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Items: 1 to 20 of 254

1.

Regulation of intra-S phase checkpoint by ionizing radiation (IR)-dependent and IR-independent phosphorylation of SMC3.

Luo H, Li Y, Mu JJ, Zhang J, Tonaka T, Hamamori Y, Jung SY, Wang Y, Qin J.

J Biol Chem. 2008 Jul 11;283(28):19176-83. doi: 10.1074/jbc.M802299200. Epub 2008 Apr 28.

2.

Genome-wide reinforcement of cohesin binding at pre-existing cohesin sites in response to ionizing radiation in human cells.

Kim BJ, Li Y, Zhang J, Xi Y, Li Y, Yang T, Jung SY, Pan X, Chen R, Li W, Wang Y, Qin J.

J Biol Chem. 2010 Jul 23;285(30):22784-92. doi: 10.1074/jbc.M110.134577. Epub 2010 May 25.

3.

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint.

Yazdi PT, Wang Y, Zhao S, Patel N, Lee EY, Qin J.

Genes Dev. 2002 Mar 1;16(5):571-82.

4.

Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage.

Lee JH, Xu B, Lee CH, Ahn JY, Song MS, Lee H, Canman CE, Lee JS, Kastan MB, Lim DS.

Mol Cancer Res. 2003 Jul;1(9):674-81.

5.
6.

Autophosphorylation and ATM activation: additional sites add to the complexity.

Kozlov SV, Graham ME, Jakob B, Tobias F, Kijas AW, Tanuji M, Chen P, Robinson PJ, Taucher-Scholz G, Suzuki K, So S, Chen D, Lavin MF.

J Biol Chem. 2011 Mar 18;286(11):9107-19. doi: 10.1074/jbc.M110.204065. Epub 2010 Dec 13.

7.

Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling.

Yamauchi M, Oka Y, Yamamoto M, Niimura K, Uchida M, Kodama S, Watanabe M, Sekine I, Yamashita S, Suzuki K.

DNA Repair (Amst). 2008 Mar 1;7(3):405-17. doi: 10.1016/j.dnarep.2007.11.011. Epub 2008 Jan 8.

PMID:
18248856
8.

Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK.

J Biol Chem. 2003 Apr 25;278(17):14806-11. Epub 2003 Feb 14.

9.

Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition.

Horton JK, Stefanick DF, Zeng JY, Carrozza MJ, Wilson SH.

DNA Repair (Amst). 2011 Feb 7;10(2):225-34. doi: 10.1016/j.dnarep.2010.11.003. Epub 2010 Dec 3.

10.

The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.

Stracker TH, Morales M, Couto SS, Hussein H, Petrini JH.

Nature. 2007 May 10;447(7141):218-21. Epub 2007 Apr 11.

11.

BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage.

Fabbro M, Savage K, Hobson K, Deans AJ, Powell SN, McArthur GA, Khanna KK.

J Biol Chem. 2004 Jul 23;279(30):31251-8. Epub 2004 May 24.

12.

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway.

Kitagawa R, Bakkenist CJ, McKinnon PJ, Kastan MB.

Genes Dev. 2004 Jun 15;18(12):1423-38. Epub 2004 Jun 2.

13.

DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM.

Dodson GE, Tibbetts RS.

J Biol Chem. 2006 Jan 20;281(3):1692-7. Epub 2005 Nov 17.

15.

Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.

Lee AY, Chiba T, Truong LN, Cheng AN, Do J, Cho MJ, Chen L, Wu X.

J Biol Chem. 2012 Jan 20;287(4):2531-43. doi: 10.1074/jbc.M111.291104. Epub 2011 Nov 28.

16.

Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways.

Taniguchi T, Garcia-Higuera I, Xu B, Andreassen PR, Gregory RC, Kim ST, Lane WS, Kastan MB, D'Andrea AD.

Cell. 2002 May 17;109(4):459-72.

17.

Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase.

Jin J, Ang XL, Ye X, Livingstone M, Harper JW.

J Biol Chem. 2008 Jul 11;283(28):19322-8. doi: 10.1074/jbc.M802474200. Epub 2008 May 13.

18.

The impact of heterochromatin on DSB repair.

Goodarzi AA, Noon AT, Jeggo PA.

Biochem Soc Trans. 2009 Jun;37(Pt 3):569-76. doi: 10.1042/BST0370569.

PMID:
19442252
19.

Coordinated action of the Fanconi anemia and ataxia telangiectasia pathways in response to oxidative damage.

Castillo P, Bogliolo M, Surralles J.

DNA Repair (Amst). 2011 May 5;10(5):518-25. doi: 10.1016/j.dnarep.2011.02.007. Epub 2011 Apr 5.

PMID:
21466974
20.

Enhanced radiation-mediated cell killing of human cervical cancer cells by small interference RNA silencing of ataxia telangiectasia-mutated protein.

Li W, Jian W, Xiaoping X, Yingfeng L, Tao X, Xiaoyan X.

Int J Gynecol Cancer. 2006 Jul-Aug;16(4):1620-30.

PMID:
16884376

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