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Genetic epidemiology of subclinical cardiovascular disease in the diabetes heart study.

Bowden DW, Lehtinen AB, Ziegler JT, Rudock ME, Xu J, Wagenknecht LE, Herrington DM, Rich SS, Freedman BI, Carr JJ, Langefeld CD.

Ann Hum Genet. 2008 Sep;72(Pt 5):598-610. doi: 10.1111/j.1469-1809.2008.00446.x. Epub 2008 Apr 29.


Coincident linkage of type 2 diabetes, metabolic syndrome, and measures of cardiovascular disease in a genome scan of the diabetes heart study.

Bowden DW, Rudock M, Ziegler J, Lehtinen AB, Xu J, Wagenknecht LE, Herrington D, Rich SS, Freedman BI, Carr JJ, Langefeld CD.

Diabetes. 2006 Jul;55(7):1985-94.


Genetic mapping of vascular calcified plaque loci on chromosome 16p in European Americans from the diabetes heart study.

Lehtinen AB, Cox AJ, Ziegler JT, Voruganti VS, Xu J, Freedman BI, Carr JJ, Comuzzie AG, Langefeld CD, Bowden DW.

Ann Hum Genet. 2011 Mar;75(2):222-35. doi: 10.1111/j.1469-1809.2010.00632.x.


Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study.

Burdon KP, Lehtinen AB, Langefeld CD, Carr JJ, Rich SS, Freedman BI, Herrington D, Bowden DW.

Diab Vasc Dis Res. 2008 Jun;5(2):128-34. doi: 10.3132/dvdr.2008.021.


Analysis of common and coding variants with cardiovascular disease in the Diabetes Heart Study.

Adams JN, Raffield LM, Freedman BI, Langefeld CD, Ng MC, Carr JJ, Cox AJ, Bowden DW.

Cardiovasc Diabetol. 2014 Apr 12;13:77. doi: 10.1186/1475-2840-13-77.


The impact of ethnicity and sex on subclinical cardiovascular disease: the Diabetes Heart Study.

Freedman BI, Hsu FC, Langefeld CD, Rich SS, Herrington DM, Carr JJ, Xu J, Bowden DW, Wagenknecht LE.

Diabetologia. 2005 Dec;48(12):2511-8. Epub 2005 Nov 1.


Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus.

Divers J, Palmer ND, Lu L, Register TC, Carr JJ, Hicks PJ, Hightower RC, Smith SC, Xu J, Cox AJ, Hruska KA, Bowden DW, Lewis CE, Heiss G, Province MA, Borecki IB, Kerr KF, Chen YD, Palmas W, Rotter JI, Wassel CL, Bertoni AG, Herrington DM, Wagenknecht LE, Langefeld CD, Freedman BI.

Circ Cardiovasc Genet. 2013 Feb;6(1):97-105. doi: 10.1161/CIRCGENETICS.112.964114. Epub 2012 Dec 11.


Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group.

Malhotra A, Igo RP Jr, Thameem F, Kao WH, Abboud HE, Adler SG, Arar NH, Bowden DW, Duggirala R, Freedman BI, Goddard KA, Ipp E, Iyengar SK, Kimmel PL, Knowler WC, Kohn O, Leehey D, Meoni LA, Nelson RG, Nicholas SB, Parekh RS, Rich SS, Chen YD, Saad MF, Scavini M, Schelling JR, Sedor JR, Shah VO, Taylor KD, Thornley-Brown D, Zager PG, Horvath A, Hanson RL; Family Investigation of Nephropathy and Diabetes Research Group.

Diabetes Metab Res Rev. 2009 Nov;25(8):740-7. doi: 10.1002/dmrr.1031.


Genome-wide linkage scan in Gullah-speaking African American families with type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR).

Sale MM, Lu L, Spruill IJ, Fernandes JK, Lok KH, Divers J, Langefeld CD, Garvey WT.

Diabetes. 2009 Jan;58(1):260-7. doi: 10.2337/db08-0198. Epub 2008 Oct 3.


Polymorphisms in the Selenoprotein S gene and subclinical cardiovascular disease in the Diabetes Heart Study.

