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18445624,18930992,17561354,18576303,19950259,12064832,19479858,11502611,17498268,19262492,15593213,11550967,17384178,17389013,22169458,18588853,16802365,20064083,15585313,16882174,18263595,17962369,21875883,17133607,17014016,12858451,17504511,17444587,18713787,17584583,19644887,18381789,23285481,17665460,20231204,19211583,19208687,18706680,16775619,22045841,17604287,18412309,8730118,12115192,17295440,12528120,20131239,21898345,18666137,17133608,21971214,16473667,25062418,15289903,17667965,16947775,16180014,12428242,15801017,19240174,17459075,19602000,15500644,11824955,17392350,16467040,14705223,16278285,11528521,23237063,18798060,16255757,15479907,19966313,21504484,11465719,11708418,19168581,9818655,19524188,19004037,11508588,11036836,18203319,15546965,16385516,15266059,19333920,16584113,15567898,22299671,17599774,32185220,18003662,15476238,16157125,15797972,19286670,11083280,16112028,25572744,17938571,17309887,15624175,18203317,15583989,19758203,19214870,21864851,18085738,20595276,17708363,25880423,17763164,19603010,22247367,20824279,22820628,16159952,10990228,16135682,16449364,18383830,18483392,17183065,17552041,23707908,18576347,17576235,19062735,15104684,17657791,12847690,17234652,22984273,20032097,22211766,21875377,28668810,18093183,19136037,16813666,18272670,34665708,18081831,17117486,18617551,25959492,15748958,18312459,18569989,18438838,17591062,20603050,16802363,18449419,17075815,9517764,18484687,19083997,14668093,24613044,16426919,19716115,18599322,24690069,18615253,18753860,19631630,17515941,16385514,11465718,16981293,17056024,19021012,28002595,19035499,32315557,18375974,17924608,14872101,18174230,14992821,12784397,21149496,31682743,20517890,17855424,20682663,18025848,8895149,18312458,34276673,25274885,22723597,16119673,12784395,17606463,18090928,16142866,36968636,12508774,17762757,17010329,20511617,12746909,31916109,12515395,15199216,18051225,18028496,26416393,18322986,17937467,8756980,17522098,15530459,17985401,22386066,15147363,21890620,30641535,12966604,22753661,24016306,21905008,21131644,21159834,28749191,22045834,15459814,17563404,22589256,18397302,19054818,25228505,24591477,31234888,15114270,29030005,28980912,25293362,20464037,19538867,26712637,15213329,16507928,15218339,17868256,23755762,16325272,20090527,27906879,11296950,20551103,16084222,18375538,16891653,9870923,15183145,18336639,21187296,17504509,17465232,24348139,32175889,16265695,20391488,9617437,21162102,17493148,24389298,19054816,19877059,27056741,17704068,20346932,17896803,16936331,22012429,19293162,18325332,26338035,18074864,21779708,17321603,11315930,29948346,21779181,20967855,23591741,17617473,10817560,27098064,28534442,21366713,26743213,17609672,16508979,16864101,15804707,25986483,21480188,17961776,15135176,19815934,23287360,26546534,24488411,17937468,21763380,12136892,35348643,31375891,16126963,21615510,17426141,30940202,31353423,26076711,29432441,30771500,16870103,16573784,28160477,16712644,17942087,26350483,23983073,8913653,23754244,17727371,15654958,15692963,32253703,16636934,22742541,16580263,17784951,17599771,32144871,19918037,21936615,23270786,24718960,19719928,18022620,17133611,19032828,24574233,17313882,10551674,19132786,24665877,16832842,34096881,23818915,18084000,22402147,18302883,27520796,25847615,22382346,23940607,21455563,19116937,21520010,17660220,30685360,17584599,21926187,28631694,17101293,8129794,27385538,19796918,29294089,33787070,16956435,17317613,25030848,2406810,18073456,17050587,18077490,11136875,22440820,35319814,18528529,26163687,28240591,31838157,9225871,19950302,12618866,22422496,17166870,17117485,12528118,19808694,28229829,33580257,31969223,12846047,18000232,26314374,21961844,16960901,10694840,10685806,28952189,19210862,17643929,16709489,16261285,33555460,24261765,13130480,21362770,36868782,22247218,17881752,26615410,26186532,10555893,30008455,17785309,23172754,36561716,28124759,30767873,17125598,11263781,19306159,22661184,17525707,36977758,24503734,22731751,26792595,25024353,23873879,35532783,18390561,30947741,19778912,35633574,12207584,26672963,12907599,19032966,21474487,19444434,17599775,10733477,11600746,20395645,16108814,25582539,24292093,14705224,27134252,16740682,19480241,12117671,15880831,18493769,18269077,20863905,32696043,17564320,22763041,18515867,25885360,28434122,36301368,20616736,35997480,20424538,33973825,23141929,11136877,23444193,10600011,23228394,21586211,27550299,23543079,23397258,18092267,17041464,19696067,18216574,30008641,29869154,36675584,16617751,11312377,27111861,23027890,21790288,16832637,17710842,33495915,33197579,21052675,24448373,15220464,23200754,17631732,35876828,21085492,30586461,29342503,31538512,20080908,35358372,17876529,18057462,19298528,25658605,21658325,12820690,27718018,28070535,22489299,17457599,17143677,24330664,33933370,18588573,29242839,27134258,19447773,12188927,26669670,33514797,26338038,22298186,9393960,18278837,15183103,33274678,34643357,22563211,27677579,29769578,17767744,11830429,17477471,21571730,26000117,29541461,28617356,17440718,17917539,27079850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620 results

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The -670G>A polymorphism in the FAS gene promoter region influences the susceptibility to systemic sclerosis.

