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Year Number of Results
1993 2
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Similar articles for PMID: 18410082

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Page 1
Further structure-activity relationships study of hybrid 7-{[2-(4-phenylpiperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol analogues: identification of a high-affinity D3-preferring agonist with potent in vivo activity with long duration of action.
Biswas S, Zhang S, Fernandez F, Ghosh B, Zhen J, Kuzhikandathil E, Reith ME, Dutta AK. Biswas S, et al. J Med Chem. 2008 Jan 10;51(1):101-17. doi: 10.1021/jm070860r. Epub 2007 Dec 12. J Med Chem. 2008. PMID: 18072730
Development of a Highly Potent D2/D3 Agonist and a Partial Agonist from Structure-Activity Relationship Study of N(6)-(2-(4-(1H-Indol-5-yl)piperazin-1-yl)ethyl)-N(6)-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine Analogues: Implication in the Treatment of Parkinson's Disease.
Das B, Vedachalam S, Luo D, Antonio T, Reith ME, Dutta AK. Das B, et al. J Med Chem. 2015 Dec 10;58(23):9179-95. doi: 10.1021/acs.jmedchem.5b01031. Epub 2015 Nov 30. J Med Chem. 2015. PMID: 26555041 Free PMC article.
Investigation of various N-heterocyclic substituted piperazine versions of 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol: effect on affinity and selectivity for dopamine D3 receptor.
Brown DA, Mishra M, Zhang S, Biswas S, Parrington I, Antonio T, Reith ME, Dutta AK. Brown DA, et al. Bioorg Med Chem. 2009 Jun 1;17(11):3923-33. doi: 10.1016/j.bmc.2009.04.031. Epub 2009 Apr 19. Bioorg Med Chem. 2009. PMID: 19427222 Free PMC article.
Modification of agonist binding moiety in hybrid derivative 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-1-ol/-2-amino versions: impact on functional activity and selectivity for dopamine D2/D3 receptors.
Gopishetty B, Zhang S, Kharkar PS, Antonio T, Reith M, Dutta AK. Gopishetty B, et al. Bioorg Med Chem. 2013 Jun 1;21(11):3164-74. doi: 10.1016/j.bmc.2013.03.059. Epub 2013 Apr 1. Bioorg Med Chem. 2013. PMID: 23623679 Free PMC article.
100 results