Cox AJ, Lehtinen AB, Xu J, Langefeld CD, Freedman BI, Carr JJ, Bowden DW.

Acta Diabetol. 2013 Jun;50(3):391-9. doi: 10.1007/s00592-012-0440-z. Epub 2012 Nov 16.


A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27.

Francke S, Manraj M, Lacquemant C, Lecoeur C, LeprĂȘtre F, Passa P, Hebe A, Corset L, Yan SL, Lahmidi S, Jankee S, Gunness TK, Ramjuttun US, Balgobin V, Dina C, Froguel P.

Hum Mol Genet. 2001 Nov 15;10(24):2751-65.


Genetic epidemiology and genome-wide linkage analysis of carotid artery ultrasound traits in multigenerational African ancestry families.

Kuipers AL, Kammerer CM, Miljkovic I, Woodard GA, Bunker CH, Patrick AL, Wheeler VW, Newman AB, Zmuda JM.

Atherosclerosis. 2013 Nov;231(1):120-3. doi: 10.1016/j.atherosclerosis.2013.09.005. Epub 2013 Sep 11.


Genetic analysis of haptoglobin polymorphisms with cardiovascular disease and type 2 diabetes in the Diabetes Heart Study.

Adams JN, Cox AJ, Freedman BI, Langefeld CD, Carr JJ, Bowden DW.

Cardiovasc Diabetol. 2013 Feb 11;12:31. doi: 10.1186/1475-2840-12-31.


A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND).

Thameem F, Igo RP Jr, Freedman BI, Langefeld C, Hanson RL, Schelling JR, Elston RC, Duggirala R, Nicholas SB, Goddard KA, Divers J, Guo X, Ipp E, Kimmel PL, Meoni LA, Shah VO, Smith MW, Winkler CA, Zager PG, Knowler WC, Nelson RG, Pahl MV, Parekh RS, Kao WH, Rasooly RS, Adler SG, Abboud HE, Iyengar SK, Sedor JR; Family Investigation of Nephropathy and Diabetes Research Group.

PLoS One. 2013 Dec 17;8(12):e81888. doi: 10.1371/journal.pone.0081888. eCollection 2013.


Loci contributing to adult height and body mass index in African American families ascertained for type 2 diabetes.

Sale MM, Freedman BI, Hicks PJ, Williams AH, Langefeld CD, Gallagher CJ, Bowden DW, Rich SS.

Ann Hum Genet. 2005 Sep;69(Pt 5):517-27.


A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q.

Wiltshire S, Hattersley AT, Hitman GA, Walker M, Levy JC, Sampson M, O'Rahilly S, Frayling TM, Bell JI, Lathrop GM, Bennett A, Dhillon R, Fletcher C, Groves CJ, Jones E, Prestwich P, Simecek N, Rao PV, Wishart M, Bottazzo GF, Foxon R, Howell S, Smedley D, Cardon LR, Menzel S, McCarthy MI.

Am J Hum Genet. 2001 Sep;69(3):553-69. Epub 2001 Aug 1. Erratum in: Am J Hum Genet 2002 Apr;70(4):1075.


Variants in adiponectin signaling pathway genes show little association with subclinical CVD in the diabetes heart study.

Cox AJ, Lambird JE, An SS, Register TC, Langefeld CD, Carr JJ, Freedman BI, Bowden DW.

Obesity (Silver Spring). 2013 Sep;21(9):E456-62. doi: 10.1002/oby.20184. Epub 2013 May 13.


Heritability of carotid artery intima-medial thickness in type 2 diabetes.

Lange LA, Bowden DW, Langefeld CD, Wagenknecht LE, Carr JJ, Rich SS, Riley WA, Freedman BI.

Stroke. 2002 Jul;33(7):1876-81.


Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes.

Divers J, Palmer ND, Langefeld CD, Brown WM, Lu L, Hicks PJ, Smith SC, Xu J, Terry JG, Register TC, Wagenknecht LE, Parks JS, Ma L, Chan GC, Buxbaum SG, Correa A, Musani S, Wilson JG, Taylor HA, Bowden DW, Carr JJ, Freedman BI.

BMC Genet. 2017 Dec 8;18(1):105. doi: 10.1186/s12863-017-0572-9.


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