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Reperfusion half-life: a novel pharmacodynamic measure of thrombolytic activity.

Merino JG, Latour LL, An L, Hsia AW, Kang DW, Warach S.

Stroke. 2008 Jul;39(7):2148-50. doi: 10.1161/STROKEAHA.107.510818. Epub 2008 May 1.


Systematic review of outcome after ischemic stroke due to anterior circulation occlusion treated with intravenous, intra-arterial, or combined intravenous+intra-arterial thrombolysis.

Mullen MT, Pisapia JM, Tilwa S, Messé SR, Stein SC.

Stroke. 2012 Sep;43(9):2350-5. doi: 10.1161/STROKEAHA.111.639211. Epub 2012 Jul 17. Review.


Reperfusion after 4.5 hours reduces infarct growth and improves clinical outcomes.

Picanço MR, Christensen S, Campbell BC, Churilov L, Parsons MW, Desmond PM, Barber PA, Levi CR, Bladin CF, Donnan GA, Davis SM; EPITHET Investigators..

Int J Stroke. 2014 Apr;9(3):266-9. doi: 10.1111/ijs.12209. Epub 2013 Nov 21.


A multicenter, randomized, controlled study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits with Intra-Arterial therapy (EXTEND-IA).

Campbell BC, Mitchell PJ, Yan B, Parsons MW, Christensen S, Churilov L, Dowling RJ, Dewey H, Brooks M, Miteff F, Levi C, Krause M, Harrington TJ, Faulder KC, Steinfort BS, Kleinig T, Scroop R, Chryssidis S, Barber A, Hope A, Moriarty M, McGuinness B, Wong AA, Coulthard A, Wijeratne T, Lee A, Jannes J, Leyden J, Phan TG, Chong W, Holt ME, Chandra RV, Bladin CF, Badve M, Rice H, de Villiers L, Ma H, Desmond PM, Donnan GA, Davis SM; EXTEND-IA investigators..

Int J Stroke. 2014 Jan;9(1):126-32. doi: 10.1111/ijs.12206. Epub 2013 Nov 10.


Reperfusion therapy in unclear-onset stroke based on MRI evaluation (RESTORE): a prospective multicenter study.

Kang DW, Sohn SI, Hong KS, Yu KH, Hwang YH, Han MK, Lee J, Park JM, Cho AH, Kim HJ, Kim DE, Cho YJ, Koo J, Yun SC, Kwon SU, Bae HJ, Kim JS.

Stroke. 2012 Dec;43(12):3278-83. doi: 10.1161/STROKEAHA.112.675926. Epub 2012 Oct 23.


Diffusion- and perfusion-weighted MRI response to thrombolysis in stroke.

Parsons MW, Barber PA, Chalk J, Darby DG, Rose S, Desmond PM, Gerraty RP, Tress BM, Wright PM, Donnan GA, Davis SM.

Ann Neurol. 2002 Jan;51(1):28-37.


Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke.

Higashida RT, Furlan AJ, Roberts H, Tomsick T, Connors B, Barr J, Dillon W, Warach S, Broderick J, Tilley B, Sacks D; Technology Assessment Committee of the American Society of Interventional and Therapeutic Neuroradiology.; Technology Assessment Committee of the Society of Interventional Radiology..

Stroke. 2003 Aug;34(8):e109-37. Epub 2003 Jul 17. Erratum in: Stroke. 2003 Nov;34(11):2774.


Stroke lesion volumes and outcome are not different in hemispheric stroke side treated with intravenous thrombolysis based on magnetic resonance imaging criteria.

Golsari A, Cheng B, Sobesky J, Schellinger PD, Fiehler J, Gerloff C, Thomalla G.

Stroke. 2015 Apr;46(4):1004-8. doi: 10.1161/STROKEAHA.114.007292. Epub 2015 Feb 19.


Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial.

Davis SM, Donnan GA, Parsons MW, Levi C, Butcher KS, Peeters A, Barber PA, Bladin C, De Silva DA, Byrnes G, Chalk JB, Fink JN, Kimber TE, Schultz D, Hand PJ, Frayne J, Hankey G, Muir K, Gerraty R, Tress BM, Desmond PM; EPITHET investigators..

Lancet Neurol. 2008 Apr;7(4):299-309. doi: 10.1016/S1474-4422(08)70044-9. Epub 2008 Feb 28.


Time to angiographic reperfusion in acute ischemic stroke: decision analysis.

Vagal AS, Khatri P, Broderick JP, Tomsick TA, Yeatts SD, Eckman MH.

Stroke. 2014 Dec;45(12):3625-30. doi: 10.1161/STROKEAHA.114.007188. Epub 2014 Oct 28.


Susceptibility-weighted imaging for cerebral microbleed detection in super-acute ischemic stroke patients treated with intravenous thrombolysis.

Bai Q, Zhao Z, Sui H, Xie X, Chen J, Yang J, Zhang L.

Neurol Res. 2013 Jul;35(6):586-93. doi: 10.1179/1743132813Y.0000000179. Epub 2013 Feb 22.


MRI screening before standard tissue plasminogen activator therapy is feasible and safe.

Kang DW, Chalela JA, Dunn W, Warach S; NIH-Suburban Stroke Center Investigators..

Stroke. 2005 Sep;36(9):1939-43. Epub 2005 Aug 4.


Perfusion computed tomography-guided intravenous thrombolysis for acute ischemic stroke beyond 4.5 hours: a case-control study.

García-Bermejo P, Calleja AI, Pérez-Fernández S, Cortijo E, del Monte JM, García-Porrero M, Fe Muñoz M, Fernández-Herranz R, Arenillas JF.

Cerebrovasc Dis. 2012;34(1):31-7. doi: 10.1159/000338778. Epub 2012 Jun 29.


Relationships Between Imaging Assessments and Outcomes in Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke.

Albers GW, Goyal M, Jahan R, Bonafe A, Diener HC, Levy EI, Pereira VM, Cognard C, Yavagal DR, Saver JL.

Stroke. 2015 Oct;46(10):2786-94. doi: 10.1161/STROKEAHA.115.010710. Epub 2015 Aug 27.


Reperfusion after thrombolytic therapy of embolic stroke in the rat: magnetic resonance and biochemical imaging.

Busch E, Krüger K, Allegrini PR, Kerskens CM, Gyngell ML, Hoehn-Berlage M, Hossmann KA.

J Cereb Blood Flow Metab. 1998 Apr;18(4):407-18.


Annexin A2: a tissue plasminogen activator amplifier for thrombolytic stroke therapy.

Fan X, Yu Z, Liu J, Liu N, Hajjar KA, Furie KL, Lo EH, Wang X.

Stroke. 2010 Oct;41(10 Suppl):S54-8. doi: 10.1161/STROKEAHA.110.596106.


Assessing reperfusion and recanalization as markers of clinical outcomes after intravenous thrombolysis in the echoplanar imaging thrombolytic evaluation trial (EPITHET).

De Silva DA, Fink JN, Christensen S, Ebinger M, Bladin C, Levi CR, Parsons M, Butcher K, Barber PA, Donnan GA, Davis SM; Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators..

Stroke. 2009 Aug;40(8):2872-4. doi: 10.1161/STROKEAHA.108.543595. Epub 2009 May 28.


Brain imaging modality before systemic thrombolysis for ischemic stroke within three hours.

Uenaka T, Yoneda Y, Yamamoto S, Hara Y, Yamashita H.

Eur Neurol. 2010;64(4):241-5. doi: 10.1159/000319918. Epub 2010 Sep 7.


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