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Items: 1 to 20 of 152


Division of labor at the eukaryotic replication fork.

Nick McElhinny SA, Gordenin DA, Stith CM, Burgers PM, Kunkel TA.

Mol Cell. 2008 Apr 25;30(2):137-44. doi: 10.1016/j.molcel.2008.02.022.


Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α.

Liberti SE, Larrea AA, Kunkel TA.

DNA Repair (Amst). 2013 Feb 1;12(2):92-6. doi: 10.1016/j.dnarep.2012.11.001. Epub 2012 Dec 11.


Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε.

Aksenova A, Volkov K, Maceluch J, Pursell ZF, Rogozin IB, Kunkel TA, Pavlov YI, Johansson E.

PLoS Genet. 2010 Nov 18;6(11):e1001209. doi: 10.1371/journal.pgen.1001209.


Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae.

Dubarry M, Lawless C, Banks AP, Cockell S, Lydall D.

G3 (Bethesda). 2015 Aug 21;5(10):2187-97. doi: 10.1534/g3.115.021493.


Dividing the workload at a eukaryotic replication fork.

Kunkel TA, Burgers PM.

Trends Cell Biol. 2008 Nov;18(11):521-7. doi: 10.1016/j.tcb.2008.08.005. Epub 2008 Sep 27. Review.


Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast.

Williams LN, Herr AJ, Preston BD.

Genetics. 2013 Mar;193(3):751-70. doi: 10.1534/genetics.112.146910. Epub 2013 Jan 10.


A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands.

Johnson RE, Klassen R, Prakash L, Prakash S.

Mol Cell. 2015 Jul 16;59(2):163-75. doi: 10.1016/j.molcel.2015.05.038. Epub 2015 Jul 2.


Replicative DNA polymerase δ but not ε proofreads errors in Cis and in Trans.

Flood CL, Rodriguez GP, Bao G, Shockley AH, Kow YW, Crouse GF.

PLoS Genet. 2015 Mar 5;11(3):e1005049. doi: 10.1371/journal.pgen.1005049. eCollection 2015 Mar.


CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication.

Langston LD, Zhang D, Yurieva O, Georgescu RE, Finkelstein J, Yao NY, Indiani C, O'Donnell ME.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15390-5. doi: 10.1073/pnas.1418334111. Epub 2014 Oct 13.


Yeast DNA polymerase epsilon participates in leading-strand DNA replication.

Pursell ZF, Isoz I, Lundström EB, Johansson E, Kunkel TA.

Science. 2007 Jul 6;317(5834):127-30.


Mismatch repair balances leading and lagging strand DNA replication fidelity.

Lujan SA, Williams JS, Pursell ZF, Abdulovic-Cui AA, Clark AB, Nick McElhinny SA, Kunkel TA.

PLoS Genet. 2012;8(10):e1003016. doi: 10.1371/journal.pgen.1003016. Epub 2012 Oct 11.


Evidence from mutational specificity studies that yeast DNA polymerases delta and epsilon replicate different DNA strands at an intracellular replication fork.

Karthikeyan R, Vonarx EJ, Straffon AF, Simon M, Faye G, Kunz BA.

J Mol Biol. 2000 Jun 2;299(2):405-19.


Fidelity consequences of the impaired interaction between DNA polymerase epsilon and the GINS complex.

Garbacz M, Araki H, Flis K, Bebenek A, Zawada AE, Jonczyk P, Makiela-Dzbenska K, Fijalkowska IJ.

DNA Repair (Amst). 2015 May;29:23-35. doi: 10.1016/j.dnarep.2015.02.007. Epub 2015 Feb 16.


The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA.

Chilkova O, Stenlund P, Isoz I, Stith CM, Grabowski P, Lundström EB, Burgers PM, Johansson E.

Nucleic Acids Res. 2007;35(19):6588-97. Epub 2007 Sep 28.


Ribonucleotides are signals for mismatch repair of leading-strand replication errors.

Lujan SA, Williams JS, Clausen AR, Clark AB, Kunkel TA.

Mol Cell. 2013 May 9;50(3):437-43. doi: 10.1016/j.molcel.2013.03.017. Epub 2013 Apr 18.


Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation.

Georgescu RE, Schauer GD, Yao NY, Langston LD, Yurieva O, Zhang D, Finkelstein J, O'Donnell ME.

Elife. 2015 Apr 14;4:e04988. doi: 10.7554/eLife.04988.


Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε.

Clark AB, Lujan SA, Kissling GE, Kunkel TA.

DNA Repair (Amst). 2011 May 5;10(5):476-82. doi: 10.1016/j.dnarep.2011.02.001. Epub 2011 Mar 16.


Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork.

Georgescu RE, Langston L, Yao NY, Yurieva O, Zhang D, Finkelstein J, Agarwal T, O'Donnell ME.

Nat Struct Mol Biol. 2014 Aug;21(8):664-70. doi: 10.1038/nsmb.2851. Epub 2014 Jul 6.


DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.

Albertson TM, Ogawa M, Bugni JM, Hays LE, Chen Y, Wang Y, Treuting PM, Heddle JA, Goldsby RE, Preston BD.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17101-4. doi: 10.1073/pnas.0907147106. Epub 2009 Sep 24.

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