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Items: 1 to 20 of 81

1.

Bromodomain 4 activation predicts breast cancer survival.

Crawford NP, Alsarraj J, Lukes L, Walker RC, Officewala JS, Yang HH, Lee MP, Ozato K, Hunter KW.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6380-5. doi: 10.1073/pnas.0710331105. Epub 2008 Apr 21.

2.

The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival.

Crawford NP, Walker RC, Lukes L, Officewala JS, Williams RW, Hunter KW.

Clin Exp Metastasis. 2008;25(4):357-69. doi: 10.1007/s10585-008-9146-6. Epub 2008 Feb 27.

3.

Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis.

Crawford NP, Qian X, Ziogas A, Papageorge AG, Boersma BJ, Walker RC, Lukes L, Rowe WL, Zhang J, Ambs S, Lowy DR, Anton-Culver H, Hunter KW.

PLoS Genet. 2007 Nov;3(11):e214. Epub 2007 Oct 16.

4.

Crk adaptor proteins act as key signaling integrators for breast tumorigenesis.

Fathers KE, Bell ES, Rajadurai CV, Cory S, Zhao H, Mourskaia A, Zuo D, Madore J, Monast A, Mes-Masson AM, Grosset AA, Gaboury L, Hallet M, Siegel P, Park M.

Breast Cancer Res. 2012 May 8;14(3):R74.

5.

Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.

Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP.

J Biol Chem. 2004 Dec 3;279(49):51630-46. Epub 2004 Sep 7.

6.

ITF2 is a target of CXCR4 in MDA-MB-231 breast cancer cells and is associated with reduced survival in estrogen receptor-negative breast cancer.

Appaiah H, Bhat-Nakshatri P, Mehta R, Thorat M, Badve S, Nakshatri H.

Cancer Biol Ther. 2010 Sep 15;10(6):600-14. Epub 2010 Sep 4.

7.

Polymorphisms of the SIPA1 gene and sporadic breast cancer susceptibility.

Hsieh SM, Smith RA, Lintell NA, Hunter KW, Griffiths LR.

BMC Cancer. 2009 Sep 18;9:331. doi: 10.1186/1471-2407-9-331.

8.

Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix.

Eckhardt BL, Parker BS, van Laar RK, Restall CM, Natoli AL, Tavaria MD, Stanley KL, Sloan EK, Moseley JM, Anderson RL.

Mol Cancer Res. 2005 Jan;3(1):1-13.

9.

Deletion of the proline-rich region of the murine metastasis susceptibility gene Brd4 promotes epithelial-to-mesenchymal transition- and stem cell-like conversion.

Alsarraj J, Walker RC, Webster JD, Geiger TR, Crawford NP, Simpson RM, Ozato K, Hunter KW.

Cancer Res. 2011 Apr 15;71(8):3121-31. doi: 10.1158/0008-5472.CAN-10-4417. Epub 2011 Mar 9.

10.

Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.

Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, Katiyar S, Zhou J, Dew E, Capozza F, Daumer KM, Minetti C, Milliman JN, Alpy F, Rio MC, Tomasetto C, Mercier I, Flomenberg N, Frank PG, Pestell RG, Lisanti MP.

Am J Pathol. 2009 May;174(5):1650-62. doi: 10.2353/ajpath.2009.080648.

11.

Nuclear SIPA1 activates integrin β1 promoter and promotes invasion of breast cancer cells.

Zhang Y, Gong Y, Hu D, Zhu P, Wang N, Zhang Q, Wang M, Aldeewan A, Xia H, Qu X, Ring BZ, Minato N, Su L.

Oncogene. 2015 Mar 12;34(11):1451-62. doi: 10.1038/onc.2014.36. Epub 2014 Apr 7.

PMID:
24704834
12.

Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer.

Mitra A, Fillmore RA, Metge BJ, Rajesh M, Xi Y, King J, Ju J, Pannell L, Shevde LA, Samant RS.

Breast Cancer Res. 2008;10(2):R22. doi: 10.1186/bcr1874. Epub 2008 Mar 7.

13.

BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane.

Alsarraj J, Faraji F, Geiger TR, Mattaini KR, Williams M, Wu J, Ha NH, Merlino T, Walker RC, Bosley AD, Xiao Z, Andresson T, Esposito D, Smithers N, Lugo D, Prinjha R, Day A, Crawford NP, Ozato K, Gardner K, Hunter KW.

PLoS One. 2013 Nov 19;8(11):e80746. doi: 10.1371/journal.pone.0080746. eCollection 2013.

14.
15.

Suppression of distant pulmonary metastasis of MDA-MB 435 human breast carcinoma established in mammary fat pads of nude mice by retroviral-mediated TIMP-2 gene transfer.

Lee YK, So IS, Lee SC, Lee JH, Lee CW, Kim WM, Park MK, Lee ST, Park DY, Shin DY, Park CU, Kim YS.

J Gene Med. 2005 Feb;7(2):145-57.

PMID:
15546163
16.

Metastatic canine mammary carcinomas can be identified by a gene expression profile that partly overlaps with human breast cancer profiles.

Klopfleisch R, Lenze D, Hummel M, Gruber AD.

BMC Cancer. 2010 Nov 9;10:618. doi: 10.1186/1471-2407-10-618.

17.

Exon-based clustering of murine breast tumor transcriptomes reveals alternative exons whose expression is associated with metastasis.

Dutertre M, Lacroix-Triki M, Driouch K, de la Grange P, Gratadou L, Beck S, Millevoi S, Tazi J, Lidereau R, Vagner S, Auboeuf D.

Cancer Res. 2010 Feb 1;70(3):896-905. doi: 10.1158/0008-5472.CAN-09-2703. Epub 2010 Jan 26.

18.

Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis.

Winter SF, Lukes L, Walker RC, Welch DR, Hunter KW.

PLoS Genet. 2012 May;8(5):e1002735. doi: 10.1371/journal.pgen.1002735. Epub 2012 May 31.

19.

Aberrant epigenetic regulation of bromodomain BRD4 in human colon cancer.

Rodriguez RM, Huidobro C, Urdinguio RG, Mangas C, Soldevilla B, Domínguez G, Bonilla F, Fernandez AF, Fraga MF.

J Mol Med (Berl). 2012 May;90(5):587-95. doi: 10.1007/s00109-011-0837-0. Epub 2011 Nov 27.

PMID:
22120039
20.

Anti-matrix metalloproteinase-9 DNAzyme decreases tumor growth in the MMTV-PyMT mouse model of breast cancer.

Hallett MA, Teng B, Hasegawa H, Schwab LP, Seagroves TN, Pourmotabbed T.

Breast Cancer Res. 2013 Feb 13;15(1):R12. doi: 10.1186/bcr3385.

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