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Items: 1 to 20 of 204

1.

Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions.

Blednov YA, Harris RA.

Int J Neuropsychopharmacol. 2008 Sep;11(6):775-93. doi: 10.1017/S1461145708008584. Epub 2008 Apr 1.

2.

Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intake.

Besheer J, Grondin JJ, Cannady R, Sharko AC, Faccidomo S, Hodge CW.

Biol Psychiatry. 2010 May 1;67(9):812-22. doi: 10.1016/j.biopsych.2009.09.016. Epub 2009 Nov 7.

3.

Acute effects of acamprosate and MPEP on ethanol Drinking-in-the-Dark in male C57BL/6J mice.

Gupta T, Syed YM, Revis AA, Miller SA, Martinez M, Cohn KA, Demeyer MR, Patel KY, Brzezinska WJ, Rhodes JS.

Alcohol Clin Exp Res. 2008 Nov;32(11):1992-8. doi: 10.1111/j.1530-0277.2008.00787.x. Epub 2008 Sep 6.

PMID:
18782337
4.

The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats.

Schroeder JP, Overstreet DH, Hodge CW.

Psychopharmacology (Berl). 2005 Apr;179(1):262-70. Epub 2005 Feb 17.

PMID:
15717208
5.

The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice.

Hodge CW, Miles MF, Sharko AC, Stevenson RA, Hillmann JR, Lepoutre V, Besheer J, Schroeder JP.

Psychopharmacology (Berl). 2006 Jan;183(4):429-38. Epub 2005 Nov 15.

6.

The mGluR5 antagonist MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors.

Chau P, Söderpalm B, Ericson M.

Addict Biol. 2011 Oct;16(4):591-9. doi: 10.1111/j.1369-1600.2011.00343.x. Epub 2011 Jul 25.

PMID:
21790901
7.

The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism.

Olive MF, McGeehan AJ, Kinder JR, McMahon T, Hodge CW, Janak PH, Messing RO.

Mol Pharmacol. 2005 Feb;67(2):349-55. Epub 2004 Nov 17.

8.

Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties.

Lominac KD, Kapasova Z, Hannun RA, Patterson C, Middaugh LD, Szumlinski KK.

Drug Alcohol Depend. 2006 Nov 8;85(2):142-56. Epub 2006 May 11.

PMID:
16697125
9.

The mGluR5 antagonist MPEP suppresses the expression and reinstatement, but not the acquisition, of the ethanol-conditioned place preference in mice.

Lee JY, Choe ES, Yang CH, Choi KH, Cheong JH, Jang CG, Seo JW, Yoon SS.

Pharmacol Biochem Behav. 2016 Jan;140:33-8. doi: 10.1016/j.pbb.2015.10.015. Epub 2015 Oct 30.

PMID:
26521964
10.

Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: blockade by the mGluR5 antagonist MPEP.

Schroeder JP, Spanos M, Stevenson JR, Besheer J, Salling M, Hodge CW.

Neuropharmacology. 2008 Sep;55(4):546-54. doi: 10.1016/j.neuropharm.2008.06.057. Epub 2008 Jul 4.

11.
12.

mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior.

Bäckström P, Bachteler D, Koch S, Hyytiä P, Spanagel R.

Neuropsychopharmacology. 2004 May;29(5):921-8.

13.

mGlu5 receptors are involved in the discriminative stimulus effects of self-administered ethanol in rats.

Besheer J, Stevenson RA, Hodge CW.

Eur J Pharmacol. 2006 Dec 3;551(1-3):71-5. Epub 2006 Sep 8.

14.

The influence of various glutamate receptors antagonists on anxiety-like effect of ethanol withdrawal in a plus-maze test in rats.

Kotlinska J, Bochenski M.

Eur J Pharmacol. 2008 Nov 19;598(1-3):57-63. doi: 10.1016/j.ejphar.2008.09.026. Epub 2008 Sep 27.

PMID:
18838071
15.
16.

The acute anti-craving effect of acamprosate in alcohol-preferring rats is associated with modulation of the mesolimbic dopamine system.

Cowen MS, Adams C, Kraehenbuehl T, Vengeliene V, Lawrence AJ.

Addict Biol. 2005 Sep;10(3):233-42.

PMID:
16109584
17.

Metabotropic glutamate 5 receptors regulate sensitivity to ethanol in mice.

Bird MK, Kirchhoff J, Djouma E, Lawrence AJ.

Int J Neuropsychopharmacol. 2008 Sep;11(6):765-74. doi: 10.1017/S1461145708008572. Epub 2008 Apr 10.

PMID:
18400131
18.

Assessment of GABA-B, metabotropic glutamate, and opioid receptor involvement in an animal model of binge drinking.

Tanchuck MA, Yoneyama N, Ford MM, Fretwell AM, Finn DA.

Alcohol. 2011 Feb;45(1):33-44. doi: 10.1016/j.alcohol.2010.07.009. Epub 2010 Sep 16.

19.

Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats.

Adams CL, Cowen MS, Short JL, Lawrence AJ.

Int J Neuropsychopharmacol. 2008 Mar;11(2):229-41. Epub 2007 May 22.

PMID:
17517168
20.

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