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Items: 1 to 20 of 87

1.

Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells.

Serebriiskii I, Castelló-Cros R, Lamb A, Golemis EA, Cukierman E.

Matrix Biol. 2008 Jul;27(6):573-85. doi: 10.1016/j.matbio.2008.02.008.

2.

Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins.

Castelló-Cros R, Khan DR, Simons J, Valianou M, Cukierman E.

BMC Cancer. 2009 Mar 26;9:94. doi: 10.1186/1471-2407-9-94.

5.

FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells.

Lee HO, Mullins SR, Franco-Barraza J, Valianou M, Cukierman E, Cheng JD.

BMC Cancer. 2011 Jun 13;11:245. doi: 10.1186/1471-2407-11-245.

6.

Establishing a gingival fibroblast phenotype in a perfused degradable polyurethane scaffold: mediation by TGF-β1, FGF-2, β1-integrin, and focal adhesion kinase.

Cheung JW, McCulloch CA, Santerre JP.

Biomaterials. 2014 Dec;35(38):10025-32. doi: 10.1016/j.biomaterials.2014.09.001.

PMID:
25282621
8.

β1-Integrin cytoskeletal signaling regulates sensory neuron response to matrix dimensionality.

Ribeiro A, Balasubramanian S, Hughes D, Vargo S, Powell EM, Leach JB.

Neuroscience. 2013 Sep 17;248:67-78. doi: 10.1016/j.neuroscience.2013.05.057.

9.
10.

β1-Integrin via NF-κB signaling is essential for acquisition of invasiveness in a model of radiation treated in situ breast cancer.

Nam JM, Ahmed KM, Costes S, Zhang H, Onodera Y, Olshen AB, Hatanaka KC, Kinoshita R, Ishikawa M, Sabe H, Shirato H, Park CC.

Breast Cancer Res. 2013;15(4):R60.

11.

Fibroblast engraftment in the decellularized mouse lung occurs via a β1-integrin-dependent, FAK-dependent pathway that is mediated by ERK and opposed by AKT.

Sun H, Calle E, Chen X, Mathur A, Zhu Y, Mendez J, Zhao L, Niklason L, Peng X, Peng H, Herzog EL.

Am J Physiol Lung Cell Mol Physiol. 2014 Mar 15;306(6):L463-75. doi: 10.1152/ajplung.00100.2013.

12.

The membrane-targeted alkylphosphocholine erufosine interferes with survival signals from the extracellular matrix.

Chometon G, Cappuccini F, Raducanu A, Aumailley M, Jendrossek V.

Anticancer Agents Med Chem. 2014 May;14(4):578-91.

PMID:
24628265
14.

Soluble collagen VI induces tyrosine phosphorylation of paxillin and focal adhesion kinase and activates the MAP kinase erk2 in fibroblasts.

Rühl M, Johannsen M, Atkinson J, Manski D, Sahin E, Somasundaram R, Riecken EO, Schuppan D.

Exp Cell Res. 1999 Aug 1;250(2):548-57.

PMID:
10413607
15.

tPA is a potent mitogen for renal interstitial fibroblasts: role of beta1 integrin/focal adhesion kinase signaling.

Hao S, Shen H, Hou Y, Mars WM, Liu Y.

Am J Pathol. 2010 Sep;177(3):1164-75. doi: 10.2353/ajpath.2010.091269.

16.

A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses.

Härmä V, Virtanen J, Mäkelä R, Happonen A, Mpindi JP, Knuuttila M, Kohonen P, Lötjönen J, Kallioniemi O, Nees M.

PLoS One. 2010 May 3;5(5):e10431. doi: 10.1371/journal.pone.0010431.

17.

FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth.

Tancioni I, Miller NL, Uryu S, Lawson C, Jean C, Chen XL, Kleinschmidt EG, Schlaepfer DD.

Breast Cancer Res. 2015 Mar 28;17:47. doi: 10.1186/s13058-015-0551-x.

18.

The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer.

Chitcholtan K, Sykes PH, Evans JJ.

J Transl Med. 2012 Mar 6;10:38. doi: 10.1186/1479-5876-10-38.

19.

NF-κB regulates radioresistance mediated by β1-integrin in three-dimensional culture of breast cancer cells.

Ahmed KM, Zhang H, Park CC.

Cancer Res. 2013 Jun 15;73(12):3737-48. doi: 10.1158/0008-5472.CAN-12-3537.

20.

Butyrate-treated colonic Caco-2 cells exhibit defective integrin-mediated signaling together with increased apoptosis and differentiation.

Lévy P, Robin H, Bertrand F, Kornprobst M, Capeau J.

J Cell Physiol. 2003 Dec;197(3):336-47.

PMID:
14566963
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