.

Hirota T, Takane H, Higuchi S, Ieiri I.

Curr Drug Metab. 2008 Jan;9(1):34-8. Review.

PMID:
18220569
9.
10.
11.

[Overview: molecular variation, specific tissue localization and genetic polymorphisms of drug transporters].

Sugiyama Y, Maeda K.

Nihon Yakurigaku Zasshi. 2005 Apr;125(4):178-84. Review. Japanese. No abstract available.

PMID:
15930793
12.

Biomarkers in aquatic plants: selection and utility.

Brain RA, Cedergreen N.

Rev Environ Contam Toxicol. 2009;198:49-109. doi: 10.1007/978-0-387-09647-6_2. Review.

PMID:
19253039
13.

So many studies, too few subjects: establishing functional relevance of genetic polymorphisms on pharmacokinetics.

Williams JA, Johnson K, Paulauskis J, Cook J.

J Clin Pharmacol. 2006 Mar;46(3):258-64.

PMID:
16490801
14.

Validation of the performance of a comprehensive genotyping assay panel of single nucleotide polymorphisms in drug metabolism enzyme genes.

Welch RA, Lazaruk K, Haque KA, Hyland F, Xiao N, Wronka L, Burdett L, Chanock SJ, Ingber D, De La Vega FM, Yeager M.

Hum Mutat. 2008 May;29(5):750-6. doi: 10.1002/humu.20703.

PMID:
18327779
15.

Genetically determined polymorphisms in drug oxidation.

Jacqz E, Hall SD, Branch RA.

Hepatology. 1986 Sep-Oct;6(5):1020-32. No abstract available.

PMID:
3758933
16.

Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes.

Okey AB, Boutros PC, Harper PA.

Pharmacogenet Genomics. 2005 Jun;15(6):371-9. Review.

PMID:
15900209
17.

Genetic polymorphisms of drug-metabolizing enzymes: molecular mechanisms.

Meyer UA, Zanger U, Skoda R, Grant DM.

Psychopharmacol Ser. 1989;7:141-7. Review. No abstract available.

PMID:
2687852
18.
19.

Polymorphism of human cytochrome P450 enzymes and its clinical impact.

Zhou SF, Liu JP, Chowbay B.

Drug Metab Rev. 2009;41(2):89-295. doi: 10.1080/03602530902843483. Review.

PMID:
19514967
20.

Genetic polymorphisms in human drug metabolic enzymes.

Miller MS, McCarver DG, Bell DA, Eaton DL, Goldstein JA.

Fundam Appl Toxicol. 1997 Nov;40(1):1-14. Review.

PMID:
9398483

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