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Items: 1 to 20 of 298

1.

Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice.

Yao H, Edirisinghe I, Yang SR, Rajendrasozhan S, Kode A, Caito S, Adenuga D, Rahman I.

Am J Pathol. 2008 May;172(5):1222-37. doi: 10.2353/ajpath.2008.070765.

2.

NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice.

Kong X, Thimmulappa R, Kombairaju P, Biswal S.

J Immunol. 2010 Jul 1;185(1):569-77. doi: 10.4049/jimmunol.0902315.

3.

NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through reduction-oxidation regulation of NF-κB activity.

Han W, Li H, Cai J, Gleaves LA, Polosukhin VV, Segal BH, Yull FE, Blackwell TS.

J Immunol. 2013 May 1;190(9):4786-94. doi: 10.4049/jimmunol.1201809.

4.

Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues.

Zhang WJ, Wei H, Tien YT, Frei B.

Free Radic Biol Med. 2011 Jun 1;50(11):1517-25. doi: 10.1016/j.freeradbiomed.2011.02.027.

5.

Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling.

Rajendrasozhan S, Chung S, Sundar IK, Yao H, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2010 Feb;298(2):L197-209. doi: 10.1152/ajplung.00265.2009.

6.

p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia.

Sadikot RT, Zeng H, Yull FE, Li B, Cheng DS, Kernodle DS, Jansen ED, Contag CH, Segal BH, Holland SM, Blackwell TS, Christman JW.

J Immunol. 2004 Feb 1;172(3):1801-8.

7.

Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice.

Gao XP, Standiford TJ, Rahman A, Newstead M, Holland SM, Dinauer MC, Liu QH, Malik AB.

J Immunol. 2002 Apr 15;168(8):3974-82.

8.

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

Yang Z, Sharma AK, Marshall M, Kron IL, Laubach VE.

Am J Respir Cell Mol Biol. 2009 Mar;40(3):375-81. doi: 10.1165/rcmb.2008-0300OC.

9.

Bioluminescence imaging of NADPH oxidase activity in different animal models.

Han W, Li H, Segal BH, Blackwell TS.

J Vis Exp. 2012 Oct 22;(68). pii: 3925. doi: 10.3791/3925.

10.

Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo.

Zhang WJ, Wei H, Frei B.

Free Radic Biol Med. 2009 Mar 15;46(6):791-8. doi: 10.1016/j.freeradbiomed.2008.12.003.

11.

Combination effects of cigarette smoke extract and ambient ultrafine particles on endothelial cells.

Mo Y, Wan R, Feng L, Chien S, Tollerud DJ, Zhang Q.

Toxicol In Vitro. 2012 Mar;26(2):295-303. doi: 10.1016/j.tiv.2011.12.001.

12.

Induction of COX-2/PGE(2)/IL-6 is crucial for cigarette smoke extract-induced airway inflammation: Role of TLR4-dependent NADPH oxidase activation.

Lin CC, Lee IT, Yang YL, Lee CW, Kou YR, Yang CM.

Free Radic Biol Med. 2010 Jan 15;48(2):240-54. doi: 10.1016/j.freeradbiomed.2009.10.047.

PMID:
19892012
13.

Advanced oxidation protein products induce inflammatory response in fibroblast-like synoviocytes through NADPH oxidase -dependent activation of NF-κB.

Zheng S, Zhong ZM, Qin S, Chen GX, Wu Q, Zeng JH, Ye WB, Li W, Yuan K, Yao L, Chen JT.

Cell Physiol Biochem. 2013;32(4):972-85. doi: 10.1159/000354500.

14.

Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and fMLP in mice.

Yao H, Yang SR, Edirisinghe I, Rajendrasozhan S, Caito S, Adenuga D, O'Reilly MA, Rahman I.

Am J Respir Cell Mol Biol. 2008 Jul;39(1):7-18. doi: 10.1165/rcmb.2007-0342OC.

15.

Loss of p47phox subunit enhances susceptibility to biomechanical stress and heart failure because of dysregulation of cortactin and actin filaments.

Patel VB, Wang Z, Fan D, Zhabyeyev P, Basu R, Das SK, Wang W, Desaulniers J, Holland SM, Kassiri Z, Oudit GY.

Circ Res. 2013 Jun 7;112(12):1542-56. doi: 10.1161/CIRCRESAHA.111.300299.

16.

Protective role of reactive oxygen species in endotoxin-induced lung inflammation through modulation of IL-10 expression.

Deng J, Wang X, Qian F, Vogel S, Xiao L, Ranjan R, Park H, Karpurapu M, Ye RD, Park GY, Christman JW.

J Immunol. 2012 Jun 1;188(11):5734-40. doi: 10.4049/jimmunol.1101323.

17.
18.

Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and reactive oxygen species production in caveolin-enriched microdomains of the endothelium.

Singleton PA, Pendyala S, Gorshkova IA, Mambetsariev N, Moitra J, Garcia JG, Natarajan V.

J Biol Chem. 2009 Dec 11;284(50):34964-75. doi: 10.1074/jbc.M109.013771.

19.

Cigarette smoke-induced pulmonary inflammation, but not airway remodelling, is attenuated in chemokine receptor 5-deficient mice.

Bracke KR, D'hulst AI, Maes T, Demedts IK, Moerloose KB, Kuziel WA, Joos GF, Brusselle GG.

Clin Exp Allergy. 2007 Oct;37(10):1467-79.

PMID:
17883726
20.

Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia.

Marriott HM, Jackson LE, Wilkinson TS, Simpson AJ, Mitchell TJ, Buttle DJ, Cross SS, Ince PG, Hellewell PG, Whyte MK, Dockrell DH.

Am J Respir Crit Care Med. 2008 Apr 15;177(8):887-95. doi: 10.1164/rccm.200707-990OC.

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