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Items: 1 to 20 of 104

1.

Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.

Ober C, Tan Z, Sun Y, Possick JD, Pan L, Nicolae R, Radford S, Parry RR, Heinzmann A, Deichmann KA, Lester LA, Gern JE, Lemanske RF Jr, Nicolae DL, Elias JA, Chupp GL.

N Engl J Med. 2008 Apr 17;358(16):1682-91. doi: 10.1056/NEJMoa0708801.

2.

Genetic variation in chitinase 3-like 1 (CHI3L1) contributes to asthma severity and airway expression of YKL-40.

Gomez JL, Crisafi GM, Holm CT, Meyers DA, Hawkins GA, Bleecker ER, Jarjour N; Severe Asthma Research Program (SARP) Investigators., Cohn L, Chupp GL.

J Allergy Clin Immunol. 2015 Jul;136(1):51-58.e10. doi: 10.1016/j.jaci.2014.11.027.

3.

The chitinase-like protein YKL-40: a possible biomarker of inflammation and airway remodeling in severe pediatric asthma.

Konradsen JR, James A, Nordlund B, Reinius LE, Söderhäll C, Melén E, Wheelock AM, Lödrup Carlsen KC, Lidegran M, Verhoek M, Boot RG, Dahlén B, Dahlén SE, Hedlin G.

J Allergy Clin Immunol. 2013 Aug;132(2):328-35.e5. doi: 10.1016/j.jaci.2013.03.003. Erratum in: J Allergy Clin Immunol. 2013 Nov;132(5):1259. Wheelock, Asa [corrected to Wheelock, Asa M].

PMID:
23628340
4.

Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults.

Rathcke CN, Holmkvist J, Husmoen LL, Hansen T, Pedersen O, Vestergaard H, Linneberg A.

PLoS One. 2009 Jul 1;4(7):e6106. doi: 10.1371/journal.pone.0006106.

5.

A chitinase-like protein in the lung and circulation of patients with severe asthma.

Chupp GL, Lee CG, Jarjour N, Shim YM, Holm CT, He S, Dziura JD, Reed J, Coyle AJ, Kiener P, Cullen M, Grandsaigne M, Dombret MC, Aubier M, Pretolani M, Elias JA.

N Engl J Med. 2007 Nov 15;357(20):2016-27.

6.

Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease.

James AJ, Reinius LE, Verhoek M, Gomes A, Kupczyk M, Hammar U, Ono J, Ohta S, Izuhara K, Bel E, Kere J, Söderhäll C, Dahlén B, Boot RG, Dahlén SE; BIOAIR (Longitudinal Assessment of Clinical Course and Biomarkers in Severe Chronic Airway Disease) Consortium..

Am J Respir Crit Care Med. 2016 Jan 15;193(2):131-42. doi: 10.1164/rccm.201504-0760OC.

PMID:
26372680
7.

A CHI3L1 gene polymorphism is associated with serum levels of YKL-40, a novel sarcoidosis marker.

Kruit A, Grutters JC, Ruven HJ, van Moorsel CC, van den Bosch JM.

Respir Med. 2007 Jul;101(7):1563-71.

8.

CHI3L1 polymorphisms associate with asthma in a Taiwanese population.

Tsai Y, Ko Y, Huang M, Lin M, Wu C, Wang C, Chen Y, Li J, Tseng Y, Wang T.

BMC Med Genet. 2014 Jul 23;15:86. doi: 10.1186/1471-2350-15-86.

9.

Genetic polymorphisms in chitinase 3-like 1 (CHI3L1) are associated with circulating YKL-40 levels, but not with angiographic coronary artery disease in a Chinese population.

Zheng JL, Lu L, Hu J, Zhang RY, Zhang Q, Chen QJ, Shen WF.

Cytokine. 2011 Apr;54(1):51-5. doi: 10.1016/j.cyto.2010.12.018.

PMID:
21257319
10.

Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects.

Nielsen KR, Steffensen R, Boegsted M, Baech J, Lundbye-Christensen S, Hetland ML, Krintel SB, Johnsen HE, Nyegaard M, Johansen JS.

Arthritis Res Ther. 2011 Jun 29;13(3):R109. doi: 10.1186/ar3391.

11.

Asthma and chitinases.

Moffatt MF, Cookson WO.

N Engl J Med. 2008 Apr 17;358(16):1725-6. doi: 10.1056/NEJMe0802072. No abstract available.

PMID:
18403760
12.

CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development.

Usemann J, Frey U, Mack I, Schmidt A, Gorlanova O, Röösli M, Hartl D, Latzin P.

BMC Pulm Med. 2016 May 18;16(1):81. doi: 10.1186/s12890-016-0239-8.

13.

A functional variation in CHI3L1 is associated with severity of liver fibrosis and YKL-40 serum levels in chronic hepatitis C infection.

Berres ML, Papen S, Pauels K, Schmitz P, Zaldivar MM, Hellerbrand C, Mueller T, Berg T, Weiskirchen R, Trautwein C, Wasmuth HE.

J Hepatol. 2009 Feb;50(2):370-6. doi: 10.1016/j.jhep.2008.09.016.

PMID:
19070929
14.

The Association between genetic variations of CHI3L1, levels of the encoded glycoprotein YKL-40 and the lipid profile in a Danish population.

Thomsen SB, Rathcke CN, Skaaby T, Linneberg A, Vestergaard H.

PLoS One. 2012;7(10):e47094. doi: 10.1371/journal.pone.0047094.

15.

Plasma levels of the proinflammatory chitin-binding glycoprotein YKL-40, variation in the chitinase 3-like 1 gene (CHI3L1), and incident cardiovascular events.

Ridker PM, Chasman DI, Rose L, Loscalzo J, Elias JA.

J Am Heart Assoc. 2014 Jun 23;3(3):e000897. doi: 10.1161/JAHA.114.000897.

16.

YKL-40 in asthmatic patients, and its correlations with exacerbation, eosinophils and immunoglobulin E.

Tang H, Fang Z, Sun Y, Li B, Shi Z, Chen J, Zhang T, Xiu Q.

Eur Respir J. 2010 Apr;35(4):757-60. doi: 10.1183/09031936.00034409.

17.

Genetic variation in the promoter region of chitinase 3-like 1 is associated with atopy.

Sohn MH, Lee JH, Kim KW, Kim SW, Lee SH, Kim KE, Kim KH, Lee CG, Elias JA, Lee MG.

Am J Respir Crit Care Med. 2009 Mar 15;179(6):449-56. doi: 10.1164/rccm.200809-1422OC.

PMID:
19106306
18.

YKL-40 is correlated with FEV1 and the asthma control test (ACT) in asthmatic patients: influence of treatment.

Lai T, Chen M, Deng Z, L Y, Wu D, Li D, Wu B.

BMC Pulm Med. 2015 Jan 12;15:1. doi: 10.1186/1471-2466-15-1.

19.

[Association between CHI3L1 SNPs and susceptibility to childhood asthma].

Li JM, Zhang HF, Shen XL, Xie H, Wu XD, Shen T, Wang Y.

Zhongguo Dang Dai Er Ke Za Zhi. 2015 Feb;17(2):144-8. Chinese.

20.

Circulating YKL-40 level, but not CHI3L1 gene variants, is associated with atherosclerosis-related quantitative traits and the risk of peripheral artery disease.

Wu S, Hsu LA, Cheng ST, Teng MS, Yeh CH, Sun YC, Huang HL, Ko YL.

Int J Mol Sci. 2014 Dec 4;15(12):22421-37. doi: 10.3390/ijms151222421.

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