Liakouli V, Manetti M, Pacini A, Tolusso B, Fatini C, Toscano A, Cipriani P, Guiducci S, Bazzichi L, Codullo V, Ruocco L, Dell'orso L, Carubbi F, Marrelli A, Abbate R, Bombardieri S, Ferraccioli G, Montecucco C, Valentini G, Matucci-Cerinic M, Ibba-Manneschi L, Giacomelli R. Liakouli V, et al. Ann Rheum Dis. 2009 Apr;68(4):584-90. doi: 10.1136/ard.2008.088989. Epub 2008 Apr 29. Ann Rheum Dis. 2009. PMID: 18445624

Association between a stromal cell-derived factor 1 (SDF-1/CXCL12) gene polymorphism and microvascular disease in systemic sclerosis.

Manetti M, Liakouli V, Fatini C, Cipriani P, Bonino C, Vettori S, Guiducci S, Montecucco C, Abbate R, Valentini G, Matucci-Cerinic M, Giacomelli R, Ibba-Manneschi L. Manetti M, et al. Ann Rheum Dis. 2009 Mar;68(3):408-11. doi: 10.1136/ard.2008.098277. Epub 2008 Oct 17. Ann Rheum Dis. 2009. PMID: 18930992

Role of BCL2 (ala43thr), CCND1 (G870A) and FAS (A-670G) polymorphisms in modulating the risk of developing esophageal cancer.

Jain M, Kumar S, Lal P, Tiwari A, Ghoshal UC, Mittal B. Jain M, et al. Cancer Detect Prev. 2007;31(3):225-32. doi: 10.1016/j.cdp.2007.04.005. Epub 2007 Jun 11. Cancer Detect Prev. 2007. PMID: 17561354

Ability of epistatic interactions of cytokine single-nucleotide polymorphisms to predict susceptibility to disease subsets in systemic sclerosis patients.

Beretta L, Cappiello F, Moore JH, Barili M, Greene CS, Scorza R. Beretta L, et al. Arthritis Rheum. 2008 Jul 15;59(7):974-83. doi: 10.1002/art.23836. Arthritis Rheum. 2008. PMID: 18576303 Free article.

The FAS -670A>G polymorphism influences susceptibility to systemic sclerosis phenotypes.

Broen J, Gourh P, Rueda B, Coenen M, Mayes M, Martin J, Arnett FC, Radstake TR; European Consortium on Systemic Sclerosis Genetics. Broen J, et al. Arthritis Rheum. 2009 Dec;60(12):3815-20. doi: 10.1002/art.24964. Arthritis Rheum. 2009. PMID: 19950259 Free PMC article.

A functional polymorphism in fas (CD95/APO-1) gene promoter associated with systemic lupus erythematosus.

Kanemitsu S, Ihara K, Saifddin A, Otsuka T, Takeuchi T, Nagayama J, Kuwano M, Hara T. Kanemitsu S, et al. J Rheumatol. 2002 Jun;29(6):1183-8. J Rheumatol. 2002. PMID: 12064832

Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population.

Ito I, Kawaguchi Y, Kawasaki A, Hasegawa M, Ohashi J, Hikami K, Kawamoto M, Fujimoto M, Takehara K, Sato S, Hara M, Tsuchiya N. Ito I, et al. Arthritis Rheum. 2009 Jun;60(6):1845-50. doi: 10.1002/art.24600. Arthritis Rheum. 2009. PMID: 19479858 Free article.

Serum TIMP-1, TIMP-2, and MMP-1 in patients with systemic sclerosis, primary Raynaud's phenomenon, and in normal controls.

Young-Min SA, Beeton C, Laughton R, Plumpton T, Bartram S, Murphy G, Black C, Cawston TE. Young-Min SA, et al. Ann Rheum Dis. 2001 Sep;60(9):846-51. Ann Rheum Dis. 2001. PMID: 11502611 Free PMC article.

Allograft inflammatory factor-1 and tumor necrosis factor single nucleotide polymorphisms in systemic sclerosis.

Otieno FG, Lopez AM, Jimenez SA, Gentiletti J, Artlett CM. Otieno FG, et al. Tissue Antigens. 2007 Jun;69(6):583-91. doi: 10.1111/j.1399-0039.2007.00830.x. Tissue Antigens. 2007. PMID: 17498268

Fas promoter region gene polymorphism is associated with an increased risk for myocardial infarction.

Hanasaki H, Takemura Y, Fukuo K, Ohishi M, Onishi M, Yasuda O, Katsuya T, Awata N, Kato N, Ogihara T, Rakugi H. Hanasaki H, et al. Hypertens Res. 2009 Apr;32(4):261-4. doi: 10.1038/hr.2009.2. Epub 2009 Feb 27. Hypertens Res. 2009. PMID: 19262492

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