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Items: 1 to 20 of 374

1.

Sirtuins in aging and disease.

Guarente L.

Cold Spring Harb Symp Quant Biol. 2007;72:483-8. doi: 10.1101/sqb.2007.72.024. Review.

PMID:
18419308
2.

Sirtuins: the 'magnificent seven', function, metabolism and longevity.

Dali-Youcef N, Lagouge M, Froelich S, Koehl C, Schoonjans K, Auwerx J.

Ann Med. 2007;39(5):335-45. Review.

PMID:
17701476
3.

The anti-aging, metabolism potential of SIRT1.

Ghosh HS.

Curr Opin Investig Drugs. 2008 Oct;9(10):1095-102. Review.

PMID:
18821472
4.

Calorie restriction--the SIR2 connection.

Guarente L, Picard F.

Cell. 2005 Feb 25;120(4):473-82. Review.

5.

Increase in activity during calorie restriction requires Sirt1.

Chen D, Steele AD, Lindquist S, Guarente L.

Science. 2005 Dec 9;310(5754):1641.

6.

Calorie restriction and SIR2 genes--towards a mechanism.

Guarente L.

Mech Ageing Dev. 2005 Sep;126(9):923-8. Review.

PMID:
15941577
7.

SirT1 regulates energy metabolism and response to caloric restriction in mice.

Boily G, Seifert EL, Bevilacqua L, He XH, Sabourin G, Estey C, Moffat C, Crawford S, Saliba S, Jardine K, Xuan J, Evans M, Harper ME, McBurney MW.

PLoS One. 2008 Mar 12;3(3):e1759. doi: 10.1371/journal.pone.0001759.

8.

SIRT1: roles in aging and cancer.

Kim EJ, Um SJ.

BMB Rep. 2008 Nov 30;41(11):751-6. Review.

9.

SIR2: a potential target for calorie restriction mimetics.

Chen D, Guarente L.

Trends Mol Med. 2007 Feb;13(2):64-71. Epub 2007 Jan 4. Review.

PMID:
17207661
10.

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction.

Haigis MC, Guarente LP.

Genes Dev. 2006 Nov 1;20(21):2913-21. Review.

11.

A therapeutic role for sirtuins in diseases of aging?

Westphal CH, Dipp MA, Guarente L.

Trends Biochem Sci. 2007 Dec;32(12):555-60. Epub 2007 Nov 5. Review.

PMID:
17980602
12.

Sir2 and calorie restriction in yeast: a skeptical perspective.

Kaeberlein M, Powers RW 3rd.

Ageing Res Rev. 2007 Aug;6(2):128-40. Epub 2007 Apr 19. Review.

PMID:
17512264
13.

Linking sirtuins, IGF-I signaling, and starvation.

Longo VD.

Exp Gerontol. 2009 Jan-Feb;44(1-2):70-4. doi: 10.1016/j.exger.2008.06.005. Epub 2008 Jun 24. Review.

PMID:
18638538
14.

Calorie restriction increases life span: a molecular mechanism.

Wolf G.

Nutr Rev. 2006 Feb;64(2 Pt 1):89-92. Review.

PMID:
16536186
15.

Cell biology. Twists in the tale of the aging yeast.

Rine J.

Science. 2005 Nov 18;310(5751):1124-5. No abstract available.

PMID:
16293743
16.

Life-span extension in yeast.

Sinclair DA, Lin SJ, Guarente L.

Science. 2006 Apr 14;312(5771):195-7; author reply 195-7. No abstract available.

PMID:
16614198
17.

The life span-prolonging effect of sirtuin-1 is mediated by autophagy.

Morselli E, Maiuri MC, Markaki M, Megalou E, Pasparaki A, Palikaras K, Criollo A, Galluzzi L, Malik SA, Vitale I, Michaud M, Madeo F, Tavernarakis N, Kroemer G.

Autophagy. 2010 Jan;6(1):186-8. Epub 2010 Jan 2. Review.

PMID:
20023410
18.

The enigmatic role of Sir2 in aging.

Kennedy BK, Smith ED, Kaeberlein M.

Cell. 2005 Nov 18;123(4):548-50.

19.

Mitochondrial respiration and reactive oxygen species in mitochondrial aging mutants.

Sedensky MM, Morgan PG.

Exp Gerontol. 2006 Mar;41(3):237-45. Epub 2006 Feb 21. Review.

PMID:
16497463
20.

Molecular links between aging and adipose tissue.

Picard F, Guarente L.

Int J Obes (Lond). 2005 Mar;29 Suppl 1:S36-9.

PMID:
15711582

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